Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Etienne Leygue"'
Autor:
Anne A. Blanchard, Xiuli Ma, Nan Wang, Sabine Hombach-Klonisch, Carla Penner, Arzu Ozturk, Thomas Klonisch, Marshall Pitz, Leigh Murphy, Etienne Leygue, Yvonne Myal
Publikováno v:
Translational Oncology, Vol 12, Iss 3, Pp 561-575 (2019)
Recent studies provide compelling evidence to suggest that the tight junction protein claudin 1, aberrantly expressed in several cancer types, plays an important role in cancer progression. Dysregulation of claudin 1 has been shown to induce epitheli
Externí odkaz:
https://doaj.org/article/d749761141ef4a0da9a809529ccffee2
Autor:
Ling Liu, Jinghua Feng, Julian Polimeni, Manli Zhang, Hai Nguyen, Urmi Das, Xu Zhang, Harminder Singh, Xiao-Jian Yao, Etienne Leygue, Sam K. P. Kung, Jiuyong Xie
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Circulating cell-free methyl-DNA (mcfDNA) contains promising cancer markers but its low abundance and possibly diverse origin pose challenges toward the accurate diagnosis of early stage cancers. By whole-genome bisulfite sequencing (WGBS) of cell-fr
Externí odkaz:
https://doaj.org/article/ac5887c59c774017bb3044d25d753a45
Autor:
Anne A Blanchard, Teresa Zelinski, Jiuyong Xie, Steven Cooper, Carla Penner, Etienne Leygue, Yvonne Myal
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0163387 (2016)
BACKGROUND:The claudin 1 tight junction protein, solely responsible for the barrier function of epithelial cells, is frequently down regulated in invasive human breast cancer. The underlying mechanism is largely unknown, and no obvious mutations in t
Externí odkaz:
https://doaj.org/article/c7a94404039f46d69278a0df073da928
Autor:
Lucas E. L. Terceiro, Chidalu A Edechi, Anne Blanchard, Yvonne Myal, Barbara Triggs-Raine, Etienne Leygue, Agnes Fresnoza
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 100:86-91
Prolactin-inducible protein (PIP) is a multifunctional glycoprotein that is highly expressed and found in the secretions of apocrine glands such as salivary, lacrimal, and sweat glands including the mammary glands. PIP has been implicated in various
Autor:
Lucas E. L. Terceiro, Maryam Amini, Etienne Leygue, Barbara E. Nickel, Mohammad K. Hamedani, Yvonne Myal, Chidalu A Edechi
Publikováno v:
J Histochem Cytochem
The tight junction membrane protein claudin 1 and the adherens junction protein E-cadherin play critical roles in cell–cell communication and in cell signaling. As a result, their protein levels and distribution in cancer have been a focus of cance
Autor:
Yvonne Myal, Marshall Pitz, Sabine Hombach-Klonisch, Etienne Leygue, Nan Wang, Xiuli Ma, Anne Blanchard, Arzu Öztürk, Leigh C. Murphy, Carla Penner, Thomas Klonisch
Publikováno v:
Translational Oncology, Vol 12, Iss 3, Pp 561-575 (2019)
Recent studies provide compelling evidence to suggest that the tight junction protein claudin 1, aberrantly expressed in several cancer types, plays an important role in cancer progression. Dysregulation of claudin 1 has been shown to induce epitheli
Autor:
Tanveer Sharif, Sabine Hombach-Klonisch, Nnamdi M Ikeogu, Yvonne Myal, Lucas E. L. Terceiro, Barbara E. Nickel, Chidalu A Edechi, Etienne Leygue
Publikováno v:
Cancers
Cancers, Vol 13, Iss 4798, p 4798 (2021)
Cancers, Vol 13, Iss 4798, p 4798 (2021)
Simple Summary The spread of breast cancer to distant parts of the body (metastasis) is the major cause of death in breast cancer patients. Research has shown that apart from the breast cancer cells themselves, other cells and molecules in the vicini
Autor:
Mohammad K. Hamedani, Ihsan Turan, Ali Kemal Topaloglu, Eda Mengen, Gamze Akkus, Leman Damla Kotan, Etienne Leygue, Yi Yan, Fatih Gurbuz, Ian M. Carr, Bilgin Yüksel, Şükran Darcan, Samim Özen, Ayca Ulubay, Charlton Cooper
Publikováno v:
Journal of Clinical Research in Pediatric Endocrinology
WOS: 000378169400002
PubMed ID: 27086651
Objective: What initiates the pubertal process in humans and other mammals is still unknown. We hypothesized that gene(s) taking roles in triggering human puberty may be identified by studying a coho
PubMed ID: 27086651
Objective: What initiates the pubertal process in humans and other mammals is still unknown. We hypothesized that gene(s) taking roles in triggering human puberty may be identified by studying a coho
Autor:
Nikesh Tailor, Etienne Leygue, Carolina Gonzalez, Mohammad K. Hamedani, James R. Davie, Dilshad H. Khan
Publikováno v:
Journal of Cellular Physiology. 231:2196-2204
Pre-mRNA splicing is a cotranscriptional process affected by the chromatin architecture along the body of coding genes. Recruited to the pre-mRNA by splicing factors, histone deacetylases (HDACs) and K-acetyltransferases (KATs) catalyze dynamic histo
Autor:
Yi Yan, Etienne Leygue, Mohammad K. Hamedani, Wayne Xu, James R. Davie, Deborah Tsuyuki, Charlton Cooper
Publikováno v:
Cancer Research. 73:P5-11
The steroid receptor RNA activator gene (SRA1) is a particularly intriguing genetic system in that both the corresponding RNA (SRA) and protein (SRAP) have been proven to be functional. Accumulated evidence overall suggests that both molecules act as