Zobrazeno 1 - 10
of 94
pro vyhledávání: '"Etsuko Wada"'
Publikováno v:
Journal of Pharmacological Sciences, Vol 110, Iss 2, Pp 127-132 (2009)
Abstract.: Early brain development has a tremendous impact on the success of humans throughout their lives. During early development, neural circuit formation proceeds in a strictly regulated manner. In addition to genetic and epigenetic programs, re
Externí odkaz:
https://doaj.org/article/3b8b030eaf584a03adf8808459ed9f27
Autor:
James E. Porter, Florian Lesage, Nicholas I. Cilz, Zhaoyang Xiao, Saobo Lei, Colin K. Combs, Chuanxiu Yang, Binqi Hu, Lalitha Kurada, Etsuko Wada
Publikováno v:
The Journal of Neuroscience. 34:7027-7042
Neurotensin (NT) is a tridecapeptide distributed in the CNS, including the entorhinal cortex (EC), a structure that is crucial for learning and memory and undergoes the earliest pathological alterations in Alzheimer's disease (AD). Whereas NT has bee
Publikováno v:
The American Journal of Chinese Medicine. 41:515-529
Toki-shakuyaku-san (TSS), an herbal formula based on traditional Chinese medicine, is commonly used in obstetrics. To examine the effects of TSS on the normal mouse fetus and placenta, TSS was administered to normal pregnant mice and their placentas
Autor:
Masaaki Yoshikawa, Etsuko Wada, Kousaku Ohinata, Ayako Yamada, Norimasa Kanegawa, Masayuki Sekiguchi, Ayako Oda, Chihiro Suzuki, Keiji Wada, Daisuke Yamada, I-ching Hou
Publikováno v:
Journal of Neurochemistry. 119:785-790
β-Lactotensin (His-Ile-Arg-Leu) is a bioactive peptide derived from bovine milk β-lactoglobulin, acting as a natural agonist for neurotensin receptors. We found that β-lactotensin exhibited anxiolytic-like activity in an elevated plus-maze test af
Publikováno v:
Pharmacology Biochemistry and Behavior. 96:363-369
Neurotensin is known to have antipsychotic-like behavioral and neurochemical effects, but its participation in fear memory has not been fully elucidated. Here, we report that a lack of type 1 neurotensin receptor (Ntsr1) increases the behavioral fear
Autor:
Karen Jesus Oliveira, Luana L. Souza, Etsuko Wada, Valeria de Mello-Coelho, Flavia Fonseca Bloise, Carmen C. Pazos-Moura, Gabriela S. M. Paula, Adriana Cabanelas, Tania M. Ortiga-Carvalho
Publikováno v:
The Journal of Physiology. 588:1635-1645
Previous studies have proposed a role for neuromedin B (NB), a bombesin-like peptide, in the control of body weight homeostasis. However, the nature of this role is unclear. The actions of NB are mediated preferentially by NB-preferring receptors (NB
Publikováno v:
Neuroscience Letters. 454:28-32
The maternal environment is thought to be important for fetal brain development. However, the effects of maternal environment are not fully understood. Here, we investigated whether enrichment of the maternal environment can influence prenatal brain
Publikováno v:
Neurochemistry International. 54:222-228
Maternal bioactive substances, such as hormones and neuropeptides, are thought to be essential for fetal development. Recently, ghrelin, a gastrointestinal peptide, has been shown to pass through the rat placenta. The ghrelin receptor, growth hormone
Autor:
Adrian M. Piliponsky, Martin Metz, Eon J. Rios, Stephen J. Galli, Gunnar Pejler, Mindy Tsai, Ching-Cheng Chen, Ronald G. Pearl, Sherma Zacharias, James D. Faix, Uma M. Mohanasundaram, Keiji Wada, Paul R. Dobner, Toshihiko Nishimura, Magnus Åbrink, Etsuko Wada
Publikováno v:
Nature Medicine. 14:392-398
Sepsis is a complex, incompletely understood and often fatal disorder,1 typically accompanied by hypotension,2 that is considered to represent a dysregulated host response to infection.3,4,5 Neurotensin (NT) is a 13-amino-acid peptide that, among its
Autor:
Carmen C. Pazos-Moura, Marco Aurélio Liberato Costa da Veiga, Tania M. Ortiga-Carvalho, Karen Jesus Oliveira, Keiji Wada, Etsuko Wada, Gabriela S. M. Paula, Adriana Cabanelas
Publikováno v:
Regulatory Peptides. 146:213-217
Neuromedin B (NB), a neuropeptide highly concentrated in pituitary, has been proposed to be an inhibitor of thyrotropin (TSH) secretion. Previous study showed that mice with disruption of neuromedin B receptor (NBR-KO) have higher TSH release in resp