Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Ethan Jain‐Washburn"'
Autor:
Alexander M. Kulminski, Ethan Jain‐Washburn, Ian Philipp, Yury Loika, Elena Loiko, Irina Culminskaya
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 16, Iss 2, Pp n/a-n/a (2024)
Abstract INTRODUCTION The variability in apolipoprotein E (APOE) ε4‐attributed susceptibility to Alzheimer's disease (AD) across ancestries, sexes, and ages may stem from the modulating effects of other genetic variants. METHODS We examined associ
Externí odkaz:
https://doaj.org/article/f942fc4def444aaf801aad1a51aec5af
Autor:
Alexander M. Kulminski, Ethan Jain‐Washburn, Ian Philipp, Liang He, Yury Loika, Elena Loiko, Olivia Bagley, Svetlana Ukraintseva, Anatoliy Yashin, Konstantin Arbeev, Eric Stallard, Mary F. Feitosa, Nicole Schupf, Kaare Christensen, Irina Culminskaya
Publikováno v:
Aging Cell. 21
Age-related diseases characteristic of post-reproductive life, aging, and life span are the examples of polygenic non-Mendelian traits with intricate genetic architectures. Polygenicity of these traits implies that multiple variants can impact their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c0ff7575b94bde4803356c88af5bd2b
https://doi.org/10.1111/acel.13730
https://doi.org/10.1111/acel.13730
Autor:
Alexander M, Kulminski, Ethan, Jain-Washburn, Elena, Loiko, Yury, Loika, Fan, Feng, Irina, Culminskaya
Publikováno v:
Aging. 14
Capturing the genetic architecture of Alzheimer's disease (AD) is challenging because of the complex interplay of genetic and non-genetic factors in its etiology. It has been suggested that AD biomarkers may improve the characterization of AD patholo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ce7efcea82e007e4425aadc8c7c19ce9
https://pubmed.ncbi.nlm.nih.gov/36399096
https://pubmed.ncbi.nlm.nih.gov/36399096
Autor:
Alexander Kulminski, Ethan Jain-Washburn, Ian Philipp, Konstantin Arbeev, Eric Stallard, Mary Feitosa, Nicole Schupf, Kaare Christensen
Publikováno v:
Innovation in Aging. 6:442-442
Multifactorial diseases, health-related traits, and lifespan are polygenic phenotypes with complex genetic architectures. Polygenicity implies that multiple variants can impact the risks of these phenotypes independently or jointly. Recently, we show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a753695c50c8f70e40baf2225ac71f9
https://doi.org/10.1093/geroni/igac059.1732
https://doi.org/10.1093/geroni/igac059.1732