Mosaic and mixed HIV-1 glycoprotein nanoparticles elicit antibody responses to broadly neutralizing epitopes.

Autor: Brinkkemper M; Amsterdam UMC, location University of Amsterdam, Department of Medical Microbiology and Infection prevention, Amsterdam, The Netherlands.; Amsterdam institute for Infection and Immunity, Infectious diseases, Amsterdam, The Netherlands., Kerster G; Amsterdam UMC, location University of Amsterdam, Department of Medical Microbiology and Infection prevention, Amsterdam, The Netherlands.; Amsterdam institute for Infection and Immunity, Infectious diseases, Amsterdam, The Netherlands., Brouwer PJM; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, United States of America., Tran AS; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, United States of America., Torres JL; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, United States of America., Ettema RA; Amsterdam UMC, location University of Amsterdam, Department of Medical Microbiology and Infection prevention, Amsterdam, The Netherlands.; Amsterdam institute for Infection and Immunity, Infectious diseases, Amsterdam, The Netherlands., Nijhuis H; Amsterdam UMC, location University of Amsterdam, Department of Medical Microbiology and Infection prevention, Amsterdam, The Netherlands.; Amsterdam institute for Infection and Immunity, Infectious diseases, Amsterdam, The Netherlands., Allen JD; School of Biological Sciences, University of Southampton, Southampton, United Kingdom., Zhu W; School of Biological Sciences, University of Southampton, Southampton, United Kingdom., Gao H; Duke Human Vaccine Institute and Department of Surgery, Duke University Medical Center, Durham, North Carolina, United States of America., Lee WH; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, United States of America., Bijl TPL; Amsterdam UMC, location University of Amsterdam, Department of Medical Microbiology and Infection prevention, Amsterdam, The Netherlands.; Amsterdam institute for Infection and Immunity, Infectious diseases, Amsterdam, The Netherlands., Snitselaar JL; Amsterdam UMC, location University of Amsterdam, Department of Medical Microbiology and Infection prevention, Amsterdam, The Netherlands.; Amsterdam institute for Infection and Immunity, Infectious diseases, Amsterdam, The Netherlands., Burger JA; Amsterdam UMC, location University of Amsterdam, Department of Medical Microbiology and Infection prevention, Amsterdam, The Netherlands.; Amsterdam institute for Infection and Immunity, Infectious diseases, Amsterdam, The Netherlands., Bontjer I; Amsterdam UMC, location University of Amsterdam, Department of Medical Microbiology and Infection prevention, Amsterdam, The Netherlands.; Amsterdam institute for Infection and Immunity, Infectious diseases, Amsterdam, The Netherlands., Olijhoek W; Amsterdam UMC, location University of Amsterdam, Department of Medical Microbiology and Infection prevention, Amsterdam, The Netherlands.; Amsterdam institute for Infection and Immunity, Infectious diseases, Amsterdam, The Netherlands., Ravichandran R; Department of Biochemistry, University of Washington, Seattle, Washington, United States of America.; Institute for Protein Design, University of Washington, Seattle, Washington, United States of America., van Breemen MJ; Amsterdam UMC, location University of Amsterdam, Department of Medical Microbiology and Infection prevention, Amsterdam, The Netherlands.; Amsterdam institute for Infection and Immunity, Infectious diseases, Amsterdam, The Netherlands., Del Moral-Sánchez I; Amsterdam UMC, location University of Amsterdam, Department of Medical Microbiology and Infection prevention, Amsterdam, The Netherlands.; Amsterdam institute for Infection and Immunity, Infectious diseases, Amsterdam, The Netherlands., Derking R; Amsterdam UMC, location University of Amsterdam, Department of Medical Microbiology and Infection prevention, Amsterdam, The Netherlands.; Amsterdam institute for Infection and Immunity, Infectious diseases, Amsterdam, The Netherlands., Sliepen K; Amsterdam UMC, location University of Amsterdam, Department of Medical Microbiology and Infection prevention, Amsterdam, The Netherlands.; Amsterdam institute for Infection and Immunity, Infectious diseases, Amsterdam, The Netherlands., Ozorowski G; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, United States of America., Crispin M; School of Biological Sciences, University of Southampton, Southampton, United Kingdom., Montefiori DC; Duke Human Vaccine Institute and Department of Surgery, Duke University Medical Center, Durham, North Carolina, United States of America., Claireaux M; Amsterdam UMC, location University of Amsterdam, Department of Medical Microbiology and Infection prevention, Amsterdam, The Netherlands.; Amsterdam institute for Infection and Immunity, Infectious diseases, Amsterdam, The Netherlands., Ward AB; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, United States of America., van Gils MJ; Amsterdam UMC, location University of Amsterdam, Department of Medical Microbiology and Infection prevention, Amsterdam, The Netherlands.; Amsterdam institute for Infection and Immunity, Infectious diseases, Amsterdam, The Netherlands., King NP; Department of Biochemistry, University of Washington, Seattle, Washington, United States of America.; Institute for Protein Design, University of Washington, Seattle, Washington, United States of America., Sanders RW; Amsterdam UMC, location University of Amsterdam, Department of Medical Microbiology and Infection prevention, Amsterdam, The Netherlands.; Amsterdam institute for Infection and Immunity, Infectious diseases, Amsterdam, The Netherlands.; Department of Microbiology and Immunology, Weill Medical College of Cornell University, New York, New York, United States of America.

Publikováno v: PLoS pathogens [PLoS Pathog] 2024 Oct 03; Vol. 20 (10), pp. e1012558. Date of Electronic Publication: 2024 Oct 03 (Print Publication: 2024).