Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Etienne Formstecher"'
Autor:
Mark Donovan, Mélanie Salamito, Agnès Thomas-Collignon, Lucie Simonetti, Stephanie Desbouis, Jean-Christophe Rain, Etienne Formstecher, Dominique Bernard
Publikováno v:
PLoS ONE, Vol 15, Iss 5, p e0232679 (2020)
Skin aspartic acid protease (SASPase) is believed to be a key enzyme involved in filaggrin processing during epidermal terminal differentiation. Since little is known about the regulation of SASPase function, the aim of this study was to identify inv
Externí odkaz:
https://doaj.org/article/4f6c3a9128d24d7480873489be931749
Autor:
Florian Bonin, Karim Taouis, Paula Azorin, Ambre Petitalot, Zakia Tariq, Sebastien Nola, Nadège Bouteille, Sandrine Tury, Sophie Vacher, Ivan Bièche, Khadija Ait Rais, Gaelle Pierron, Laetitia Fuhrmann, Anne Vincent-Salomon, Etienne Formstecher, Jacques Camonis, Rosette Lidereau, François Lallemand, Keltouma Driouch
Publikováno v:
BMC Biology, Vol 16, Iss 1, Pp 1-16 (2018)
Abstract Background The WW domain-containing oxidoreductase (WWOX) gene, frequently altered in breast cancer, encodes a tumor suppressor whose function is mediated through its interactions with cancer-related proteins, such as the pro-apoptotic prote
Externí odkaz:
https://doaj.org/article/3bfce873c073485588450a3f1f67b33f
Autor:
Maria P Gavilan, Marina Arjona, Angel Zurbano, Etienne Formstecher, Juan R Martinez-Morales, Michel Bornens, Rosa M Rios
Publikováno v:
PLoS Biology, Vol 13, Iss 3, p e1002087 (2015)
Epithelial morphogenesis involves a dramatic reorganisation of the microtubule cytoskeleton. How this complex process is controlled at the molecular level is still largely unknown. Here, we report that the centrosomal microtubule (MT)-binding protein
Externí odkaz:
https://doaj.org/article/8931271437e747d2be72f57d64e338ad
Autor:
Anika Thyrock, Edith Ossendorf, Martin Stehling, Mark Kail, Tanja Kurtz, Gottfried Pohlentz, Dieter Waschbüsch, Simone Eggert, Etienne Formstecher, Johannes Müthing, Klaus Dreisewerd, Stefan Kins, Bruno Goud, Angelika Barnekow
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e64149 (2013)
Small GTPases of the Rab family are important regulators of a large variety of different cellular functions such as membrane organization and vesicle trafficking. They have been shown to play a role in several human diseases. One prominent member, Ra
Externí odkaz:
https://doaj.org/article/c940de76ac58445eaaa25afd8b77130e
Autor:
Carine Rosse, Etienne Formstecher, Katrina Boeckeler, Yingming Zhao, Joachim Kremerskothen, Michael D White, Jacques H Camonis, Peter J Parker
Publikováno v:
PLoS Biology, Vol 7, Iss 11, p e1000235 (2009)
Atypical protein kinase C (aPKC) isoforms have been implicated in cell polarisation and migration through association with Cdc42 and Par6. In distinct migratory models, the Exocyst complex has been shown to be involved in secretory events and migrati
Externí odkaz:
https://doaj.org/article/95fc10a001594aa89e24f2036822ba77
Autor:
Francois Lallemand, Karim Taouis, Sophie Vacher, Josée Guirouilh-Barbat, Jacques Camonis, Etienne Formstecher, Tatiana Popova, Anne-Sophie Hamy, Ambre Petitalot, Rosette Lidereau, Sandrine Caputo, Sophie Zinn-Justin, Ivan Bieche, Keltouma DRIOUCH
Publikováno v:
Cancer Gene Therapy.
The tumor suppressor gene WWOX is localized in an unstable chromosomal region and its expression is decreased or absent in several types of cancer. A low expression of WWOX is associated with a poor prognosis in breast cancer (BC). It has recently be
Autor:
Laurent Daviet, Rémi Delansorne, Philippe Guedat, Jean-Christophe Rain, Guillaume Boissy, Vincent Collura, Wolfgang Sippl, Catherine Borg-Capra, Alessandra Calabrese, Jacques Camonis, Vasily N. Aushev, Julie Bianchi, Virginie Trouplin, Susan Conrath, Cécile Planquette, Céline Reverdy, Xavier Jacq, Etienne Formstecher, Frédéric Colland
Deregulation of the ubiquitin/proteasome system has been implicated in the pathogenesis of many human diseases, including cancer. Ubiquitin-specific proteases (USP) are cysteine proteases involved in the deubiquitination of protein substrates. Functi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69b7c9eb0a78d607a3ed0a2185eba838
https://doi.org/10.1158/1535-7163.c.6532221.v1
https://doi.org/10.1158/1535-7163.c.6532221.v1
Autor:
Laurent Daviet, Rémi Delansorne, Philippe Guedat, Jean-Christophe Rain, Guillaume Boissy, Vincent Collura, Wolfgang Sippl, Catherine Borg-Capra, Alessandra Calabrese, Jacques Camonis, Vasily N. Aushev, Julie Bianchi, Virginie Trouplin, Susan Conrath, Cécile Planquette, Céline Reverdy, Xavier Jacq, Etienne Formstecher, Frédéric Colland
Supplementary Data from Small-molecule inhibitor of USP7/HAUSP ubiquitin protease stabilizes and activates p53 in cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2e51112a679de8e29abcc1e35e6f3f6
https://doi.org/10.1158/1535-7163.22486059
https://doi.org/10.1158/1535-7163.22486059
Autor:
Rosette Lidereau, François Lallemand, Karim Taouis, Jacques Camonis, Laetitia Fuhrmann, Zakia Tariq, Gaëlle Pierron, Etienne Formstecher, Anne Vincent-Salomon, Ivan Bièche, Khadija Ait Rais, Ambre Petitalot, Paula Azorin, Florian Bonin, Nadège Bouteille, Sebastien Nola, Sophie Vacher, Sandrine Tury, Keltouma Driouch
Publikováno v:
BMC Biology, Vol 16, Iss 1, Pp 1-16 (2018)
BMC Biology
BMC Biology, BioMed Central, 2018, 16 (1), pp.109. ⟨10.1186/s12915-018-0576-6⟩
BMC Biology
BMC Biology, BioMed Central, 2018, 16 (1), pp.109. ⟨10.1186/s12915-018-0576-6⟩
Background The WW domain-containing oxidoreductase (WWOX) gene, frequently altered in breast cancer, encodes a tumor suppressor whose function is mediated through its interactions with cancer-related proteins, such as the pro-apoptotic protein p73α.
Autor:
Michael J. Torres, Clayton R. Hunt, Michael A. White, Rakesh Kumar, Etienne Formstecher, Lawrence G. Lum, Charles Yeaman, Raj K. Pandita, Tej K. Pandita, Yingming Zhao, Nobuo Horikoshi, Aubhishek Zaman, Ozlem Kulak, Kalpana Mujoo
Publikováno v:
Molecular and Cellular Biology. 35:3633-3645
The exocyst is a heterooctomeric complex well appreciated for its role in the dynamic assembly of specialized membrane domains. Accumulating evidence indicates that this macromolecular machine also serves as a physical platform that coordinates regul