Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Euan B. McLean"'
Publikováno v:
Organic Letters. 24:686-691
A mild and inexpensive method for direct hydrodecarboxylation of aliphatic carboxylic acids has been developed. The reaction does not require metals, light, or catalysts, rendering the protocol operationally simple, easy to scale, and more sustainabl
Autor:
Holly McErlain, Euan B. McLean, Timaeus E. F. Morgan, Valeria K. Burianova, Adriana A. S. Tavares, Andrew Sutherland
Publikováno v:
McErlain, H, Mclean, E B, Morgan, T E F, Burianova, V K, Tavares, A A S & Sutherland, A 2022, ' Organocatalytic Asymmetric Synthesis of SynVesT-1, a Synaptic Density Positron Emission Tomography Imaging Agent ', The Journal of Organic Chemistry (JOC), vol. 87, no. 21, pp. 14443-14451 . https://doi.org/10.1021/acs.joc.2c01895
Heterocyclic nonacetamide ligands are used as positron emission tomography (PET) imaging agents of the synaptic vesicle glycoprotein 2A (SV2A), with potential applications in the diagnosis of various neuropsychiatric diseases. To date, the main synth
Publikováno v:
Organic Letters
Estopina-Duran, S, Mclean, E, Donnelly, L, Hockin, B & Taylor, J 2020, ' Arylboronic Acid Catalyzed C-Alkylation and Allylation Reactions Using Benzylic Alcohols ', Organic Letters, vol. 22, no. 19, pp. 7547-7551 . https://doi.org/10.1021/acs.orglett.0c02736
Estopina-Duran, S, Mclean, E, Donnelly, L, Hockin, B & Taylor, J 2020, ' Arylboronic Acid Catalyzed C-Alkylation and Allylation Reactions Using Benzylic Alcohols ', Organic Letters, vol. 22, no. 19, pp. 7547-7551 . https://doi.org/10.1021/acs.orglett.0c02736
The arylboronic acid catalyzed dehydrative C-alkylation of 1,3-diketones and 1,3-ketoesters using secondary benzylic alcohols as the electrophile is reported, forming new C–C bonds (19 examples, up to 98% yield) with the release of water as the onl
Publikováno v:
Organic Letters. 22:6977-6981
Gold-catalyzed hydroarylation of unactivated alkynes with indoles have previously been reported to proceed with double indole addition to produce symmetrical bis(indolyl)methanes (BIMs). We demonstrate for the first time that the selectivity of the g
Autor:
Bryony M. Hockin, Liam J. Donnelly, Euan B. Mclean, Susana Estopiñá-Durán, Alexandra M. Z. Slawin, James E. Taylor
Publikováno v:
Estopina-Duran, S, Donnelly, L, Mclean, E, Hockin, B, Slawin, A M Z & Taylor, J 2019, ' Aryl Boronic Acid Catalysed Dehydrative Substitution of Benzylic Alcohols for C−O Bond Formation ', Chemistry-A European Journal, vol. 25, no. 15, pp. 3950-3956 . https://doi.org/10.1002/chem.201806057
We thank the University of St Andrews and the EPSRC for the award of a DTA studentship (S.E.-D.). We would also like to thank the EPSRC, University of St Andrews, and CRITICAT Centre for Doctoral Training for financial support [Ph.D. studentships to
Publikováno v:
Chemical Communications. 55:4238-4241
The use of copper catalysis with visible light photoredox catalysis in a cooperative fashion has recently emerged as a versatile means of developing new C–C bond forming reactions. In this work, dual copper and photoredox catalysis is exploited to
Autor:
Ai-Lan Lee, Euan B. McLean
Publikováno v:
Tetrahedron. 74:4881-4902
The merger of transition metal catalysis with visible light photoredox catalysis in a cooperative fashion has recently emerged as a versatile way of developing new synthetic methodologies. This review will focus on the relatively new but fast expandi
Publikováno v:
Chemical communications (Cambridge, England). 55(29)
The use of copper catalysis with visible light photoredox catalysis in a cooperative fashion has recently emerged as a versatile means of developing new C-C bond forming reactions. In this work, dual copper and photoredox catalysis is exploited to ef
Autor:
Euan B. McLean, Ai-Lan Lee
Publikováno v:
Nature Chemistry. 11:760-761