Zobrazeno 1 - 10
of 282
pro vyhledávání: '"Eudenilson L, Albuquerque"'
Autor:
Valeska S. de Sena Pereira, Flávio da Silva Emery, Lis Lobo, Fátima Nogueira, Jonas I. N. Oliveira, Umberto L. Fulco, Eudenilson L. Albuquerque, Alejandro M. Katzin, Valter F. de Andrade-Neto
Publikováno v:
Malaria Journal, Vol 17, Iss 1, Pp 1-11 (2018)
Abstract Background Plasmodium falciparum has shown multidrug resistance, leading to the necessity for the development of new drugs with novel targets, such as the synthesis of isoprenic precursors, which are excellent targets because the pathway is
Externí odkaz:
https://doaj.org/article/af877e10390245d8b11e827d55bcac82
Publikováno v:
Journal of Raman Spectroscopy. 53:715-723
Autor:
Eveline M. Bezerra, Érika C. de Alvarenga, Ricardo P. dos Santos, Jeanlex S. de Sousa, Umberto L. Fulco, Valder N. Freire, Eudenilson L. Albuquerque, Roner F. da Costa
Publikováno v:
RSC Advances. 12:28395-28404
Losartan (LST) is a potent and selective angiotensin II (Ang II) type 1 (AT1) receptor antagonist widely used in the treatment of hypertension. The formation of Ang II is catalyzed by the angiotensin I-converting enzyme (ACE) through proteolytic clea
Autor:
Eveline M. Bezerra, João R. Bezerra-Neto, Francisco A. M. Sales, Ricardo P. dos Santos, Alice M. C. Martins, Pedro de Lima-Neto, Ewerton W. S. Caetano, Eudenilson L. Albuquerque, Valder N. Freire
Publikováno v:
Molecules, Vol 19, Iss 4, Pp 4145-4156 (2014)
UV-vis optical absorption spectra of the antitrypanocidal drug benznidazole solvated in water were measured for various concentrations. The spectra show a prominent peak around 3.80 eV, while deconvolution of the UV-vis optical absorption spectra rev
Externí odkaz:
https://doaj.org/article/d39e8c6def5f4b9fbdc41ca4ade3be55
Publikováno v:
Physical Chemistry Chemical Physics. 23:21207-21217
We investigate the interaction between the programmed cell death protein 1 (PD-1) and the programmed cell death ligand 1 (PD-L1), as well as the immuno-oncological drugs pembrolizumab (PEM), and nivolumab (NIV), through quantum chemistry methods base
Autor:
Daniel Melo de Oliveira Campos, J. I. N. Oliveira, Eudenilson L. Albuquerque, Katyanna S Bezerra, Umberto L. Fulco, Stephany C Esmaile
Publikováno v:
Physical Chemistry Chemical Physics. 22:15683-15695
The emergent Zika virus (ZIKV) infection has become a threat to global health due to its association with severe neurological abnormalities, namely Guillain-Barré Syndrome (GBS) in adults and Congenital Zika virus Syndrome (CZS) in neonates. Many st
Autor:
Eudenilson L. Albuquerque, J. F. Vianna, Katyanna S Bezerra, Umberto L. Fulco, J. X. Lima Neto, J. Ivan Nobre Oliveira
Publikováno v:
New Journal of Chemistry. 44:5903-5912
Prostate cancer is the most prevalent malignancy in men, and one of the top causes of cancer death. Great advances have been presented regarding the treatment and understanding of the biology of this disease although, unfortunately, the available the
Autor:
Eudenilson L. Albuquerque, Vinícius Manzoni, José X. Lima Neto, E. D. Barbosa, Umberto L. Fulco, J. I. N. Oliveira, Katyanna S Bezerra, Vanessa de Paula Soares-Rachetti
Publikováno v:
Journal of Chemical Information and Modeling. 60:1005-1018
GABAB is a G protein-coupled receptor that functions as a constitutive heterodimer composed of the GABAB1a/b and GABAB2 subunits. It mediates slow and prolonged inhibitory neurotransmission in the nervous system, representing an attractive target for
Autor:
José X. Lima Neto, Leonardo D. Machado, Stephany C Esmaile, Eudenilson L. Albuquerque, Katyanna S Bezerra, Umberto L. Fulco, J. I. N. Oliveira, Valder N. Freire
Publikováno v:
The Journal of Physical Chemistry B. 123:6421-6429
We intend to investigate the drug-binding energy of each nucleotide inside the aminoglycoside hygromycin B (hygB) binding site of 30S ribosomal RNA (rRNA) subunit by using the molecular fractionation with conjugate caps (MFCC) strategy based on the d
Autor:
Eudenilson L. Albuquerque, J. I. N. Oliveira, J. F. Vianna, Umberto L. Fulco, Katyanna S Bezerra
Publikováno v:
Physical Chemistry Chemical Physics. 21:19192-19200
Despite advances, tuberculosis remains a significant infectious disease, whose mortality presents alarming numbers. Although it can be cured, the number of cases of antimicrobial resistant strains is increasing, requiring the use of less efficient se