The cost impact of unselective vs selective MammaPrint testing in early-stage breast cancer in Southern Africa

Autor: Ettienne J. Myburgh, Josephus J. de Jager, Elizabeth Murray, Kathleen A. Grant, Maritha J. Kotze, Hermanus de Klerk

Publikováno v: Breast, Vol 59, Iss , Pp 87-93 (2021)

Background: MammaPrint (MP) has been applied in South Africa (SA) for decision-making in early-stage hormone receptor-positive breast cancer since 2006. The cost-impact of MP in SA has not been assessed. Aim: To assess different MP testing strategies

Externí odkaz: https://doaj.org/article/d4fad26a9c5d4335ba80e0cb0022e009

Clinical Overestimation of HER2 Positivity in Early Estrogen and Progesterone Receptor–Positive Breast Cancer and the Value of Molecular Subtyping Using BluePrint

Autor: Ettienne J. Myburgh, Lizanne Langenhoven, Kathleen A. Grant, Lize van der Merwe, Maritha J. Kotze

Publikováno v: Journal of Global Oncology, Vol 3, Iss 4, Pp 314-322 (2017)

Purpose: Human epidermal growth factor receptor 2 (HER2) positivity is an important prognostic and predictive indicator in breast cancer. HER2 status is determined by immunohistochemistry and fluorescent in situ hybridization (FISH), which are potent

Externí odkaz: https://doaj.org/article/c8226779257748b7a071ef8eee753f9e

Globally Rare BRCA2 Variants With Founder Haplotypes in the South African Population: Implications for Point-of-Care Testing Based on a Single-Institution BRCA1/2 Next-Generation Sequencing Study

Autor: Nerina C. van der Merwe, Ettienne J. Myburgh, Phillip Bester, Jaco Oosthuizen, Maritha J. Kotze, Nicole van der Merwe

Publikováno v: Frontiers in Oncology, Vol 10 (2021)

Breast cancer patients historically benefitted from population-based genetic research performed in South Africa, which led to the development of founder-based BRCA1/2 diagnostic tests. With the advent of next-generation sequencing (NGS) technologies,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f015d98b9ecd18b5bae90d60d63a0d8a

Globally Rare

Autor: Jaco, Oosthuizen, Maritha J, Kotze, Nicole, Van Der Merwe, Ettienne J, Myburgh, Phillip, Bester, Nerina C, van der Merwe

Publikováno v: Frontiers in Oncology

Breast cancer patients historically benefitted from population-based genetic research performed in South Africa, which led to the development of founder-based BRCA1/2 diagnostic tests. With the advent of next-generation sequencing (NGS) technologies,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8a60dbc16c2c43253fa9b8e9aa9c4370
https://pubmed.ncbi.nlm.nih.gov/33643918

Experiences of women in survivorship following mastectomy in the Cape Metropole

Autor: Ettienne J. Myburgh, M A Cohen, Nicole E Stecher

Publikováno v: South African Journal of Surgery, Volume: 57, Issue: 1, Pages: 19-23, Published: MAR 2019
South African Journal of Surgery; Vol. 57 No. 1 (2019); 19-23

Background: In spite of significant improvements in the treatment of breast cancer, many women still undergo mastectomy. The effects of breast cancer surgery on the diverse population of South African women have not been well studied. Insight may be

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcc3101bd1d8064a61c9b010a09e8f46
http://www.scielo.org.za/scielo.php?script=sci_arttext&pid=S0038-23612019000100004&lng=en&tlng=en