Zobrazeno 1 - 10
of 119
pro vyhledávání: '"Etienne, Coyaud"'
Autor:
Hongxian Zhu, Andrew M. Sydor, Kirsten C. Boddy, Etienne Coyaud, Estelle M. N. Laurent, Aaron Au, Joel M. J. Tan, Bing-Ru Yan, Jason Moffat, Aleixo M. Muise, Christopher M. Yip, Sergio Grinstein, Brian Raught, John H. Brumell
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Salmonella utilizes a type 3 secretion system to translocate virulence proteins (effectors) into host cells during infection1. The effectors modulate host cell machinery to drive uptake of the bacteria into vacuoles, where they can establish
Externí odkaz:
https://doaj.org/article/cb972bdf39654deca965043e86fecd62
Autor:
Yu-Qian Mao, Thiago V. Seraphim, Yimei Wan, Ruikai Wu, Etienne Coyaud, Muhammad Bin Munim, Antonio Mollica, Estelle Laurent, Mohan Babu, Vito Mennella, Brian Raught, Walid A. Houry
Publikováno v:
Cell Reports, Vol 43, Iss 2, Pp 113713- (2024)
Summary: R2TP is a chaperone complex consisting of the AAA+ ATPases RUVBL1 and RUVBL2, as well as RPAP3 and PIH1D1 proteins. R2TP is responsible for the assembly of macromolecular complexes mainly acting through different adaptors. Using proximity-la
Externí odkaz:
https://doaj.org/article/7c22cf9435a24e6dad0a5388e234f529
Autor:
Alice Capuz, Sylvain Osien, Mélodie Anne Karnoub, Soulaimane Aboulouard, Estelle Laurent, Etienne Coyaud, Antonella Raffo-Romero, Marie Duhamel, Amélie Bonnefond, Mehdi Derhourhi, Marco Trerotola, Ikram El Yazidi-Belkoura, David Devos, Monika Zilkova, Firas Kobeissy, Fabien Vanden Abeele, Isabelle Fournier, Dasa Cizkova, Franck Rodet, Michel Salzet
Publikováno v:
Cell Death and Disease, Vol 14, Iss 4, Pp 1-16 (2023)
Abstract Using multi-omics analyses including RNAseq, RT-PCR, RACE-PCR, and shotgun proteomic with enrichment strategies, we demonstrated that newborn rat astrocytes produce neural immunoglobulin constant and variable heavy chains as well as light ch
Externí odkaz:
https://doaj.org/article/4a879d4e7d604bcc8c22d0f2991b82bb
Autor:
Michael Lewis, Berta Terré, Philip A. Knobel, Tao Cheng, Hao Lu, Camille Stephan-Otto Attolini, Jordann Smak, Etienne Coyaud, Isabel Garcia-Cao, Shalu Sharma, Chithran Vineethakumari, Jessica Querol, Gabriel Gil-Gómez, Gabriele Piergiovanni, Vincenzo Costanzo, Sandra Peiró, Brian Raught, Haotian Zhao, Xavier Salvatella, Sudipto Roy, Moe R. Mahjoub, Travis H. Stracker
Publikováno v:
Cell Death and Disease, Vol 14, Iss 3, Pp 1-15 (2023)
Abstract Multiciliated cells (MCCs) project dozens to hundreds of motile cilia from their apical surface to promote the movement of fluids or gametes in the mammalian brain, airway or reproductive organs. Differentiation of MCCs requires the sequenti
Externí odkaz:
https://doaj.org/article/6a20ac16e16e4c6f9816cfefaef6e20f
Autor:
Scott Frendo-Cumbo, Taoyingnan Li, Dustin A. Ammendolia, Etienne Coyaud, Estelle M.N. Laurent, Yuan Liu, Philip J. Bilan, Gordon Polevoy, Brian Raught, Julie A. Brill, Amira Klip, John H. Brumell
Publikováno v:
iScience, Vol 25, Iss 10, Pp 105188- (2022)
Summary: Cell proliferation is dependent on growth factors insulin and IGF1. We sought to identify interactors of IRS1, the most proximal mediator of insulin/IGF1 signaling, that regulate cell proliferation. Using proximity-dependent biotin identific
Externí odkaz:
