Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Ethan R, Block"'
Autor:
Kristen Bucchin, Michael J. Calderon, Judith Joyce Balcita-Pedicino, Alexander Sorkin, Tarique Rajasaheb Bagalkot, Susan R. Sesack, Ethan R. Block
Publikováno v:
J Neurosci
Dopamine transporter (DAT) controls dopamine neurotransmission by clearing synaptically released dopamine. However, trafficking itineraries of DAT, which determine its cell-surface concentration near synapses, are poorly characterized. It is especial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d29d2fafbda883afdccbf0fc01b974c
https://doi.org/10.1523/jneurosci.0744-20.2020
https://doi.org/10.1523/jneurosci.0744-20.2020
Autor:
Cihan Kaya, Ethan R. Block, James R. Faeder, Mary Hongying Cheng, Terrence J. Sejnowski, Alexander Sorkin, Thomas M. Bartol, Ivet Bahar
Publikováno v:
eNeuro
Efficient clearance of dopamine (DA) from the synapse is key to regulating dopaminergic signaling. This role is fulfilled by DA transporters (DATs). Recent advances in the structural characterization of DAT fromDrosophila(dDAT) and in high-resolution
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bdd47efe471e3ab751b61d34d190fb2
http://europepmc.org/articles/PMC5804147
http://europepmc.org/articles/PMC5804147
Autor:
Alexander Sorkin, Susan R. Sesack, Jacob Nuttle, Judith Joyce Balcita-Pedicino, Simon C. Watkins, Ethan R. Block, John Caltagarone
Publikováno v:
The Journal of Neuroscience. 35:12845-12858
The dopamine (DA) transporter (DAT) controls dopaminergic neurotransmission by removing extracellular DA. Although DA reuptake is proposed to be regulated by DAT traffic to and from the cell surface, the membrane trafficking system involved in the en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7f3026ec3e10b9e15d1b09fb6e52ab1
https://doi.org/10.1523/jneurosci.1391-15.2015
https://doi.org/10.1523/jneurosci.1391-15.2015
Publikováno v:
Bioconjugate Chemistry
Monoclonal antibodies are one of the most useful and ubiquitous affinity reagents used in the biological sciences. Immunostaining of fixed and live cells for microscopy or cytometry measurements frequently employs fluorescently labeled antibodies, in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::129937d391c77cd9780a16c51bab1481
https://doi.org/10.1021/bc500273n
https://doi.org/10.1021/bc500273n
Publikováno v:
Cellular Signalling. 23:2051-2055
Wounding usually causes considerable cell damage, and released ATP promotes migration of nearby epithelium. ATP binds to purinergic receptors on the cell surface and induces transactivation of the EGF receptor through signaling by the Src family kina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d1a60e2a5382a17163eb860b2b2d4c3
https://doi.org/10.1016/j.cellsig.2011.07.021
https://doi.org/10.1016/j.cellsig.2011.07.021
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1810:875-878
Heparin-binding EGF-like growth factor (HB-EGF) contains, in contrast to EGF, a domain that binds to negatively charged glycans on cell surfaces and in extracellular matrix. We speculated that a short exposure to HB-EGF induces prolonged biological e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6743ea633b882070012f5e36dad9eeb1
https://doi.org/10.1016/j.bbagen.2011.05.011
https://doi.org/10.1016/j.bbagen.2011.05.011
Autor:
Ethan R. Block, Kira L. Lathrop, Rebecca S. Sullenberger, Michael A. Tolino, Jes K. Klarlund, Abigail R. Mazie, Jennifer S. Lozano
Publikováno v:
Molecular Biology of the Cell
Epithelia tend to migrate when edges are present, for instance, after wounding or during development. Using a new tissue culture model, we found that the existence of free edges is in itself a signal that causes activation of the epidermal growth fac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0025a7b009d8de5f2a76a1fb5e7e5fd4
https://doi.org/10.1091/mbc.e09-12-1026
https://doi.org/10.1091/mbc.e09-12-1026
Autor:
Ethan R. Block, Jes K. Klarlund
Publikováno v:
Molecular Biology of the Cell. 19:4909-4917
Wounding epithelia induces activation of the epidermal growth factor receptor (EGFR), which is absolutely required for induction of motility. ATP is released from cells after wounding; it binds to purinergic receptors on the cell surface, and the EGF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8b496cbde6fde25f832d003282e679e
https://doi.org/10.1091/mbc.e08-01-0097
https://doi.org/10.1091/mbc.e08-01-0097
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 112(32)
Based on lysotracker red imaging in cultured hippocampal neurons, antipsychotic drugs (APDs) were proposed to accumulate in synaptic vesicles by acidic trapping and to be released in response to action potentials. Because many APDs are dopamine (DA)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f29d6864eeda12031bbdcfddc3be6b66
https://pubmed.ncbi.nlm.nih.gov/26216995
https://pubmed.ncbi.nlm.nih.gov/26216995
Publikováno v:
Journal of Cell Science. 119:1645-1654
Phospholipase D catalyzes the hydrolysis of phosphatidylcholine to generate phosphatidic acid, and there is currently much interest in elucidating messenger functions for this molecule. We report here that wounding sheets of corneal epithelial and Ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0f9077fe6ff27919d0f9b424a76225a
https://doi.org/10.1242/jcs.02858
https://doi.org/10.1242/jcs.02858