Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Etienne Meylan"'
Autor:
Julien Faget, Etienne Meylan, Katarina Pinjusic, Olivier Andreas Dubey, Olga Egorova, Sina Nassiri, Daniel Beat Constam
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 5 (2022)
Externí odkaz:
https://doaj.org/article/df12df2c91894f59bd4cbb8de01c1c8f
Autor:
Gael Boivin, Julien Faget, Pierre-Benoit Ancey, Aspasia Gkasti, Julie Mussard, Camilla Engblom, Christina Pfirschke, Caroline Contat, Justine Pascual, Jessica Vazquez, Nathalie Bendriss-Vermare, Christophe Caux, Marie-Catherine Vozenin, Mikael J. Pittet, Matthias Gunzer, Etienne Meylan
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Anti-Ly6G or ant-Gr1 antibodies are commonly used to deplete neutrophils in vivo. Here the authors provide mechanistic insight into why these approaches may not specifically or durably reduce the number of neutrophils in mice, and also present a new
Externí odkaz:
https://doaj.org/article/d3653b7e42a14239a9541459d01f0ce4
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 7 (2021)
The immune checkpoint blockade-based immunotherapies are revolutionizing cancer management. Tumor-associated neutrophils (TANs) were recently highlighted to have a pivotal role in modulating the tumor microenvironment and the antitumor immune respons
Externí odkaz:
https://doaj.org/article/897f533c671142b191c8ebe352e3f2a4
Autor:
Gaël Boivin, Pierre-Benoit Ancey, Romain Vuillefroy de Silly, Pradeep Kalambaden, Caroline Contat, Benoit Petit, Jonathan Ollivier, Jean Bourhis, Etienne Meylan, Marie-Catherine Vozenin
Publikováno v:
OncoImmunology, Vol 10, Iss 1 (2021)
The anti-Ly6G antibody is used to deplete Ly6Gpos neutrophils and study their role in diverse pathologies. However, depletion is never absolute, as Ly6Glow neutrophils resistant to depletion rapidly emerge. Studying the functionality of these residua
Externí odkaz:
https://doaj.org/article/d859437683ad47369e5adee3a49c5195
Autor:
Christina Pfirschke, Camilla Engblom, Jeremy Gungabeesoon, Yunkang Lin, Steffen Rickelt, Rapolas Zilionis, Marius Messemaker, Marie Siwicki, Genevieve M. Gerhard, Anna Kohl, Etienne Meylan, Ralph Weissleder, Allon M. Klein, Mikael J. Pittet
Publikováno v:
Cell Reports, Vol 32, Iss 12, Pp 108164- (2020)
Summary: Myeloid cells co-expressing the markers CD11b, Ly-6G, and SiglecF can be found in large numbers in murine lung adenocarcinomas and accelerate cancer growth by fostering tumor cell invasion, angiogenesis, and immunosuppression; however, some
Externí odkaz:
https://doaj.org/article/dc64c52451794ba69d2b5d595d53e806
Autor:
Caroline Contat, Pierre-Benoit Ancey, Nadine Zangger, Silvia Sabatino, Justine Pascual, Stéphane Escrig, Louise Jensen, Christine Goepfert, Bernard Lanz, Mario Lepore, Rolf Gruetter, Anouk Rossier, Sabina Berezowska, Christina Neppl, Inti Zlobec, Stéphanie Clerc-Rosset, Graham William Knott, Jeffrey C Rathmell, E Dale Abel, Anders Meibom, Etienne Meylan
Publikováno v:
eLife, Vol 9 (2020)
Glucose utilization increases in tumors, a metabolic process that is observed clinically by 18F-fluorodeoxyglucose positron emission tomography (18F-FDG-PET). However, is increased glucose uptake important for tumor cells, and which transporters are
Externí odkaz:
https://doaj.org/article/c3aba89d5d7741e7b31b5d7c0de19941
Autor:
Julien Faget, Svenja Groeneveld, Gael Boivin, Martial Sankar, Nadine Zangger, Miguel Garcia, Nicolas Guex, Inti Zlobec, Loïc Steiner, Alessandra Piersigilli, Ioannis Xenarios, Etienne Meylan
Publikováno v:
Cell Reports, Vol 21, Iss 11, Pp 3190-3204 (2017)
Understanding the immune compartment of tumors facilitates the development of revolutionary new therapies. We used a Kras(G12D)-driven mouse model of lung cancer to establish an immune signature and identified a contribution of Gr1+ neutrophils to di
Externí odkaz:
https://doaj.org/article/41248bbbba0546148e82ff48eaa672e0
Autor:
Gaël Boivin, Pradeep Kalambaden, Julien Faget, Sylvie Rusakiewicz, Pierre Montay-Gruel, Etienne Meylan, Jean Bourhis, Guy Lesec, Marie-Catherine Vozenin
Publikováno v:
Frontiers in Oncology, Vol 8 (2018)
Immune-based anti-cancer strategies combined with radiation therapy (RT) are actively being investigated but many questions remain, such as the ideal treatment scheme and whether a potent immune response can be generated both locally and systemically
Externí odkaz:
https://doaj.org/article/3ec8f00a0d8d49ce8631cdd869cc95f2
Autor:
Martin Etzrodt, Virna Cortez-Retamozo, Andita Newton, Jimmy Zhao, Aylwin Ng, Moritz Wildgruber, Pedro Romero, Thomas Wurdinger, Ramnik Xavier, Frederic Geissmann, Etienne Meylan, Matthias Nahrendorf, Filip K. Swirski, David Baltimore, Ralph Weissleder, Mikael J. Pittet
Publikováno v:
Cell Reports, Vol 1, Iss 4, Pp 317-324 (2012)
Monocytes serve as a central defense system against infection and injury but can also promote pathological inflammatory responses. Considering the evidence that monocytes exist in at least two subsets committed to divergent functions, we investigated
Externí odkaz:
https://doaj.org/article/219d87c7f6b94359a6887a828de5218b
Inhaled dry powder cisplatin increases antitumour response to anti-PD1 in a murine lung cancer model
Autor:
Tamara Davenne, Pauline Percier, Lionel Larbanoix, Muriel Moser, Oberdan Leo, Etienne Meylan, Stanislas Goriely, Pierre Gérard, Nathalie Wauthoz, Sophie Laurent, Karim Amighi, Rémi Rosière
Publikováno v:
Journal of Controlled Release. 353:317-326
Despite advances in targeted therapies and immunotherapy in lung cancer, chemotherapy remains the backbone of treatment in most patients at different stages of the disease. Inhaled chemotherapy is a promising strategy to target lung tumours and to li