Zobrazeno 1 - 10
of 525
pro vyhledávání: '"Euan A, Ashley"'
Autor:
Alexey Kolesnikov, Daniel Cook, Maria Nattestad, Lucas Brambrink, Brandy McNulty, John Gorzynski, Sneha Goenka, Euan A. Ashley, Miten Jain, Karen H. Miga, Benedict Paten, Pi-Chuan Chang, Andrew Carroll, Kishwar Shafin
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Long-read sequencing technology has enabled variant detection in difficult-to-map regions of the genome and enabled rapid genetic diagnosis in clinical settings. Rapidly evolving third-generation sequencing platforms like Pacific Biosciences
Externí odkaz:
https://doaj.org/article/9736ff93823742a28239875aa6195f95
Autor:
Varsha Gupta, Sokratis Kariotis, Mohammed D. Rajab, Niamh Errington, Elham Alhathli, Emmanuel Jammeh, Martin Brook, Naomi Meardon, Paul Collini, Joby Cole, Jim M. Wild, Steven Hershman, Ali Javed, A. A. Roger Thompson, Thushan de Silva, Euan A. Ashley, Dennis Wang, Allan Lawrie
Publikováno v:
npj Digital Medicine, Vol 6, Iss 1, Pp 1-11 (2023)
Abstract Previous studies have associated COVID-19 symptoms severity with levels of physical activity. We therefore investigated longitudinal trajectories of COVID-19 symptoms in a cohort of healthcare workers (HCWs) with non-hospitalised COVID-19 an
Externí odkaz:
https://doaj.org/article/b4cfdc189a5a47bda93eae8d4dfd53a6
Autor:
Mahyar Salek, Nianzhen Li, Hou-Pu Chou, Kiran Saini, Andreja Jovic, Kevin B. Jacobs, Chassidy Johnson, Vivian Lu, Esther J. Lee, Christina Chang, Phuc Nguyen, Jeanette Mei, Krishna P. Pant, Amy Y. Wong-Thai, Quillan F. Smith, Stephanie Huang, Ryan Chow, Janifer Cruz, Jeff Walker, Bryan Chan, Thomas J. Musci, Euan A. Ashley, Maddison (Mahdokht) Masaeli
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-11 (2023)
Abstract Cells are the singular building blocks of life, and a comprehensive understanding of morphology, among other properties, is crucial to the assessment of underlying heterogeneity. We developed Computational Sorting and Mapping of Single Cells
Externí odkaz:
https://doaj.org/article/f1450d1cfe9f4bbc9e8dd7248e506562
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
IntroductionLeft ventricular hypertrophy (LVH) detection techniques on by electrocardiogram (ECG) are cumbersome to remember with modest performance. This study validated a rapid technique for LVH detection and measured its performance against other
Externí odkaz:
https://doaj.org/article/c245429b7f8d45f4b65682aa41a09b40
Autor:
Gareth J Williams, BMBS, Abdulaziz Al-Baraikan, MSc, Frank E Rademakers, ProfMD, Fabio Ciravegna, ProfPhD, Frans N van de Vosse, ProfPhD, Allan Lawrie, ProfPhD, Alexander Rothman, PhD, Euan A Ashley, ProfDphil, Martin R Wilkins, ProfMD, Patricia V Lawford, ProfPhD, Stig W Omholt, ProfPhD, Ulrik Wisløff, ProfPhD, D Rodney Hose, ProfPhD, Timothy J A Chico, ProfMD, Julian P Gunn, ProfMD, Paul D Morris, PhD
Publikováno v:
The Lancet: Digital Health, Vol 5, Iss 7, Pp e467-e476 (2023)
Summary: The past decade has seen a dramatic rise in consumer technologies able to monitor a variety of cardiovascular parameters. Such devices initially recorded markers of exercise, but now include physiological and health-care focused measurements
Externí odkaz:
https://doaj.org/article/2dae23871e944ee9a8e3aa1c127e5a9a
Autor:
Arthur A. M. Wilde, Christopher Semsarian, Manlio F. Márquez, Alireza Sepehri Shamloo, Michael J. Ackerman, Euan A. Ashley, Back Sternick Eduardo, Héctor Barajas‐Martinez, Elijah R. Behr, Connie R. Bezzina, Jeroen Breckpot, Philippe Charron, Priya Chockalingam, Lia Crotti, Michael H. Gollob, Steven Lubitz, Naomasa Makita, Seiko Ohno, Martín Ortiz‐Genga, Luciana Sacilotto, Eric Schulze‐Bahr, Wataru Shimizu, Nona Sotoodehnia, Rafik Tadros, James S. Ware, David S. Winlaw, Elizabeth S. Kaufman, Takeshi Aiba, Andreas Bollmann, Jong‐Il Choi, Aarti Dalal, Francisco Darrieux, John Giudicessi, Mariana Guerchicoff, Kui Hong, Andrew D. Krahn, Ciorsti Mac Intyre, Judith A. Mackall, Lluís Mont, Carlo Napolitano, Pablo Ochoa Juan, Petr Peichl, Alexandre C. Pereira, Peter J. Schwartz, Jon Skinner, Christoph Stellbrink, Jacob Tfelt‐Hansen, Thomas Deneke
Publikováno v:
