Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Etienne Leygue"'
Autor:
Lucas E. L. Terceiro, Nnamdi M. Ikeogu, Matheus F. Lima, Chidalu A. Edechi, Barbara E. Nickel, Gabor Fischer, Etienne Leygue, Kirk J. McManus, Yvonne Myal
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 15, p 12034 (2023)
Breast cancer (BC) is the most common cancer in women, with metastatic BC being responsible for the highest number of deaths. A frequent site for BC metastasis is the brain. Brain metastasis derived from BC involves the cooperation of multiple geneti
Externí odkaz:
https://doaj.org/article/7f0e9555eb244de6b32cfd6e03fed370
Autor:
Ling Liu, Jinghua Feng, Julian Polimeni, Manli Zhang, Hai Nguyen, Urmi Das, Xu Zhang, Harminder Singh, Xiao-Jian Yao, Etienne Leygue, Sam K. P. Kung, Jiuyong Xie
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Circulating cell-free methyl-DNA (mcfDNA) contains promising cancer markers but its low abundance and possibly diverse origin pose challenges toward the accurate diagnosis of early stage cancers. By whole-genome bisulfite sequencing (WGBS) of cell-fr
Externí odkaz:
https://doaj.org/article/ac5887c59c774017bb3044d25d753a45
Autor:
Anne A. Blanchard, Xiuli Ma, Nan Wang, Sabine Hombach-Klonisch, Carla Penner, Arzu Ozturk, Thomas Klonisch, Marshall Pitz, Leigh Murphy, Etienne Leygue, Yvonne Myal
Publikováno v:
Translational Oncology, Vol 12, Iss 3, Pp 561-575 (2019)
Recent studies provide compelling evidence to suggest that the tight junction protein claudin 1, aberrantly expressed in several cancer types, plays an important role in cancer progression. Dysregulation of claudin 1 has been shown to induce epitheli
Externí odkaz:
https://doaj.org/article/d749761141ef4a0da9a809529ccffee2
Autor:
Lucas E. L. Terceiro, Chidalu A. Edechi, Nnamdi M. Ikeogu, Barbara E. Nickel, Sabine Hombach-Klonisch, Tanveer Sharif, Etienne Leygue, Yvonne Myal
Publikováno v:
Cancers, Vol 13, Iss 19, p 4798 (2021)
The tumor microenvironment plays a pivotal role in the tumorigenesis, progression, and metastatic spread of many cancers including breast. There is now increasing evidence to support the observations that a bidirectional interplay between breast canc
Externí odkaz:
https://doaj.org/article/9c7f3b4ab9074d3f961cc56ca7db917e
Publikováno v:
Journal of Clinical Medicine, Vol 4, Iss 12, Pp 1960-1976 (2015)
Claudin 1 is a small transmembrane protein responsible for maintaining the barrier function that exists between epithelial cells. A tight junction protein that regulates the paracellular transport of small ions across adjacent cells, claudin 1 mainta
Externí odkaz:
https://doaj.org/article/88ee1dde9030413c848d8c811abbf655
Autor:
Anne A Blanchard, Teresa Zelinski, Jiuyong Xie, Steven Cooper, Carla Penner, Etienne Leygue, Yvonne Myal
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0163387 (2016)
BACKGROUND:The claudin 1 tight junction protein, solely responsible for the barrier function of epithelial cells, is frequently down regulated in invasive human breast cancer. The underlying mechanism is largely unknown, and no obvious mutations in t
Externí odkaz:
https://doaj.org/article/c7a94404039f46d69278a0df073da928
Autor:
Lucas E. L. Terceiro, Chidalu A Edechi, Anne Blanchard, Yvonne Myal, Barbara Triggs-Raine, Etienne Leygue, Agnes Fresnoza
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 100:86-91
Prolactin-inducible protein (PIP) is a multifunctional glycoprotein that is highly expressed and found in the secretions of apocrine glands such as salivary, lacrimal, and sweat glands including the mammary glands. PIP has been implicated in various
Autor:
Lucas E. L. Terceiro, Maryam Amini, Etienne Leygue, Barbara E. Nickel, Mohammad K. Hamedani, Yvonne Myal, Chidalu A Edechi
Publikováno v:
J Histochem Cytochem
The tight junction membrane protein claudin 1 and the adherens junction protein E-cadherin play critical roles in cell–cell communication and in cell signaling. As a result, their protein levels and distribution in cancer have been a focus of cance
Autor:
Yvonne Myal, Marshall Pitz, Sabine Hombach-Klonisch, Etienne Leygue, Nan Wang, Xiuli Ma, Anne Blanchard, Arzu Öztürk, Leigh C. Murphy, Carla Penner, Thomas Klonisch
Publikováno v:
Translational Oncology, Vol 12, Iss 3, Pp 561-575 (2019)
Recent studies provide compelling evidence to suggest that the tight junction protein claudin 1, aberrantly expressed in several cancer types, plays an important role in cancer progression. Dysregulation of claudin 1 has been shown to induce epitheli
Autor:
Tanveer Sharif, Sabine Hombach-Klonisch, Nnamdi M Ikeogu, Yvonne Myal, Lucas E. L. Terceiro, Barbara E. Nickel, Chidalu A Edechi, Etienne Leygue
Publikováno v:
Cancers
Cancers, Vol 13, Iss 4798, p 4798 (2021)
Cancers, Vol 13, Iss 4798, p 4798 (2021)
Simple Summary The spread of breast cancer to distant parts of the body (metastasis) is the major cause of death in breast cancer patients. Research has shown that apart from the breast cancer cells themselves, other cells and molecules in the vicini