Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Etsuko Kushiya"'
Autor:
Kenji Sakimura, Manabu Abe, Etsuko Kushiya, Kaori Akashi, Masahiro Fukaya, Haruyuki Kamiya, Mika Tsujita, Maya Yamazaki, Rie Natsume, Masahiko Watanabe, Masanobu Kano
Publikováno v:
European Journal of Neuroscience. 24(8):2177-2190
Transmembrane alpha-amino-3-hydroxyl-5-isoxazolepropionate (AMPA) receptor regulatory proteins (TARPs) play pivotal roles in AMPA receptor trafficking and gating. Here we examined cellular and subcellular distribution of TARP gamma-8 in the mouse bra
Autor:
Jun Tanaka, Etsuko Kushiya, Melvin I. Simon, Kenji Sakimura, Masanobu Kano, Masahiro Fukaya, Shin Nakagawa, Toshihiko Iwanaga, Miwako Yamasaki, Masahiko Watanabe
Publikováno v:
European Journal of Neuroscience. 12:781-792
Following cell surface receptor activation, the alpha subunit of the Gq subclass of GTP-binding proteins activates the phosphoinositide signalling pathway. Here we examined the expression and localization of Gq protein alpha subunits in the adult mou
Autor:
Takeshi Yagi, Masayoshi Mishina, Shima Toki, Toshiya Manabe, Masahiko Watanabe, Kenji Sakimura, Hisashi Mori, Kazuhiro Nakamura, Yasushi Satoh, Norimitsu Suzuki, Tomoyuki Takahashi, Etsuko Kushiya, Yoshiro Inoue
Publikováno v:
Neuron. 21(3):571-580
The synaptic localization of the N-methyl-D-aspartate (NMDA) type glutamate receptor (GluR) channel is a prerequisite for synaptic plasticity in the brain. We generated mutant mice carrying the carboxy-terminal truncated GluR epsilon2 subunit of the
Autor:
Yoshihisa Kudo, Yasuo Takahashi, Kenji Sakimura, Etsuko Kushiya, Akihiko Ogura, Takashi Katagiri
Publikováno v:
Molecular Brain Research. 28:19-28
Neuron-specific enolase (NSE) occurs in mature neurons and paraneurons. We have isolated the genomic clone coding for rat NSE and clarified its gene structure. In order to analyze the regulatory sequence in the 5'-upstream region and introns, we carr
Autor:
Kazutaka Ikeda, Hisashi Masaki, Hiroyuki Meguro, Masayoshi Mishina, Takao Morita, Etsuko Kushiya, Nobuko Kashiwabuchi, Tomohiro Yamakura, Hisashi Mori, Tatsuya Kutsuwada, Michiaki Nagasawa, Kazuaki Araki, Kenji Sakimura, Makoto Yamazaki
Publikováno v:
Annals of the New York Academy of Sciences. 707:136-152
Autor:
Kazuaki Araki, Masayoshi Mishina, Hiroyuki Meguro, Takao Morita, Kenji Sakimura, Etsuko Kushiya, Kazuhiro J. Mori, Teruo Abe, Masatoshi Yamazaki
Publikováno v:
Molecular Brain Research. 14:143-146
The primary structure of the mouse glutamate receptor beta 2 subunit has been deduced by cloning and sequencing cDNA. The beta 2 subunit has structural characteristics common to the subunits of glutamate-gated ion channels. Expression of the cloned c
Autor:
Etsuko Kushiya, Shigeo Uchino, Hisashi Mori, Masayoshi Mishina, Kenji Sakimura, Kenji Nagahari, Masayuki Harabayashi
Publikováno v:
Biochemical and Biophysical Research Communications. 180:813-821
Summary Functional analysis of AMPA-selective glutamate receptor channels expressed in Xenopus oocytes from cloned cDNAs has shown that homomeric channels formed by the G1uR1 subunit are permeable to Ca2+, whereas heteromeric channels composed of the
Publikováno v:
FEBS Letters. 277:78-82
The structure of rat muscle-specific enolase (beta beta enolase) gene was determined. It comprises 12 exons of various lengths (59-223 bp) spanning about 6 kbp and its exon-intron organization is similar to that of neuron-specific enolase (gamma gamm
Autor:
Tatsuya Kutsuwada, Hiroyuki Sugiyama, Toshiya Manabe, Masayoshi Mishina, Yoshiro Inoue, Chitoshi Takayama, Etsuko Kushiya, Kenji Sakimura, Shinichi Aizawa, Takeshi Yagi, Isao Ito
Publikováno v:
Nature. 373(6510)
The NMDA (N-methyl-D-aspartate) receptor channel is important for synaptic plasticity, which is thought to underlie learning, memory and development. The NMDA receptor channel is formed by at least two members of the glutamate receptor (GluR) channel
Autor:
Etsuko Kushiya, Masaaki Arakawa, Tatsuya Kutsuwada, Masayoshi Mishina, Hiroyuki Meguro, Nobuko Kashiwabuchi, Kazuaki Araki, Toshiro Kumanishi, Hisashi Mori, Hisashi Masaki, Kenji Sakimura
Publikováno v:
Nature. 358(6381)
Two novel subunits of the mouse NMDA receptor channel, the epsilon 2 and epsilon 3 subunits, have been identified by cloning and expression of complementary DNAs. The heteromeric epsilon 1/zeta 1, epsilon 2/zeta 1 and epsilon 3/zeta 1 NMDA receptor c