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pro vyhledávání: '"Etsuji Kaneko"'
Autor:
Etsuji Kaneko
Publikováno v:
Drug Delivery System. 38:49-57
Publikováno v:
Monoclonal Antibodies in Immunodiagnosis and Immunotherapy. 41:125-132
Therapeutic agents targeting B cells, such as rituximab, have been proven to be effective in several diseases. However, since this therapy targets the whole B cell population, there are still concerns about critical adverse events. Therefore, a new t
Autor:
Etsuji Kaneko, Hiroaki Ito, Shinji Katsushima, Risa Watanabe, Kenichi Furihata, Takuya Morishige, Munetake Shimabe, Yoh Ishiguro, Mayumi Mukai, Naoki Yoshimura
Publikováno v:
Clinical Pharmacology in Drug Development
OX40 plays an essential role in maintaining late T‐cell proliferation and survival by suppressing apoptosis and by inducing T‐cell memory formation. Here, we report the results of the phase 1 study of KHK4083, a fully human antimonoclonal antibod
Autor:
Etsuji Kaneko
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. 95:2-S23
Publikováno v:
Journal of Bioscience and Bioengineering. 113:641-646
Gene therapy has been regarded as an innovative potential treatment against serious congenital diseases. However, applications of gene therapy remain limited, partly because its clinical success depends on therapeutic gene-transduced cells acquiring
Autor:
Yasuhiko Tomino, Naoko Hiura, Hiroyuki Yanagawa, Yusuke Suzuki, Yuko Makita, Etsuji Kaneko, Hitoshi Suzuki, Junichi Yasutake
Publikováno v:
Nephrology Dialysis Transplantation
Background Galactose-deficient IgA1 (Gd-IgA1) is a critical effector molecule in the pathogenesis of IgA nephropathy (IgAN). Although many researchers have measured serum levels of Gd-IgA1 using snail helix aspersa agglutinin (HAA) lectin-based assay
Autor:
Teruyuki Nagamune, Hiroshi Ueda, Etsuji Kaneko, Kouhei Tsumoto, Masahiro Kawahara, Izumi Kumagai
Publikováno v:
JOURNAL OF CHEMICAL ENGINEERING OF JAPAN. 37:1259-1264
Previously, we proposed the Antigen-mediated genetically modified cell amplification (AMEGA) system, which can selectively amplify gene-transduced cells without antibiotic selection. While the original AMEGA system employed two vectors encoding a pai
Autor:
Etsuji Kaneko, Breeanna Gibson, Zimin Sun, Lijun Xia, J. Michael McDaniel, Leonard P. Miller, Jean Goodman, Padmaja Mehta-D’souza, Mikhail G. Dozmorov, Yuesi Wang, Xiang Wan, Yiyuan Chen, Hiromasa Miyaji, Hidetaka Sato
Publikováno v:
Glycobiology. 23(10)
Selectins and their carbohydrate ligands mediate the homing of hematopoietic stem/progenitor cells (HSPCs) to the bone marrow. We have previously shown that ex vivo fucosylation of selectin ligands on HSPCs by α1,3 fucosyltransferase VI (FUT6) leads
Autor:
Junichi Yasutake, Yusuke Suzuki, Hitoshi Suzuki, Naoko Hiura, Hiroyuki Yanagawa, Yuko Makita, Etsuji Kaneko, Yasuhiko Tomino
Publikováno v:
Nephrology Dialysis Transplantation; Aug2015, Vol. 30 Issue 8, p1315-1321, 7p, 1 Color Photograph, 1 Chart, 4 Graphs