The multikinase inhibitor Sorafenib displays significant antiproliferative effects and induces apoptosis via caspase 3, 7 and PARP in B- and T-lymphoblastic cells

Autor: Boldt Sonja, Fuellen Georg, Glass Aenne, Etro Daniela, Lange Sandra, Amoroso Francesca, Sawitzky Mandy, Ruck Sabine, Dahlhaus Meike, Schult Catrin, Wolkenhauer Olaf, Neri Luca, Freund Mathias, Junghanss Christian

Publikováno v: BMC Cancer, Vol 10, Iss 1, p 560 (2010)

Abstract Background Targeted therapy approaches have been successfully introduced into the treatment of several cancers. The multikinase inhibitor Sorafenib has antitumor activity in solid tumors and its effects on acute lymphoblastic leukemia (ALL)

Externí odkaz: https://doaj.org/article/951288d6987341d8b4297d10f4e64910

Thrombosis in inherited factor VII deficiency

Autor: Mariani, G, Herrmann, Fh, Schulman, S, Batorova, A, Wulff, K, Etro, Daniela, Dolce, A, Auerswald, G, Astermark, J, Schved, Jf, Ingerslev, J, Bernardi, Francesco, INTERNATIONAL FACTOR VII DEFICIENCY STUDY GROUP

Publikováno v: Journal of Thrombosis and Haemostasis. 1:2153-2158

Thrombosis in congenital factor (F) VII deficiency was investigated through extensive phenotypic and molecular-genetic studies. Patients with a history of thrombosis among 514 entries in the FVII Deficiency Study Group database were evaluated. Thromb

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4eccebf64b5f9bc3efb5b87b58af29a8
https://doi.org/10.1046/j.1538-7836.2003.00395.x

The erythroid differentiation of K562 cells depends on the nuclear translocation of Akt

Autor: Missiroli, Silvia, Etro, Daniela, Neri, Luca Maria, Capitani, Silvano

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3709::cf9c1fe8b95ceab40e72228756d143a8
http://hdl.handle.net/11392/521498

Clinical phenotypes and factor VII genotype in congenital factor VII deficiency

Autor: Mariani, G, Herrmann, Fh, Dolce, A, Batorova, A, Etro, Daniela, Peyvandi, F, Wulff, K, Schved, Jf, Auerswald, G, Ingerslev, J, Bernardi, Francesco, INTERNATIONAL FACTOR VII DEFICIENCY STUDY GROUP

Publikováno v: Mariani, G, Hermann, FH, Docle, A, Batorova, A, Etro, D, Peynandi, F, Wulff, K, Schved, JF, Auerswald, G, Ingerslev, J & Bernardi, F 2005, ' Clinical phenotypes and factor VII genotype in congenital factor VII deficiency ', Thromb. Haemost., vol. 93, pp. 481-487 .

SummaryTo investigate the relationship between clinical phenotype, clotting activity (FVIIc) and FVII genotype, a multi-center study of factor VII (FVII) congenital deficiency with centralized genotyping and specific functional assays was carried out

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c8dd1230dc586ecafa7e681568701f7
https://pubmed.ncbi.nlm.nih.gov/15735798

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