Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Eudoxia Hatzivassiliou"'
Autor:
Paul Hadweh, Iro Chaitoglou, Maria Joao Gravato-Nobre, Petros Ligoxygakis, George Mosialos, Eudoxia Hatzivassiliou
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0191864 (2018)
The human cylindromatosis tumor suppressor (HsCyld) has attracted extensive attention due to its association with the development of multiple types of cancer. HsCyld encodes a deubiquitinating enzyme (HsCYLD) with a broad range of functions that incl
Externí odkaz:
https://doaj.org/article/4ff9bfc03ef343d5b8b468904f798cf6
Autor:
Christos Gonidas, Eudoxia Hatzivassiliou, Alexander Hardas, Theofilos Poutahidis, Chrysanthi Ainali, Xaralabos Varelas, Joseph G. Kern, Athanasios Pseftogas, Dimitra Dafou, Anastasia Tsingotjidou, Konstantinos Xanthopoulos, Emmanuel Panteris, George Mosialos
Publikováno v:
Cancers
Cancers, Vol 12, Iss 2047, p 2047 (2020)
Volume 12
Issue 8
Cancers, Vol 12, Iss 2047, p 2047 (2020)
Volume 12
Issue 8
Downregulation of the cylindromatosis (CYLD) tumor suppressor has been associated with breast cancer development and progression. Here, we report a critical role for CYLD in maintaining the phenotype of mammary epithelial cells in vitro and in vivo.
Autor:
Dimitrios Koutsoumparis, Konstantinos Hatzimouratidis, Soultana Meditskou, Eudoxia Hatzivassiliou, Periklis Koukourikis, Dimitrios Papanikolaou, Kyriakos Moysidis, Pinelopi Ioannidou
Publikováno v:
Urologic oncology. 38(4)
Background: Chromophobe renal cell carcinoma (chRCC) subtype accounts for almost 5% of total RCC cases. It carries the best prognosis among the rest of RCC types. However, patients with metastatic chRCC disease have worse prognosis than patients with
Autor:
George Mosialos, Konstantinos Xanthopoulos, Theofilos Poutahidis, Eudoxia Hatzivassiliou, Konstantinos Teliousis, Demetrios N Karatzas, Dimitris L. Kontoyiannis, Panorea Kotantaki, Athanasios Pseftogas
Publikováno v:
Cellular Oncology. 39:287-293
CYLD is a tumor suppressor that has been linked to the development of various human malignancies, including colon cancer. The tumor-suppressing function of CYLD is associated with its deubiquitinating activity, which maps to the carboxyl-terminal reg
Publikováno v:
Cellular Signalling. 26:2730-2737
TRAFs constitute a family of proteins that have been implicated in signal transduction by immunomodulatory cellular receptors and viral proteins. TRAF2 and TRAF6 have an E3-ubiquitin ligase activity, which is dependent on the integrity of their RING
Autor:
Paul Hadweh, Claire Psyllaki, George Mosialos, Eudoxia Hatzivassiliou, Konstantinos Xanthopoulos, Dimitra Dafou, Athanasios Pseftogas, Timoklia Orfanidou
Publikováno v:
Anticancer research. 37(7)
Background/aim The cylindromatosis tumor suppressor (CYLD) has been implicated in the inhibition of human breast cancer development by virtue of the poor prognosis of patients with down-regulated CYLD expression. In order to investigate the mechanism
Autor:
Charilaos Megas, Dario A. A. Vignali, George Mosialos, Eudoxia Hatzivassiliou, Qian Yin, Elli Marinopoulou, Paul Hadweh
Publikováno v:
Cellular Signalling. 23:772-777
TRAF6 is an E3 ubiquitin ligase that plays a pivotal role in the activation of NF-κB by innate and adaptive immunity stimuli. TRAF6 consists of a highly conserved carboxyl terminal TRAF-C domain which is preceded by a coiled coil domain and an amino
Autor:
George Mosialos, Petros Ligoxygakis, Iro Chaitoglou, Eudoxia Hatzivassiliou, Paul Hadweh, Maria J. Gravato-Nobre
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0191864 (2018)
PLoS ONE
PLoS ONE
The human cylindromatosis tumor suppressor (HsCyld) has attracted extensive attention due to its association with the development of multiple types of cancer. HsCyld encodes a deubiquitinating enzyme (HsCYLD) with a broad range of functions that incl
Autor:
Elliott Kieff, Christos Tzimas, Minas Arsenakis, Gianna Michailidou, Eudoxia Hatzivassiliou, George Mosialos
Publikováno v:
Cellular Signalling. 18:83-92
TRAF2 mediates activation of the transcription factors NF-kappaB and AP1 by TNF. A yeast two-hybrid screen of a human cDNA library identified a ubiquitin specific protease homologue (USP31) as a TRAF2-interacting protein. Two cDNAs encoding for USP31
Publikováno v:
Journal of Virology. 79:5215-5219
The Epstein-Barr virus latent membrane protein 1 (LMP1) is an oncoprotein which mimics activated tumor necrosis factor receptor family members. Here we demonstrate the principle that an inducible association of the LMP1 cytoplasmic carboxyl terminus