Journal of Arrhythmia, Vol 38, Iss 4, Pp 491-553 (2022)
Externí odkaz:
https://doaj.org/article/065b869d10df4d35a27b0f57e20fcc2b
Autor:
Victoria N. Parikh, Alexander G. Ioannidis, David Jimenez-Morales, John E. Gorzynski, Hannah N. De Jong, Xiran Liu, Jonasel Roque, Victoria P. Cepeda-Espinoza, Kazutoyo Osoegawa, Chris Hughes, Shirley C. Sutton, Nathan Youlton, Ruchi Joshi, David Amar, Yosuke Tanigawa, Douglas Russo, Justin Wong, Jessie T. Lauzon, Jacob Edelson, Daniel Mas Montserrat, Yongchan Kwon, Simone Rubinacci, Olivier Delaneau, Lorenzo Cappello, Jaehee Kim, Massa J. Shoura, Archana N. Raja, Nathaniel Watson, Nathan Hammond, Elizabeth Spiteri, Kalyan C. Mallempati, Gonzalo Montero-Martín, Jeffrey Christle, Jennifer Kim, Anna Kirillova, Kinya Seo, Yong Huang, Chunli Zhao, Sonia Moreno-Grau, Steven G. Hershman, Karen P. Dalton, Jimmy Zhen, Jack Kamm, Karan D. Bhatt, Alina Isakova, Maurizio Morri, Thanmayi Ranganath, Catherine A. Blish, Angela J. Rogers, Kari Nadeau, Samuel Yang, Andra Blomkalns, Ruth O’Hara, Norma F. Neff, Christopher DeBoever, Sándor Szalma, Matthew T. Wheeler, Christian M. Gates, Kyle Farh, Gary P. Schroth, Phil Febbo, Francis deSouza, Omar E. Cornejo, Marcelo Fernandez-Vina, Amy Kistler, Julia A. Palacios, Benjamin A. Pinsky, Carlos D. Bustamante, Manuel A. Rivas, Euan A. Ashley
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
There is a genetic component to the risk of severe COVID-19, but the genetic effects are difficult to separate from social constructs that covary with genetic ancestry. To address this, the authors identify determinants of COVID-19 severity using adm
Externí odkaz:
https://doaj.org/article/10002eca5587461185e42393a7dc16a5
Autor:
Juan R. Gimeno, Iacopo Olivotto, Ana Isabel Rodríguez, Carolyn Y. Ho, Adrián Fernández, Alejandro Quiroga, Mari Angeles Espinosa, Cristina Gómez‐González, María Robledo, Lucas Tojal‐Sierra, Sharlene M. Day, Anjali Owens, Roberto Barriales‐Villa, Jose María Larrañaga, Jose Rodríguez‐Palomares, Maribel González‐del‐Hoyo, Jesús Piqueras‐Flores, Nosheen Reza, Olga Chumakova, Euan A. Ashley, Victoria Parikh, Matthew Wheeler, Daniel Jacoby, Alexandre C. Pereira, Sara Saberi, Adam S. Helms, Eduardo Villacorta, María Gallego‐Delgado, Daniel deCastro, Fernando Domínguez, Tomás Ripoll‐Vera, Esther Zorio‐Grima, José Carlos Sánchez‐Martínez, Ana García‐Álvarez, Elena Arbelo, María Victoria Mogollón, María Eugenia Fuentes‐Cañamero, Elias Grande, Carlos Peña, Lorenzo Monserrat, Neal K. Lakdawala, Dilema International Cardiomyopathy and Heart Failure Registry and international SHaRe (Sarcomeric Human Cardiomyopathy Registry) Investigators group
Publikováno v:
ESC Heart Failure, Vol 9, Iss 4, Pp 2189-2198 (2022)
Abstract Aims To describe the natural history of SARS‐CoV‐2 infection in patients with hypertrophic cardiomyopathy (HCM) compared with a control group and to identify predictors of adverse events. Methods and results Three hundred and five patien
Externí odkaz:
https://doaj.org/article/91483f6a810740f68b374d86c8670633
Autor:
Theresia M. Schnurr, Sophia Figueroa Katz, Johanne M. Justesen, Jack W. O’Sullivan, Peter Saliba‐Gustafsson, Themistocles L. Assimes, Ivan Carcamo‐Orive, Aijaz Ahmed, Euan A. Ashley, Torben Hansen, Joshua W. Knowles
Publikováno v:
Hepatology Communications, Vol 6, Iss 7, Pp 1516-1526 (2022)
Abstract Genetic predisposition and unhealthy lifestyle are risk factors for nonalcoholic fatty liver disease (NAFLD). We investigated whether the genetic risk of NAFLD is modified by physical activity, muscular fitness, and/or adiposity. In up to 24
Externí odkaz:
https://doaj.org/article/b7e68fe269a94a0b8a3d202f933a8ff4
Autor:
Peter-James H. Zushin, Yang Zhou, Audrey Li, Euan A. Ashley, Matthew T. Wheeler, Joseph C. Wu
Publikováno v:
Stem Cell Research, Vol 67, Iss , Pp 103019- (2023)
Dilated cardiomyopathies (DCM) are one of the main causes of heart failure as one ages. BAG3 is a chaperone protein that is heavily implicated in the development of DCM and speed of progression toward heart failure. Here we generate two human iPSC li
Externí odkaz:
https://doaj.org/article/044ef1133bed4c6581cd1e47088d94cc