Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Ethan Knight"'
Autor:
Meena Sethuraman, Nagadhara Dronadula, Lianxiang Bi, Bradley K. Wacker, Ethan Knight, Pieter De Bleser, David A. Dichek
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Transduction of endothelial cells (EC) with a vector that expresses apolipoprotein A-I (APOAI) reduces atherosclerosis in arteries of fat-fed rabbits. However, the effects on atherosclerosis are partial and might be enhanced if APOAI express
Externí odkaz:
https://doaj.org/article/2ad6ece108b24aa594c3f46484bd534d
Publikováno v:
AIAA Journal. 58:5095-5106
The phenomenon of onset time after ignition in atmospheric and backpressurized rotating detonation combustors is dealt with in the current Paper. By altering the airflow and fuel flow rates, plenum...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5dcdba90bb34b1abaaf498beb02bf6fe
https://doi.org/10.2514/1.j058263
https://doi.org/10.2514/1.j058263
Autor:
Lianxiang Bi, Bradley K. Wacker, Ethan Knight, Chongren Tang, Lucia Vojtech, Alexis Stamatikos, David A. Dichek
Publikováno v:
Hum Gene Ther
Atherosclerosis is a disease of large- and medium-sized arteries that is caused by cholesterol accumulation in arterial intimal cells, including macrophages and smooth muscle cells (SMC). Cholesterol accumulation in these cells can be prevented or re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::241e90de6bc7a16170694d374b35d8cc
https://doi.org/10.1089/hum.2019.245
https://doi.org/10.1089/hum.2019.245
Autor:
Chongren Tang, Lianxiang Bi, Ethan Knight, Alexis Stamatikos, David A. Dichek, Bradley K. Wacker, Lucia Vojtech
Publikováno v:
Circulation Research. 125
Background: The microRNA miR-33a-5p impairs apoAI-mediated cholesterol efflux by silencing ABCA1 expression. Systemic injection of antagomirs to miR-33a-5p reduces atherosclerosis but can cause hepatic steatosis and hypertriglyceridemia. In contrast,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f3d9e50854afd9be8f1b915d050fdd97
https://doi.org/10.1161/res.125.suppl_1.884
https://doi.org/10.1161/res.125.suppl_1.884
Autor:
Chongren Tang, Alexis Stamatikos, Francis Kim, Bradley K. Wacker, Philip Ng, Nagadhara Dronadula, Ethan Knight, Donna Palmer, David A. Dichek
Atherosclerosis, a disease of blood vessels, is driven by cholesterol accumulation and inflammation. Gene therapy that removes cholesterol from blood vessels and decreases inflammation is a promising approach for prevention and treatment of atheroscl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69fafd787069bcc0b4cd18788cd94e2d
https://europepmc.org/articles/PMC6383573/
https://europepmc.org/articles/PMC6383573/
Publikováno v:
2018 Joint Propulsion Conference.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb1d604ae861d3db2b21c13b10ceea98
https://doi.org/10.2514/6.2018-4575.c1
https://doi.org/10.2514/6.2018-4575.c1
Publikováno v:
2018 Joint Propulsion Conference.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b3406ae66db499e7626b177a5cc9082
https://doi.org/10.2514/6.2018-4568
https://doi.org/10.2514/6.2018-4568
Publikováno v:
2018 Joint Propulsion Conference.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::518e658ab5112d4bb901cc387fa23d91
https://doi.org/10.2514/6.2018-4575
https://doi.org/10.2514/6.2018-4575
Autor:
Chongren Tang, Bradley K. Wacker, Philip Ng, Ethan Knight, Alexis Stamatikos, David A. Dichek, Nagadhara Dronadula, Donna Palmer, Francis Kim
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 38
Background: ABCA1 removes cholesterol from vascular wall cells via apoAI-mediated efflux, generating HDL that transports cholesterol to the liver for excretion. This process of reverse cholesterol transport is atheroprotective; therefore, strategies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66d1fe533080c0d77452732a59763c6a
https://doi.org/10.1161/atvb.38.suppl_1.628
https://doi.org/10.1161/atvb.38.suppl_1.628
Publikováno v:
Aerospace Science and Technology. 93:105350
A circular array of six pulse detonation combustors is integrated to an axial turbine, to extract power from the detonative combustion process that is ignited cyclically in the array of tubes. The effect of pulsing frequency, fill fraction and rotor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1cff5cd411df8abf6430bd30f4e277e4
https://doi.org/10.1016/j.ast.2019.105350
https://doi.org/10.1016/j.ast.2019.105350