Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Eti Sinha"'
Autor:
Afaf E. G. Osman, Nuria Mencia-Trinchant, Caner Saygin, Luke Moma, Aelin Kim, Genevieve Housman, Matthew Pozsgai, Eti Sinha, Pooja Chandra, Duane C. Hassane, Andrea Sboner, Kishan Sangani, Nick DiNardi, Christopher Johnson, Sara S. Wallace, Bana Jabri, Hue Luu, Monica L. Guzman, Pinkal Desai, Lucy A. Godley
Publikováno v:
Blood Advances. 7:1910-1914
Clonal hematopoiesis (CH) represents clonal expansion of mutated hematopoietic stem cells detectable in the peripheral blood or bone marrow through next generation sequencing. The current prevailing model posits that CH mutations detected in the peri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f281c791cd646c870defc740c8a105d
https://doi.org/10.1182/bloodadvances.2022008521
https://doi.org/10.1182/bloodadvances.2022008521
Autor:
Dennis Lee, Tyler Augi, Kata Alilovic, Nuria Mencia Trinchant, Eti Sinha, Jorge Contreras, Michael Samuel, Pinkal Desai, Michael Kluk, Brianna N Smith, Gail J. Roboz, Ellen Ritchie, Michael R. Savona, Monica L. Guzman, Justin D. Kaner
Publikováno v:
Blood. 140:3208-3209
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ecbd7d3fe3a11a02268a72abcb5be34
https://doi.org/10.1182/blood-2022-167068
https://doi.org/10.1182/blood-2022-167068
Autor:
Abhay Singh, Nuria Mencia-Trinchant, Elizabeth A. Griffiths, Alaa Altahan, Mahesh Swaminathan, Medhavi Gupta, Matthew Gravina, Rutaba Tajammal, Mark G. Faber, LunBiao Yan, Eti Sinha, Duane C. Hassane, David Neil Hayes, Monica L. Guzman, Renuka Iyer, Eunice S. Wang, Swapna Thota
Publikováno v:
JCO Precis Oncol
PURPOSE Hematologic toxic effects of peptide receptor radionuclide therapy (PRRT) can be permanent. Patients with underlying clonal hematopoiesis (CH) may be more inclined to develop hematologic toxicity after PRRT. However, this association remains
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7ea66f22c10c3ece58e7d0d742ebfe7
https://doi.org/10.1200/po.21.00309
https://doi.org/10.1200/po.21.00309
Autor:
Amanda Przespolewski, Matthew Gravina, Megan M. Herr, Eti Sinha, Nuria Mencia-Trinchant, Elizabeth A. Griffiths, LunBiao Yan, Abhay Singh, Duane C. Hassane, Monica L. Guzman, M. S. Ernstoff, Mahesh Swaminathan, Mark G. Faber, Rutaba Tajammal, Eunice S. Wang, Swapna Thota
Publikováno v:
Blood. 138:4295-4295
Background. DNA methylation is a key epigenetic process involved in development, aging, and cancer. Mutations in DNMT3A and TET2 in the hematopoietic stem cell compartment lead to increased self-renewal. In addition to mutations in ASXL1, collectivel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ed1006cbcbc3155e1f58fb82fb6c81e
https://doi.org/10.1182/blood-2021-150347
https://doi.org/10.1182/blood-2021-150347
Autor:
Eunice S. Wang, Matthew Gravina, Eti Sinha, Swapna Thota, Medhavi Gupta, Monica L. Guzman, Mark G. Faber, Duane C. Hassane, Rutaba Tajammal, Renuka Iyer, Nuria Mencia-Trinchant, LunBiao Yan, Abhay Singh, Elizabeth A. Griffiths
Publikováno v:
Journal of Clinical Oncology. 39:10605-10605
10605 Background: Mutations in TP53 and PPM1D are putative drivers associated with therapy related-myeloid neoplasm (T-MN) and have been identified in pre-treatment blood samples obtained at the time of primary malignancy, predating clinically eviden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21b07fdef42178883e1b127b5c1de6c4
https://doi.org/10.1200/jco.2021.39.15_suppl.10605
https://doi.org/10.1200/jco.2021.39.15_suppl.10605
Publikováno v:
Blood. 134:3721-3721
Clonal hematopoiesis (CH) is described as the phenomenon where hematopoietic cells acquire advantageous somatic mutations that result in a dominant subclonal population. These subclones are linked to various adverse outcomes such as elevated risk of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a503f6ccf58d4a6598396a102c70c96
https://doi.org/10.1182/blood-2019-132222
https://doi.org/10.1182/blood-2019-132222
Autor:
Eti Sinha, Peter Libby, Maia Fefer, Siddhartha Jaiswal, Eugenia Shvartz, Alexander J. Silver, Galina K. Sukhova, Marie McConkey, Philipp J. Rauch, Jk Gopakumar, Benjamin L. Ebert
Publikováno v:
Blood. 132:745-745
Clonal hematopoiesis of indeterminate potential (CHIP) was recently identified as a major risk factor for development of both hematologic malignancies and atherosclerotic cardiovascular disease in humans. The most commonly mutated gene in CHIP, DNMT3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a0e63e52b11ffa7810b4a5cc5b791dd3
https://doi.org/10.1182/blood-2018-99-118288
https://doi.org/10.1182/blood-2018-99-118288