Artonin E induces p53-independent G1 cell cycle arrest and apoptosis through ROS-mediated mitochondrial pathway and livin suppression in MCF-7 cells

Autor: Etti IC, Rasedee A, Hashim NM, Abdul AB, Kadir A, Yeap SK, Waziri P, Malami I, Lim KL, Etti CJ

Publikováno v: Drug Design, Development and Therapy, Vol Volume11, Pp 865-879 (2017)

Imaobong Christopher Etti,1,2 Abdullah Rasedee,3 Najihah Mohd Hashim,4 Ahmad Bustamam Abdul,5 Arifah Kadir,6 Swee Keong Yeap,7 Peter Waziri,5 Ibrahim Malami,5 Kian Lam Lim,8 Christopher J Etti9 1Pharmacology and Toxicology, Faculty of Veterinary Medi

Externí odkaz: https://doaj.org/article/5879741041ce40ae974c36a14a1eca6e

5,6-dehydrokawain from the rhizome of Alpinia mutica Roxb. induced proangiogenic tumour-derived VEGF of HT-29 colorectal cancer.

Autor: Malami I; a Faculty of Pharmaceutical Sciences, Department of Pharmacognosy and Ethnopharmacy , Usmanu Danfodiyo University , Sokoto , Nigeria., Muhammad A; b Faculty of Life Sciences, Department of Biochemistry , Ahmadu Bello University , Zaria , Nigeria., Abubakar IB; c Department of Biochemistry , Kebbi State University , Aliero , Nigeria., Etti IC; d Department of Pharmacology and Toxicology , University of Uyo , Uyo , Nigeria., Waziri PM; e Department of Biochemistry , Kaduna State University , Kaduna , Nigeria., Abubakar RM; f Faculty of Pharmaceutical Sciences, Department of Pharmacology and Toxicology , Usmanu Danfodiyo University , Sokoto , Nigeria., Mshelia HE; a Faculty of Pharmaceutical Sciences, Department of Pharmacognosy and Ethnopharmacy , Usmanu Danfodiyo University , Sokoto , Nigeria.

Publikováno v: Natural product research [Nat Prod Res] 2018 Dec; Vol. 32 (24), pp. 2964-2967. Date of Electronic Publication: 2017 Oct 20.

An in silico approach in predicting the possible mechanism involving restoration of wild-type p53 functions by small molecular weight compounds in tumor cells expressing R273H mutant p53.

Autor: Malami I; Faculty of Pharmaceutical Sciences, Usmanu Danfodiyo University, Sokoto, Nigeria., Muhammad A; Department of Biochemistry, Faculty of Life Sciences, Ahmadu Bello University, Zaria, Nigeria., Etti IC; Department of Pharmacology and Toxicology, Universiti of Uyo, Uyo, Nigeria., Waziri PM; Department of Biochemistry, Kaduna State University, Kaduna, Nigeria., Alhassan AM; Faculty of Pharmaceutical Sciences, Usmanu Danfodiyo University, Sokoto, Nigeria.

Publikováno v: EXCLI journal [EXCLI J] 2017 Dec 08; Vol. 16, pp. 1276-1287. Date of Electronic Publication: 2017 Dec 08 (Print Publication: 2017).

The molecular mechanism of the anticancer effect of Artonin E in MDA-MB 231 triple negative breast cancer cells.

Autor: Etti IC; Pharmacology and Toxicology, Faculty of Veterinary Medicine, Universiti Putra Malaysia, Selangor, Malaysia.; Department of Pharmacology and Toxicology, University of Uyo, Uyo, Nigeria., Abdullah R; Department of Veterinary Pathology and Microbiology, Faculty of Veterinary Medicine, University Putra Malaysia, Selangor, Malaysia., Kadir A; Department of Veterinary Preclinical Science, Faculty of Veterinary Medicine, Universiti Putra Malaysia, Selangor, Malaysia., Hashim NM; Department of Pharmacy, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia., Yeap SK; Laboratory of Vaccine and Immunotherapeutics, Institute of Bioscience, University Putra Malaysia, Selangor, Malaysia., Imam MU; School of Public Health, Zhengzhou University, Zhengzhou city, Henan Province, PR China., Ramli F; Institute of Bioproduct Development, Universiti Technologyi Malaysia, Johor, Malaysia., Malami I; MAKNA-Cancer Research Laboratory, Institute of Bioscience, Universiti Putra Malaysia, Selangor, Malaysia., Lam KL; Faculty of Medicine and Health Sciences, Universiti Tunku Abdul Rahman, Selangor, Malaysia., Etti U; Department of Biochemistry, Obafemi Awolowo University, Ile Ife, Nigeria., Waziri P; MAKNA-Cancer Research Laboratory, Institute of Bioscience, Universiti Putra Malaysia, Selangor, Malaysia., Rahman M; Department of Pharmacy, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.

Publikováno v: PloS one [PLoS One] 2017 Aug 03; Vol. 12 (8), pp. e0182357. Date of Electronic Publication: 2017 Aug 03 (Print Publication: 2017).

Crude Extracts, Flavokawain B and Alpinetin Compounds from the Rhizome of Alpinia mutica Induce Cell Death via UCK2 Enzyme Inhibition and in Turn Reduce 18S rRNA Biosynthesis in HT-29 Cells.

Autor: Malami I; Laboratory of MAKNA-Cancer Research, Institute of Bioscience, Universiti Putra Malaysia Serdang, Selangor, Malaysia.; Department of Pharmacognosy and Ethnopharmacy, Faculty of Pharmaceutical Sciences, Usmanu Danfodiyo University, Sokoto, Nigeria., Abdul AB; Laboratory of MAKNA-Cancer Research, Institute of Bioscience, Universiti Putra Malaysia Serdang, Selangor, Malaysia.; Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Selangor, Malaysia., Abdullah R; Department of Veterinary Pathology and Microbiology, Faculty of Veterinary Medicine, Universiti Putra Malaysia Serdang, Selangor, Malaysia., Kassim NK; Department of Chemistry, Faculty of Science, Universiti Putra Malaysia Serdang, Selangor, Malaysia., Rosli R; Laboratory of MAKNA-Cancer Research, Institute of Bioscience, Universiti Putra Malaysia Serdang, Selangor, Malaysia.; Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Selangor, Malaysia., Yeap SK; Laboratory of Vaccine and Immunotherapeutics, Institute of Bioscience, Universiti Putra Malaysia Serdang, Selangor, Malaysia., Waziri P; Laboratory of MAKNA-Cancer Research, Institute of Bioscience, Universiti Putra Malaysia Serdang, Selangor, Malaysia., Etti IC; Department of Pharmacology and Toxicology, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia Serdang, Selangor, Malaysia., Bello MB; Department of Pharmacology and Toxicology, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia Serdang, Selangor, Malaysia.

Publikováno v: PloS one [PLoS One] 2017 Jan 19; Vol. 12 (1), pp. e0170233. Date of Electronic Publication: 2017 Jan 19 (Print Publication: 2017).