Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Ettore, Lo Cascio"'
Autor:
Noah Giacon, Ettore Lo Cascio, Valeria Pennacchietti, Flavio De Maio, Giulia Santarelli, Diego Sibilia, Federica Tiberio, Maurizio Sanguinetti, Wanda Lattanzi, Angelo Toto, Alessandro Arcovito
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract The COVID-19 pandemic caused by SARS-CoV-2 has highlighted the urgent need for innovative antiviral strategies to fight viral infections. Although a substantial part of the overall effort has been directed at the Spike protein to create an e
Externí odkaz:
https://doaj.org/article/1ddadc7741ce42c7a61846415285a350
Autor:
Melinda Mariotti, Noah Giacon, Ettore Lo Cascio, Margherita Cacaci, Simona Picchietti, Maura Di Vito, Maurizio Sanguinetti, Alessandro Arcovito, Francesca Bugli
Publikováno v:
Pharmaceutics, Vol 16, Iss 9, p 1218 (2024)
Background: Functionalized nanoparticles (NPs) represent a cutting edge in innovative clinical approaches, allowing for the delivery of selected compounds with higher specificity in a wider time frame. They also hold promise for novel theranostic app
Externí odkaz:
https://doaj.org/article/11702858c0e94db7ac04f7a880388443
Autor:
Serena Brundu, Virginia Napolitano, Giulia Franzolin, Ettore Lo Cascio, Roberta Mastrantonio, Gabriele Sardo, Eliano Cascardi, Federica Verginelli, Sergio Sarnataro, Gennaro Gambardella, Alberto Pisacane, Alessandro Arcovito, Carla Boccaccio, Paolo M Comoglio, Enrico Giraudo, Luca Tamagnone
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 3, Pp 1-20 (2023)
Abstract The genetic changes sustaining the development of cancers of unknown primary (CUP) remain elusive. The whole‐exome genomic profiling of 14 rigorously selected CUP samples did not reveal specific recurring mutation in known driver genes. Ho
Externí odkaz:
https://doaj.org/article/987698c7f10d4c4294c18aba6c9e4084
Autor:
Noah Giacon, Ettore Lo Cascio, Darcy S. Davidson, Marcelo D. Polêto, Justin A. Lemkul, Valeria Pennacchietti, Livia Pagano, Carlotta Zamparelli, Angelo Toto, Alessandro Arcovito
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 3259-3271 (2023)
The Envelope (E) protein of SARS-CoV-2 plays a key role in virus maturation, assembly, and virulence mechanisms. The E protein is characterized by the presence of a PDZ-binding motif (PBM) at its C-terminus that allows it to interact with several PDZ
Externí odkaz:
https://doaj.org/article/5f87ea47f88e4bfda42747021ccdc226
Autor:
Ettore Lo Cascio, Angelo Toto, Gabriele Babini, Flavio De Maio, Maurizio Sanguinetti, Alvaro Mordente, Stefano Della Longa, Alessandro Arcovito
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 1838-1847 (2021)
Short Linear Motifs (SLiMs) are functional protein microdomains that typically mediate interactions between a short linear region in one protein and a globular domain in another. Surface Plasmon Resonance assays have been performed to determine the b
Externí odkaz:
https://doaj.org/article/bf96ef5a1f9242f290b6fa6905ec77aa
Autor:
Filomena, Lo Vecchio, Elisabetta, Tabolacci, Veronica, Nobile, Maria Grazia, Pomponi, Roberta, Pietrobono, Giovanni, Neri, Simona, Amenta, Ettore, Candida, Cristina, Grippaudo, Ettore, Lo Cascio, Alessia, Vita, Federica, Tiberio, Alessandro, Arcovito, Wanda, Lattanzi, Maurizio, Genuardi, Pietro, Chiurazzi
Publikováno v:
Genes. 13(7)
Craniosynostosis are a heterogeneous group of genetic conditions characterized by the premature fusion of the skull bones. The most common forms of craniosynostosis are Crouzon, Apert and Pfeiffer syndromes. They differ from each other in various add
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f75d85308b250c20b16399deb8440f68
https://pubmed.ncbi.nlm.nih.gov/35885943
https://pubmed.ncbi.nlm.nih.gov/35885943
Autor:
Flavio De Maio, Alessandro Arcovito, Alvaro Mordente, Ettore Lo Cascio, Gabriele Babini, Maurizio Sanguinetti, Angelo Toto, Stefano Della Longa
Publikováno v:
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 1838-1847 (2021)
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 1838-1847 (2021)
Graphical abstract
Short Linear Motifs (SLiMs) are functional protein microdomains that typically mediate interactions between a short linear region in one protein and a globular domain in another. Surface Plasmon Resonance assays have been perf
Short Linear Motifs (SLiMs) are functional protein microdomains that typically mediate interactions between a short linear region in one protein and a globular domain in another. Surface Plasmon Resonance assays have been perf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdfddd99e4c579f362e5511c4093fcc5
http://hdl.handle.net/11573/1536463
http://hdl.handle.net/11573/1536463
Autor:
Erika Marzola, Chiara Ruzza, Davide Illuminati, Salvatore Pacifico, Delia Preti, Claudio Trapella, Davide Malfacini, Ettore Lo Cascio, Valentina Albanese, Martina Marangoni, Remo Guerrini, Alessandro Arcovito, Martina Fabbri, Davide Fattori, Victor A D Holanda, Romina Nassini, Chiara Sturaro, Girolamo Calò, Federica Ferrari, Stefano Della Longa
Publikováno v:
Journal of Medicinal Chemistry
The nociceptin/orphanin FQ (N/OFQ)/N/OFQ receptor (NOP) system controls different biological functions including pain and cough reflex. Mixed NOP/opioid receptor agonists elicit similar effects to strong opioids but with reduced side effects. In this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::389d0e55aa9b9f3b2301fbd14216815d
http://hdl.handle.net/11697/183180
http://hdl.handle.net/11697/183180
Autor:
Ettore Lo Cascio, Gabriele Babini, Giovanni Scambia, Paola Roncada, Maurizio Sanguinetti, Alessandro Arcovito, Michela Sali, Flavio De Maio, Stefano Della Longa, Andrea Urbani, Bruno Tilocca
Publikováno v:
Microbes and Infection
The Envelope (E) protein of SARS-CoV-2 is the most enigmatic protein among the four structural ones. Most of its current knowledge is based on the direct comparison to the SARS E protein, initially mistakenly undervalued and subsequently proved to be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cc9dcd5239eaa2997d2d725583be11e
https://pubmed.ncbi.nlm.nih.gov/32891874
https://pubmed.ncbi.nlm.nih.gov/32891874