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Autor:
Linda B. S. Aulin, Sebastian T. Tandar, Torben van Zijp, Etienne van Ballegooie, Piet H. van der Graaf, Mohammed A. A. Saleh, Pyry Välitalo, J. G. Coen van Hasselt
Publikováno v:
Clinical Pharmacokinetics, 61, 1735-1748
Prediction of antimicrobial target-site pharmacokinetics is of relevance to optimize treatment with antimicrobial agents. A physiologically based pharmacokinetic (PBPK) model framework was developed for prediction of pulmonary pharmacokinetics, inclu