Zobrazeno 1 - 10
of 266
pro vyhledávání: '"Ethel Cesarman"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract Kaposi’s sarcoma (KS) is a cancer affecting skin and internal organs for which the Kaposi’s sarcoma associated herpesvirus (KSHV) is a necessary cause. Previous work has pursued KS diagnosis by quantifying KSHV DNA in skin biopsies using
Externí odkaz:
https://doaj.org/article/4d037401e6d34a3c9e36b9d34ce2ef2a
Publikováno v:
PLoS Pathogens, Vol 20, Iss 4, p e1011939 (2024)
Epstein-Barr virus (EBV) persistently infects 95% of adults worldwide and is associated with multiple human lymphomas that express characteristic EBV latency programs used by the virus to navigate the B-cell compartment. Upon primary infection, the E
Externí odkaz:
https://doaj.org/article/26731686f3c145fda023abbea69b282f
Autor:
Ayana E Morales, Ruby Gumenick, Caitlyn M Genovese, Yun Yeong Jang, Ariene Ouedraogo, Maite Ibáñez de Garayo, Tania Pannellini, Sanjay Patel, Matthew E Bott, Julio Alvarez, Sung Soo Mun, Jennifer Totonchy, Archana Gautam, Jesus Delgado de la Mora, Stephanie Chang, Dagmar Wirth, Marcelo Horenstein, Tao Dao, David A Scheinberg, Paul G Rubinstein, Aggrey Semeere, Jeffrey Martin, Catherine C Godfrey, Carlee B Moser, Roy M Matining, Thomas B Campbell, Margaret Z Borok, Susan E Krown, Ethel Cesarman
Publikováno v:
PLoS Pathogens, Vol 20, Iss 1, p e1011881 (2024)
In people living with HIV, Kaposi Sarcoma (KS), a vascular neoplasm caused by KS herpesvirus (KSHV/HHV-8), remains one of the most common malignancies worldwide. Individuals living with HIV, receiving otherwise effective antiretroviral therapy, may p
Externí odkaz:
https://doaj.org/article/fd71de1d5afd411097ac26c957e4cecc
Autor:
Robert M. Strother, Satish Gopal, Meg Wirth, Amy Chadburn, Ariela Noy, Ethel Cesarman, Jeannette Y. Lee, Scot C. Remick, Naftali Busakhala, Bongani Kaimila, Elson Mberi, Ntokozo Ndlovu, Abrahams Omoding, Susan E. Krown
Publikováno v:
JCO Global Oncology, Vol , Iss 6, Pp 1034-1040 (2020)
The purpose of this article is to describe lessons from the first lymphoma clinical trial conducted by the AIDS Malignancy Consortium (AMC) in sub-Saharan Africa (SSA). AMC-068 was a randomized phase II comparison of intravenous versus oral chemother
Externí odkaz:
https://doaj.org/article/08bb5c67bdcb4a90a8d8243f2195ff45
Autor:
Lilie L. Lin, David S. Lakomy, Elizabeth Y. Chiao, Robert M. Strother, Meg Wirth, Ethel Cesarman, Margaret Borok, Naftali Busakhala, Carla J. Chibwesha, Lameck Chinula, Ntokozo Ndlovu, Jackson Orem, Warren Phipps, Vikash Sewram, Samantha L. Vogt, Joseph A. Sparano, Ronald T. Mitsuyasu, Susan E. Krown, Satish Gopal
Publikováno v:
JCO Global Oncology, Vol , Iss 6, Pp 1134-1146 (2020)
PURPOSEThe aim of this study was to review the current status of clinical trials for HIV-associated malignancies in people living with HIV in sub-Saharan Africa (SSA) and efforts made by the AIDS Malignancy Consortium (AMC) to build capacity in SSA f
Externí odkaz:
https://doaj.org/article/79b9238cbebd496bbde3be934652fcc7
Autor:
Jouliana Sadek, Michael G. Wuo, David Rooklin, Arthur Hauenstein, Seong Ho Hong, Archana Gautam, Hao Wu, Yingkai Zhang, Ethel Cesarman, Paramjit S. Arora
