Zobrazeno 1 - 10
of 556
pro vyhledávání: '"Etienne-Emile Baulieu"'
Autor:
Emilie Lesport, Lucie Commeau, Mélanie Genet, Etienne-Emile Baulieu, Marcel Tawk, Julien Giustiniani
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 18 (2024)
The failure of the autophagy-lysosomal pathway to clear the pathogenic forms of Tau exacerbates the pathogenesis of tauopathies. We have previously shown that the immunophilin FKBP52 interacts both physically and functionally with Tau, and that a dec
Externí odkaz:
https://doaj.org/article/51a5cd0174404aa1b1f736aa034c62c1
Autor:
Francesca Farina, Emmanuel Lambert, Lucie Commeau, François-Xavier Lejeune, Nathalie Roudier, Cosima Fonte, J. Alex Parker, Jacques Boddaert, Marc Verny, Etienne-Emile Baulieu, Christian Neri
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
Abstract Helping neurons to compensate for proteotoxic stress and maintain function over time (neuronal compensation) has therapeutic potential in aging and neurodegenerative disease. The stress response factor FOXO3 is neuroprotective in models of H
Externí odkaz:
https://doaj.org/article/6708c811da8d48d8a864bd74cd34faa5
Autor:
Etienne-Emile Baulieu
Publikováno v:
Frontiers in Endocrinology, Vol 9 (2018)
Some newly described steroid-related compounds, also found in the rest of the body, are formed and active in the central nervous system, particularly in the brain. Some are of pharmacological and physiopathological interest. We specifically report on
Externí odkaz:
https://doaj.org/article/c4e1177c38304206af3a34ccda8845a1
Autor:
Philippe Liere, Antoine Pianos, Bernard Eychenne, Annie Cambourg, Karl Bodin, William Griffiths, Michael Schumacher, Etienne-Emile Baulieu, Jan Sjövall
Publikováno v:
Journal of Lipid Research, Vol 50, Iss 12, Pp 2430-2444 (2009)
Pregnenolone (PREG) and dehydroepiandrosterone (DHEA), and their respective sulfated forms PREGS and DHEAS, were among the first steroids to be identified in rodent brain. However, unreliable steroid isolation and solvolysis procedures resulted in er
Externí odkaz:
https://doaj.org/article/d41b36d12b3a42cc855c631fcb8e3287
Autor:
Philippe Liere, Antoine Pianos, Bernard Eychenne, Annie Cambourg, Suya Liu, William Griffiths, Michael Schumacher, Jan Sjövall, Etienne-Emile Baulieu
Publikováno v:
Journal of Lipid Research, Vol 45, Iss 12, Pp 2287-2302 (2004)
A new sample preparation method coupled to GC-MS analysis was developed and validated for quantification of sulfate esters of pregnenolone (PREG-S) and dehydroepiandrosterone (DHEA-S) in rat brain. Using a solid-phase extraction recycling protocol, t
Externí odkaz:
https://doaj.org/article/f2b8398e7a444ea494bb141885cc443f
Autor:
Geri Meduri, Kevin Guillemeau, Corentin Daguinot, Omar Dounane, Melanie Genet, Luigi Ferrara, Beatrice Chambraud, Etienne Emile Baulieu, Julien Giustiniani
Publikováno v:
Journal of Alzheimer's Disease. :1-19
Background: Pathological tau proteins constitute neurofibrillary tangles that accumulate in tauopathies including Alzheimer’s disease (AD), progressive supranuclear palsy (PSP), and familial frontotemporal lobar degeneration (FTLD-Tau). We previous
Autor:
Kevin Guillemeau, Béatrice Chambraud, Julien Giustiniani, Etienne-Emile Baulieu, Christian Poüs, Geri Meduri, Omar Dounane, Melanie Genet, Corentin Daguinot
Publikováno v:
Autophagy
Defects of autophagy-lysosomal protein degradation are thought to contribute to the pathogenesis of several neurodegenerative diseases, and the accumulation of aggregation prone proteins such as MAPT/Tau in Alzheimer disease (AD). We previously showe
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, 2022, 23 (3), pp.1738. ⟨10.3390/ijms23031738⟩
International Journal of Molecular Sciences, Vol 23, Iss 1738, p 1738 (2022)
International Journal of Molecular Sciences, 2022, 23 (3), pp.1738. ⟨10.3390/ijms23031738⟩
International Journal of Molecular Sciences, Vol 23, Iss 1738, p 1738 (2022)
International audience; The FK506-binding protein 52 (FKBP52) belongs to a large family of ubiquitously expressed and highly conserved proteins (FKBPs) that share an FKBP domain and possess Peptidyl-Prolyl Isomerase (PPIase) activity. PPIase activity
Autor:
Martine El-Etr, Jérôme De Seze, Patrick Hautecoeur, Françoise Durand-Dubief, Jean Pelletier, Etienne-Emile Baulieu, Francesco Patti, David-Axel Laplaud, L. Gignoux, Maria Trojano, Emmanuelle Le Page, Sandra Vukusic, Pierre Clavelou, Luca Durelli, Iuliana Ionescu, David Brassat, Eric Berger, Catherine Cornu, Laurent Remontet, Nadine Bossard, Giovanni Castelnovo, Marc Debouverie, François Cotton, Olivier Heinzlef, Romain Marignier, Thibault Moreau, Christine Lebrun-Frenay
Publikováno v:
Multiple Sclerosis Journal
Multiple Sclerosis Journal, 2021, 27 (9), pp.1458-1463. ⟨10.1177/1352458520978218⟩
Multiple Sclerosis Journal, SAGE Publications, 2020, pp.135245852097821. ⟨10.1177/1352458520978218⟩
Multiple Sclerosis Journal, SAGE Publications, 2021, 27 (9), pp.1458-1463. ⟨10.1177/1352458520978218⟩
Multiple Sclerosis Journal, 2021, 27 (9), pp.1458-1463. ⟨10.1177/1352458520978218⟩
Multiple Sclerosis Journal, SAGE Publications, 2020, pp.135245852097821. ⟨10.1177/1352458520978218⟩
Multiple Sclerosis Journal, SAGE Publications, 2021, 27 (9), pp.1458-1463. ⟨10.1177/1352458520978218⟩
Background: Sex steroids could explain the course of multiple sclerosis (MS) in pregnancy. Objective: To compare the annualized relapse rate (ARR) 12 weeks post-partum in women treated with nomegestrol acetate (NOMAc) and 17-beta-estradiol (E2) versu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70d02443f8900e3ea09454ff58b38197
https://hal.science/hal-03101890
https://hal.science/hal-03101890
Publikováno v:
Pharmacology & Therapeutics. 191:190-206
Neurosteroids are neuroactive brain-born steroids. They can act through non-genomic and/or through genomic pathways. Genomic pathways are largely described for steroid hormones: the binding to nuclear receptors leads to transcription regulation. Preg