Zobrazeno 1 - 10
of 446
pro vyhledávání: '"Etty N Benveniste"'
Autor:
Huixian Hong, Yong Wang, Marissa Menard, Jessica A. Buckley, Lianna Zhou, Laura Volpicelli-Daley, David G. Standaert, Hongwei Qin, Etty N. Benveniste
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-18 (2024)
Abstract Parkinson’s disease (PD) is characterized by neuroinflammation, progressive loss of dopaminergic neurons, and accumulation of α-synuclein (α-Syn) into insoluble aggregates called Lewy pathology. The Line 61 α-Syn mouse is an established
Externí odkaz:
https://doaj.org/article/2b84aadb4e09490db4dee86d56fe683b
Autor:
Cayla Hurst, Toni R. Leeth, Etty N. Benveniste, Robert P. Kimberly, Craig Hoesley, LaKisha Mack, Mona N. Fouad, David A. Rogers, Selwyn M. Vickers, Anupam Agarwal
Publikováno v:
Medical Education Online, Vol 28, Iss 1 (2023)
ABSTRACTThe University of Alabama at Birmingham Heersink School of Medicine established the Pittman Scholars Program in 2015 to elevate scientific impact and to support the recruitment and retention of highly competitive junior faculty. The authors e
Externí odkaz:
https://doaj.org/article/29d62391615e4f65b8221145b324db6c
Autor:
Lianna Zhou, Zhaoqi Yan, Wei Yang, Jessica A. Buckley, Sameer Al Diffalha, Etty N. Benveniste, Hongwei Qin
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionMyeloid cells play a critical role in the pathogenesis of Inflammatory Bowel Diseases (IBDs), including Ulcerative Colitis (UC) and Crohn’s Disease (CD). Dysregulation of the JAK/STAT pathway is associated with many pathological conditi
Externí odkaz:
https://doaj.org/article/f7eb958c95dd444e9093312ed1377233
Autor:
Enquan Xu, Ravindra Boddu, Hisham A. Abdelmotilib, Arpine Sokratian, Kaela Kelly, Zhiyong Liu, Nicole Bryant, Sidhanth Chandra, Samantha M. Carlisle, Elliot J. Lefkowitz, Ashley S. Harms, Etty N. Benveniste, Talene A. Yacoubian, Laura A. Volpicelli-Daley, David G. Standaert, Andrew B. West
Publikováno v:
Molecular Neurodegeneration, Vol 17, Iss 1, Pp 1-19 (2022)
Abstract Background Leucine rich repeat kinase 2 (LRRK2) and SNCA are genetically linked to late-onset Parkinson’s disease (PD). Aggregated α-synuclein pathologically defines PD. Recent studies identified elevated LRRK2 expression in pro-inflammat
Externí odkaz:
https://doaj.org/article/650263aba80f4a2ebcfa23775edbadc2
Autor:
Samantha M. Carlisle, Hongwei Qin, R. Curtis Hendrickson, Jordana E. Muwanguzi, Elliot J. Lefkowitz, Richard E. Kennedy, Zhaoqi Yan, Talene A. Yacoubian, Etty N. Benveniste, Andrew B. West, Ashley S. Harms, David G. Standaert
Publikováno v:
npj Parkinson's Disease, Vol 7, Iss 1, Pp 1-10 (2021)
Abstract Increasing evidence supports the role of brain and systemic inflammation in the etiology of Parkinson disease (PD). We used gene expression profiling to examine the activation state of peripheral blood monocytes in 18 patients with early, un
Externí odkaz:
https://doaj.org/article/05be2d31917548968fb8f99ff6f9f339
Autor:
Hyunmin Koo, Braden C. McFarland, Joseph A. Hakim, David K. Crossman, Michael R. Crowley, J. Martin Rodriguez, Etty N. Benveniste, Casey D. Morrow
Publikováno v:
Royal Society Open Science, Vol 7, Iss 4 (2020)
To understand the origins of the infant gut microbial community, we have used a published metagenomic dataset of the faecal microbiome of mothers and their related infants at early (4, 7 and 21 days) and late times (6–15 months) following birth. Us
Externí odkaz:
https://doaj.org/article/fb429ab9a2c949469dbee4efa266058a
Autor:
Huixian Hong, Etty N. Benveniste
Publikováno v:
Biomedicines, Vol 9, Iss 12, p 1932 (2021)
Protein Kinase CK2, a constitutively active serine/threonine kinase, fulfills its functions via phosphorylating hundreds of proteins in nearly all cells. It regulates a variety of cellular signaling pathways and contributes to cell survival, prolifer
Externí odkaz:
https://doaj.org/article/c0aefc9bbc4545249790e89d753d7fec
Autor:
Wei Yang, Hairong Wei, Gloria A. Benavides, William J. Turbitt, Jessica A. Buckley, Xiaosen Ouyang, Lianna Zhou, Jianhua Zhang, Laurie E. Harrington, Victor M. Darley-Usmar, Hongwei Qin, Etty N. Benveniste
Publikováno v:
The Journal of Immunology. 209:896-906
Protein kinase CK2 is a serine/threonine kinase composed of two catalytic subunits (CK2α and/or CK2α′) and two regulatory subunits (CK2β). CK2 promotes cancer progression by activating the NF-κB, PI3K/AKT/mTOR, and JAK/STAT pathways, and also i
PDF file - 102K, JSI-124 induces the mRNA expression of inflammatory genes in human xenograft GBM cells and murine primary astrocytes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7928d2c26be7455c0960c5b851d4d10
https://doi.org/10.1158/1541-7786.22510350
https://doi.org/10.1158/1541-7786.22510350
Autor:
Etty N. Benveniste, Dennis Huszar, Susan E. Nozell, Ying Zheng, Hao Yu, G. Yancey Gillespie, Catherine P. Langford, Jing-Yuan Ma, Braden C. McFarland
PDF file - 72K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b1493cd85c16b7f06e8a8389b91d7a9
https://doi.org/10.1158/1535-7163.22496371
https://doi.org/10.1158/1535-7163.22496371