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
NF-κB signalling involves the scaffold protein NEMO, which can be bound by the oncoprotein vFLIP to promote cell survival and oncogenic transformation. Here the authors rationally engineer a tertiary protein mimic of NEMO to disrupt the vFLIP-NEMO i
Externí odkaz:
https://doaj.org/article/c91a73658de949548aa1a6962b0fe8cd
Autor:
Francesco Maura, Bachisio Ziccheddu, Jenny Z. Xiang, Bhavneet Bhinder, Joel Rosiene, Federico Abascal, Kylee H. Maclachlan, Kenneth Wha Eng, Manik Uppal, Feng He, Wei Zhang, Qi Gao, Venkata D. Yellapantula, Vicenta Trujillo-Alonso, Sunita I. Park, Matthew J. Oberley, Elizabeth Ruckdeschel, Megan S. Lim, Gerald B. Wertheim, Matthew J. Barth, Terzah M. Horton, Andriy Derkach, Alexandra E. Kovach, Christopher J. Forlenza, Yanming Zhang, Ola Landgren, Craig H. Moskowitz, Ethel Cesarman, Marcin Imielinski, Olivier Elemento, Mikhail Roshal, Lisa Giulino-Roth
Publikováno v:
Blood Cancer Discovery. 4:208-227
The rarity of malignant Hodgkin and Reed Sternberg (HRS) cells in classic Hodgkin lymphoma (cHL) limits the ability to study the genomics of cHL. To circumvent this, our group has previously optimized fluorescence-activated cell sorting to purify HRS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92db280bf9e148c37153d90fb56ce22e
https://doi.org/10.1158/2643-3230.bcd-22-0128
https://doi.org/10.1158/2643-3230.bcd-22-0128
Autor:
María Victoria Medina, Agata D Agostino, Qi Ma, Pilar Eroles, Lucas Cavallin, Chiara Chiozzini, Daiana Sapochnik, Cora Cymeryng, Elizabeth Hyjek, Ethel Cesarman, Julian Naipauer, Enrique A Mesri, Omar A Coso
Publikováno v:
PLoS Pathogens, Vol 16, Iss 10, p e1009006 (2020)
Kaposi's sarcoma-associated herpesvirus (KSHV) vGPCR is a constitutively active G protein-coupled receptor that subverts proliferative and inflammatory signaling pathways to induce cell transformation in Kaposi's sarcoma. Cyclooxygenase-2 (COX-2) is
Externí odkaz:
https://doaj.org/article/f5e580b584b8453f930179944d01482b
Autor:
Joseph A. Sparano, Jeannette Y. Lee, Lawrence D. Kaplan, Juan Carlos Ramos, Richard F. Ambinder, William Wachsman, David Aboulafia, Ariela Noy, David H. Henry, Lee Ratner, Ethel Cesarman, Amy Chadburn, Ronald Mitsuyasu
Publikováno v:
Haematologica, Vol 106, Iss 3 (2020)
Four cycles of rituximab plus CHOP chemotherapy is as effective as 6 cycles in low-risk diffuse large B-cell lymphoma (DLBCL). Here we report a post-hoc analysis of a prospective clinical trial in patients with HIV-associated DLBCL and high-grade lym
Externí odkaz:
https://doaj.org/article/078d20628e604f39b442cee01904788e
Autor:
Barbara Ruder, Claudia Günther, Michael Stürzl, Markus Friedrich Neurath, Ethel Cesarman, Gianna Ballon, Christoph Becker
Publikováno v:
PLoS ONE, Vol 15, Iss 1, p e0228441 (2020)
A strict cell death control in the intestinal epithelium is indispensable to maintain barrier integrity and homeostasis. In order to achieve a balance between cell proliferation and cell death, a tight regulation of Caspase-8, which is a key player i
Externí odkaz:
https://doaj.org/article/0b4ba5ed71d143da9331b10e3d6837a9