Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Etsuko Morihara"'
Autor:
Tomohiro Akagi, Supanee Duangteraprecha, Hiroshi Katayama, Motoyasu Honda, Kazuhisa Miyamoto, Kazumasa Hirata, Etsuko Morihara, Masuo Nakae
Publikováno v:
Biotechnology Letters. 19:53-57
Vinblastine (VLB) is an antineoplastic agent contained in leaves of Catharanthus roseus. One-pot synthesis of VLB from vindoline and catharanthine, biosynthetic precursors in the plant, was achieved under biomimetic conditions. FMN-mediated coupling
Autor:
Supanee Duangteraprecha, Etsuko Morihara, Kazumasa Hirata, Kazuhisa Miyamoto, Masuo Nakae, Motoyasu Honda, Hiroshi Katayama
Publikováno v:
Journal of Fermentation and Bioengineering. 83:227-232
Non-enzymic coupling of vindoline and catharanthine to synthesize the dihydropyridinium intermediate (DHPI) of dimeric alkaloids was achieved under near-ultraviolet light irradiation with a peak at 370 nm in the presence of flavin mononucleotide (FMN