Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Etienne Beltzung"'
Autor:
Lisa-Marie Appel, Vedran Franke, Melania Bruno, Irina Grishkovskaya, Aiste Kasiliauskaite, Tanja Kaufmann, Ursula E. Schoeberl, Martin G. Puchinger, Sebastian Kostrhon, Carmen Ebenwaldner, Marek Sebesta, Etienne Beltzung, Karl Mechtler, Gen Lin, Anna Vlasova, Martin Leeb, Rushad Pavri, Alexander Stark, Altuna Akalin, Richard Stefl, Carrie Bernecky, Kristina Djinovic-Carugo, Dea Slade
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-24 (2021)
Here the authors identify PHF3 SPOC domain as a reader of the phosphorylated RNA polymerase II (Pol II) C-terminal domain. They show that PHF3 clusters with Pol II complexes in cells, drives phase separation of Pol II in vitro, and regulates neuronal
Externí odkaz:
https://doaj.org/article/248ef7e0ffd543019b8945fa5bb593d6
Autor:
Gen Lin, Irina Grishkovskaya, Rushad Pavri, Alexander Stark, Anna Vlasova, Richard Štefl, Ursula E. Schoeberl, Melania Bruno, Carrie Bernecky, Lisa-Marie Appel, Vedran Franke, Martin Leeb, Aiste Kasiliauskaite, Carmen Ebenwaldner, Sebastian Kostrhon, Etienne Beltzung, Kristina Djinović-Carugo, Altuna Akalin, Tanja Kaufmann, Dea Slade, Marek Sebesta, Martin Puchinger, Karl Mechtler
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-24 (2021)
Nature Communications
'Nature Communications ', vol: 12, pages: 6078-1-6078-24 (2021)
Nature Communications
'Nature Communications ', vol: 12, pages: 6078-1-6078-24 (2021)
The C-terminal domain (CTD) of the largest subunit of RNA polymerase II (Pol II) is a regulatory hub for transcription and RNA processing. Here, we identify PHD-finger protein 3 (PHF3) as a regulator of transcription and mRNA stability that docks ont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::684420fa3a6b9d0b1c365744254e08a1
https://doi.org/10.1038/s41467-021-26360-2
https://doi.org/10.1038/s41467-021-26360-2
Autor:
Altuna Akalin, Martin Leeb, Irina Grishkovskaya, Gen Lin, Carrie Bernecky, Melania Bruno, Aiste Kasiliauskaite, Vedran Franke, Alexander Stark, Richard Štefl, Martin Puchinger, Karl Mechtler, Lisa-Marie Appel, Ursula E. Schoeberl, Anna Vlasova, Kristina Djinović-Carugo, Sebastian Kostrhon, Etienne Beltzung, Dea Slade, Rushad Pavri
Publikováno v:
SSRN Electronic Journal.
SUMMARYThe C-terminal domain (CTD) of the largest subunit of RNA polymerase II (Pol II) is a regulatory hub for transcription and RNA processing. Here, we identify PHD-finger protein 3 (PHF3) as a new CTD-binding factor that negatively regulates tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8083fa6bf92a25146a4f9e49d7ed067a
https://doi.org/10.2139/ssrn.3543843
https://doi.org/10.2139/ssrn.3543843
Autor:
Susanne Opravil, Melania Bruno, Sebastian Kostrhon, Otto Hudecz, Karl Mechtler, Etienne Beltzung, Tanja Kaufmann, Dea Slade, Graham Warren, Andreas Brachner, Eva Kukolj
Publikováno v:
Journal of Cell Science
Sirtuin 2 (SIRT2) is an NAD-dependent deacetylase known to regulate microtubule dynamics and cell cycle progression. SIRT2 has also been implicated in the pathology of cancer, neurodegenerative diseases and progeria. Here, we show that SIRT2 depletio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2d6cf6868e49a59017358561e113bc8
https://doi.org/10.1242/jcs.192633
https://doi.org/10.1242/jcs.192633