Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Ettore, Napolitano"'
Autor:
Dr. Chiara Platella, Dr. Ettore Napolitano, Dr. Claudia Riccardi, Prof. Domenica Musumeci, Prof. Daniela Montesarchio
Publikováno v:
ChemistryOpen, Vol 11, Iss 5, Pp n/a-n/a (2022)
Abstract DNA G‐quadruplexes (G4s) are key structures for the development of targeted anticancer therapies. In this context, ligands selectively interacting with G4s can represent valuable anticancer drugs. Aiming at speeding up the identification o
Externí odkaz:
https://doaj.org/article/3d80de0de2424d259f23abe46e82e96b
Autor:
Andrea Criscuolo, Ettore Napolitano, Claudia Riccardi, Domenica Musumeci, Chiara Platella, Daniela Montesarchio
Publikováno v:
Pharmaceutics, Vol 14, Iss 11, p 2361 (2022)
G-quadruplexes turned out to be important targets for the development of novel targeted anticancer/antiviral therapies. More than 3000 G-quadruplex small-molecule ligands have been described, with most of them exerting anticancer/antiviral activity b
Externí odkaz:
https://doaj.org/article/5523c6c8e44649f48aa9e1583f96a56f
Autor:
Chiara Platella, Rosa Gaglione, Ettore Napolitano, Angela Arciello, Valentina Pirota, Filippo Doria, Domenica Musumeci, Daniela Montesarchio
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 19, p 10624 (2021)
G-quadruplex existence was proved in cells by using both antibodies and small molecule fluorescent probes. However, the G-quadruplex probes designed thus far are structure- but not conformation-specific. Recently, a core-extended naphthalene diimide
Externí odkaz:
https://doaj.org/article/b0bf04c5bc1c450c9582e5c8aa286a2c
Autor:
Pasqualina Liana Scognamiglio, Chiara Platella, Ettore Napolitano, Domenica Musumeci, Giovanni Nicola Roviello
Publikováno v:
Molecules, Vol 26, Iss 12, p 3558 (2021)
Peptides and their synthetic analogs are a class of molecules with enormous relevance as therapeutics for their ability to interact with biomacromolecules like nucleic acids and proteins, potentially interfering with biological pathways often involve
Externí odkaz:
https://doaj.org/article/777b280f684b48549278643b0687b35b
Autor:
Ettore Napolitano, Claudia Riccardi, Rosa Gaglione, Angela Arciello, Valentina Pirota, Alice Triveri, Filippo Doria, Domenica Musumeci, Daniela Montesarchio
To develop efficient anticancer theranostic systems, we studied the interaction between a cyanine dye, analogue of thiazole orange (named CyOH), and two G-quadruplex-forming aptamers, V7t1 and 3R02, recognizing the Vascular Endothelial Growth Factor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::833b4f7f04ea00607a06b5b63129e9c1
https://hdl.handle.net/11588/901935
https://hdl.handle.net/11588/901935
Publikováno v:
Molecules, Vol 25, Iss 22, p 5227 (2020)
Multivalent interactions frequently occur in biological systems and typically provide higher binding affinity and selectivity in target recognition than when only monovalent interactions are operative. Thus, taking inspiration by nature, bivalent or
Externí odkaz:
https://doaj.org/article/6f0361881f0d4a9289f4fda49cf1434b
Autor:
Ettore, Napolitano, Claudia, Riccardi, Rosa, Gaglione, Angela, Arciello, Valentina, Pirota, Alice, Triveri, Filippo, Doria, Domenica, Musumeci, Daniela, Montesarchio
Publikováno v:
International journal of biological macromolecules.
To develop efficient anticancer theranostic systems, we studied the interaction between a cyanine dye, analogue of thiazole orange (named CyOH), and two G-quadruplex-forming aptamers, V7t1 and 3R02, recognizing the Vascular Endothelial Growth Factor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9c4f06f58b2ebb573328a3817b218d80
https://pubmed.ncbi.nlm.nih.gov/36270405
https://pubmed.ncbi.nlm.nih.gov/36270405
Autor:
Chiara Platella, Ettore Napolitano, Claudia Riccardi, Domenica Musumeci, Daniela Montesarchio
DNA G-quadruplexes (G4s) are key structures for the development of targeted anticancer therapies. In this context, ligands selectively interacting with G4s can represent valuable anticancer drugs. Aiming at speeding up the identification of G4-target
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61e82eb6468484710518b7bb76c01eb1
http://hdl.handle.net/11588/885641
http://hdl.handle.net/11588/885641
Autor:
Rosa Gaglione, Ettore Napolitano, Chiara Platella, Valentina Pirota, Daniela Montesarchio, Filippo Doria, Angela Arciello, Domenica Musumeci
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 10624, p 10624 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 19
International Journal of Molecular Sciences
Volume 22
Issue 19
G-quadruplex existence was proved in cells by using both antibodies and small molecule fluorescent probes. However, the G-quadruplex probes designed thus far are structure- but not conformation-specific. Recently, a core-extended naphthalene diimide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa1601cdac926c38b7b5fb9ff168bcaa
https://www.mdpi.com/1422-0067/22/19/10624
https://www.mdpi.com/1422-0067/22/19/10624
Autor:
Claudia Riccardi, Domenica Musumeci, Ettore Napolitano, Mariarosa A. B. Melone, Chiara Platella, Daniela Montesarchio
The vascular endothelial growth factor (VEGF) family and its receptors play fundamental roles not only in physiological but also in pathological angiogenesis, characteristic of cancer progression. Aiming at finding putative treatments for several mal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ebb764609b9388ce263c5d756ab3a3c
http://hdl.handle.net/11591/435274
http://hdl.handle.net/11591/435274