Zobrazeno 1 - 10
of 101
pro vyhledávání: '"Etienne Leygue"'
Autor:
Anne A. Blanchard, Xiuli Ma, Nan Wang, Sabine Hombach-Klonisch, Carla Penner, Arzu Ozturk, Thomas Klonisch, Marshall Pitz, Leigh Murphy, Etienne Leygue, Yvonne Myal
Publikováno v:
Translational Oncology, Vol 12, Iss 3, Pp 561-575 (2019)
Recent studies provide compelling evidence to suggest that the tight junction protein claudin 1, aberrantly expressed in several cancer types, plays an important role in cancer progression. Dysregulation of claudin 1 has been shown to induce epitheli
Externí odkaz:
https://doaj.org/article/d749761141ef4a0da9a809529ccffee2
Autor:
Ling Liu, Jinghua Feng, Julian Polimeni, Manli Zhang, Hai Nguyen, Urmi Das, Xu Zhang, Harminder Singh, Xiao-Jian Yao, Etienne Leygue, Sam K. P. Kung, Jiuyong Xie
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Circulating cell-free methyl-DNA (mcfDNA) contains promising cancer markers but its low abundance and possibly diverse origin pose challenges toward the accurate diagnosis of early stage cancers. By whole-genome bisulfite sequencing (WGBS) of cell-fr
Externí odkaz:
https://doaj.org/article/ac5887c59c774017bb3044d25d753a45
Autor:
Lucas E. L. Terceiro, Chidalu A Edechi, Anne Blanchard, Yvonne Myal, Barbara Triggs-Raine, Etienne Leygue, Agnes Fresnoza
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 100:86-91
Prolactin-inducible protein (PIP) is a multifunctional glycoprotein that is highly expressed and found in the secretions of apocrine glands such as salivary, lacrimal, and sweat glands including the mammary glands. PIP has been implicated in various
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eaaf6876ce58868ad0076dedeca7e09
https://doi.org/10.1139/cjpp-2021-0306
https://doi.org/10.1139/cjpp-2021-0306
Autor:
Lucas E. L. Terceiro, Maryam Amini, Etienne Leygue, Barbara E. Nickel, Mohammad K. Hamedani, Yvonne Myal, Chidalu A Edechi
Publikováno v:
J Histochem Cytochem
The tight junction membrane protein claudin 1 and the adherens junction protein E-cadherin play critical roles in cell–cell communication and in cell signaling. As a result, their protein levels and distribution in cancer have been a focus of cance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75c159a956ce6ee7ded75ea59ddd5eed
https://doi.org/10.1369/00221554211055240
https://doi.org/10.1369/00221554211055240
Autor:
Anne A Blanchard, Teresa Zelinski, Jiuyong Xie, Steven Cooper, Carla Penner, Etienne Leygue, Yvonne Myal
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0163387 (2016)
BACKGROUND:The claudin 1 tight junction protein, solely responsible for the barrier function of epithelial cells, is frequently down regulated in invasive human breast cancer. The underlying mechanism is largely unknown, and no obvious mutations in t
Externí odkaz:
https://doaj.org/article/c7a94404039f46d69278a0df073da928
Autor:
Yvonne Myal, Marshall Pitz, Sabine Hombach-Klonisch, Etienne Leygue, Nan Wang, Xiuli Ma, Anne Blanchard, Arzu Öztürk, Leigh C. Murphy, Carla Penner, Thomas Klonisch
Publikováno v:
Translational Oncology, Vol 12, Iss 3, Pp 561-575 (2019)
Recent studies provide compelling evidence to suggest that the tight junction protein claudin 1, aberrantly expressed in several cancer types, plays an important role in cancer progression. Dysregulation of claudin 1 has been shown to induce epitheli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c8246ee8cf3d1d210796258c14f09c1
https://doi.org/10.1016/j.tranon.2018.12.011
https://doi.org/10.1016/j.tranon.2018.12.011
Autor:
Tanveer Sharif, Sabine Hombach-Klonisch, Nnamdi M Ikeogu, Yvonne Myal, Lucas E. L. Terceiro, Barbara E. Nickel, Chidalu A Edechi, Etienne Leygue
Publikováno v:
Cancers
Cancers, Vol 13, Iss 4798, p 4798 (2021)
Cancers, Vol 13, Iss 4798, p 4798 (2021)
Simple Summary The spread of breast cancer to distant parts of the body (metastasis) is the major cause of death in breast cancer patients. Research has shown that apart from the breast cancer cells themselves, other cells and molecules in the vicini
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbe9f4c865c048412909a23ae87732de
https://doi.org/10.3390/cancers13194798
https://doi.org/10.3390/cancers13194798
Autor:
Nikesh Tailor, Etienne Leygue, Carolina Gonzalez, Mohammad K. Hamedani, James R. Davie, Dilshad H. Khan
Publikováno v:
Journal of Cellular Physiology. 231:2196-2204
Pre-mRNA splicing is a cotranscriptional process affected by the chromatin architecture along the body of coding genes. Recruited to the pre-mRNA by splicing factors, histone deacetylases (HDACs) and K-acetyltransferases (KATs) catalyze dynamic histo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ff519d570912545fa3febcdcf1a7bf0
https://doi.org/10.1002/jcp.25337
https://doi.org/10.1002/jcp.25337
Autor:
Yi Yan, Etienne Leygue, Mohammad K. Hamedani, Wayne Xu, James R. Davie, Deborah Tsuyuki, Charlton Cooper
Publikováno v:
Cancer Research. 73:P5-11
The steroid receptor RNA activator gene (SRA1) is a particularly intriguing genetic system in that both the corresponding RNA (SRA) and protein (SRAP) have been proven to be functional. Accumulated evidence overall suggests that both molecules act as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f28a9b6f8bf7991d427c3170751d529e
https://doi.org/10.1158/0008-5472.sabcs13-p5-11-08
https://doi.org/10.1158/0008-5472.sabcs13-p5-11-08
Autor:
Hou Yu Chen, Etienne Leygue, Dilshad H. Khan, Shannon Healy, Carolina Gonzalez, Charlton Cooper, Jian-Min Sun, Karen T. Smith, James R. Davie, Wayne Xu, Jerry L. Workman
Publikováno v:
Nucleic Acids Research
Histone deacetylases (HDACs) and lysine acetyltransferases (KATs) catalyze dynamic histone acetylation at regulatory and coding regions of transcribed genes. Highly phosphorylated HDAC2 is recruited within corepressor complexes to regulatory regions,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db12836b58eda1e246e2fc8b66796918
https://doi.org/10.1093/nar/gkt1134
https://doi.org/10.1093/nar/gkt1134