https://doaj.org/article/ac64290d00ae465c951ce30b06a4ac90
Autor:
Kirsten C. Boddy, Hongxian Zhu, Vanessa M. D’Costa, Caishuang Xu, Ksenia Beyrakhova, Miroslaw Cygler, Sergio Grinstein, Etienne Coyaud, Estelle M. N. Laurent, Jonathan St-Germain, Brian Raught, John H. Brumell
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Salmonella secretes the effector protein SopD into the host cell cytoplasm, leading to scission of the plasma membrane through unclear mechanisms. Here, Boddy et al. show that SopD binds to and inhibits the small GTPase Rab10, thus promoting removal
Externí odkaz:
https://doaj.org/article/c637d11be435406898ecf3fc34ead099
Autor:
Oliver A. Kent, Manipa Saha, Etienne Coyaud, Helen E. Burston, Napoleon Law, Keith Dadson, Sujun Chen, Estelle M. Laurent, Jonathan St-Germain, Ren X. Sun, Yoshinori Matsumoto, Justin Cowen, Aaryn Montgomery-Song, Kevin R. Brown, Charles Ishak, Jose La Rose, Daniel D. De Carvalho, Housheng Hansen He, Brian Raught, Filio Billia, Peter Kannu, Robert Rottapel
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Mutations in RAS-MAPK pathway genes are implicated in Noonan-spectrum, yet up to 20% of cases have unknown cause. Here, the authors identify RREB1 underlying a 6p microdeletion RASopathy-like syndrome and show that RREB1, SIN3A and KDM1A form a trans
Externí odkaz:
https://doaj.org/article/7477dd54517347169cc4551af1667746
Autor:
Nicolas Tarbouriech, Florian Chenavier, Junna Kawasaki, Kamel Bachiri, Jean-Marie Bourhis, Pierre Legrand, Lily L. Freslon, Estelle M. N. Laurent, Elsa Suberbielle, Rob W. H. Ruigrok, Keizo Tomonaga, Daniel Gonzalez-Dunia, Masayuki Horie, Etienne Coyaud, Thibaut Crépin
Publikováno v:
Viruses, Vol 14, Iss 11, p 2358 (2022)
Determining the structural organisation of viral replication complexes and unravelling the impact of infection on cellular homeostasis represent important challenges in virology. This may prove particularly useful when confronted with viruses that po
Externí odkaz:
https://doaj.org/article/34e8c32a029f431cb149b615aea698bd
Autor:
Roxsan Manshouri, Etienne Coyaud, Samrat T. Kundu, David H. Peng, Sabrina A. Stratton, Kendra Alton, Rakhee Bajaj, Jared J. Fradette, Rosalba Minelli, Michael D. Peoples, Alessandro Carugo, Fengju Chen, Christopher Bristow, Jeffrey J. Kovacs, Michelle C. Barton, Tim Heffernan, Chad J. Creighton, Brian Raught, Don L. Gibbons
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Non-small cell lung cancer (NSCLC) is often associated with metastasis to the lungs. Here, the authors perform independent screens and identify NuRD as a co-repressor of ZEB1, and demonstrate TBC1D2b as a downstream target of ZEB1/NuRD complex regula
Externí odkaz:
https://doaj.org/article/175dfc318ac14591a1188315ed141a14
Autor:
Sascha E. Dho, Nancy Silva-Gagliardi, Fabio Morgese, Etienne Coyaud, Emily Lamoureux, Donna M. Berry, Brian Raught, C. Jane McGlade
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-18 (2019)
Abstract MIB1 belongs to the RING domain containing family of E3 ubiquitin ligases. In vertebrates, MIB1 plays an essential role in activation of Notch signaling during development, through the ubiquitination and endocytosis of Notch ligands. More re
Externí odkaz:
https://doaj.org/article/9b094eda6c774a899372bfb15aca2c6c