Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Ethan Fitzgerald"'
Autor:
Evan Y. Snyder, Angela R. Ozburn, Colleen A. McClung, Mariah A. Hildebrand, George C. Tseng, Jeffrey Oliver-Smith, Matthew B Jarpe, Alicia M. Winquist, Hui Zhang, Wei Zong, Puja K. Parekh, Darius Becker-Krail, Zhiguang Huo, Ethan Fitzgerald, Rachel N. Arey, Xiyu Zhu, Lauren M. DePoy, Andrew Crain, Kyle D. Ketchesin, Brian T. D. Tobe, Xiangning Xue, Ryan W. Logan
Publikováno v:
Molecular psychiatry
Valproate (VPA) has been used in the treatment of bipolar disorder since the 1990s. However, the therapeutic targets of VPA have remained elusive. Here we employ a preclinical model to identify the therapeutic targets of VPA. We find compounds that i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de3c998801c8fc52a7971dd952089690
http://europepmc.org/articles/PMC8141541
http://europepmc.org/articles/PMC8141541
Autor:
Yanhua H. Huang, Jun Yoshino, Poornima Sundarvelu, Puja K. Parekh, Darius Becker-Krail, Colleen A. McClung, Spencer Waplinger, Ethan Fitzgerald, Wilbur P. Williams, Ryan W. Logan, Xiyu Zhu, Micah A. Shelton, John F. Enwright, Hui Zhang, Gabrielle N. Kaplan, Jeffrey Oliver-Smith, Shintaro Yamaguchi
Publikováno v:
Molecular psychiatry
The diurnal regulation of dopamine is important for normal physiology and diseases such as addiction. Here we find a novel role for the CLOCK protein to antagonize CREB-mediated transcriptional activity at the tyrosine hydroxylase (TH) promoter, whic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7a48f750cdd1235f64986339e34e131
https://doi.org/10.1038/s41380-018-0061-1
https://doi.org/10.1038/s41380-018-0061-1
Publikováno v:
OBM Geriatrics. :1-1
Alzheimer’s Disease (AD) is the leading cause of dementia worldwide, and represents a significant cause of cognitive decline, disability, and mortality. Ongoing clinical trials continue to investigate β-amyloid targeted therapy with unclear benefi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09dd6e92644dad9b0d1f9c2d2d075c40
https://doi.org/10.21926/obm.geriatr.2102170
https://doi.org/10.21926/obm.geriatr.2102170
Autor:
Colleen A. McClung, Ethan Fitzgerald, Rachel N. Arey, Xiyu Zhu, Ryan W. Logan, Angela R. Ozburn
Publikováno v:
Biological Psychiatry. 83:S66
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d980646e0c76724a92e42d4368651544
https://doi.org/10.1016/j.biopsych.2018.02.181
https://doi.org/10.1016/j.biopsych.2018.02.181