Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Ethan C. Garner"'
Publikováno v:
mBio, Vol 14, Iss 5 (2023)
ABSTRACT Most bacteria are surrounded by their cell wall, containing a highly cross-linked protective envelope of peptidoglycan. To grow, bacteria must continuously remodel their wall, inserting new material and breaking old bonds. Bond cleavage is p
Externí odkaz:
https://doaj.org/article/7747bee986eb4da8b724635fc1c367ee
Autor:
Devon A. Stork, Georgia R. Squyres, Erkin Kuru, Katarzyna A. Gromek, Jonathan Rittichier, Aditya Jog, Briana M. Burton, George M. Church, Ethan C. Garner, Aditya M. Kunjapur
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
B. subtilis is valuable both as a model for cell biology and as an industrial organism. Here the authors use genetic code expansion to enable functional tools for exploring cell division dynamics.
Externí odkaz:
https://doaj.org/article/7fbe036ed167476082e407a0dae04dd4
Autor:
Joshua W. McCausland, Xinxing Yang, Georgia R. Squyres, Zhixin Lyu, Kevin E. Bruce, Melissa M. Lamanna, Bill Söderström, Ethan C. Garner, Malcolm E. Winkler, Jie Xiao, Jian Liu
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Bacterial protein FtsZ polymerizes at mid-cell and exhibits treadmilling dynamics, driving the movement of enzymes that synthesize septal peptidoglycan. Here, McCausland et al. combine theoretical modelling with single-molecule imaging of bacteria to
Externí odkaz:
https://doaj.org/article/a23599fc4d5a4c45aa6e7629aef838ab
Autor:
Felix Wong, Sean Wilson, Ralf Helbig, Smitha Hegde, Olha Aftenieva, Hai Zheng, Chenli Liu, Teuta Pilizota, Ethan C. Garner, Ariel Amir, Lars D. Renner
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Mechanical rupture, or lysis, of the cytoplasmic membrane is a common cell death pathway in bacteria occurring in response to β-lactam antibiotics. A better understanding of the cellular design principles governing the susceptibility and response of
Externí odkaz:
https://doaj.org/article/17832b622a5c4604841350be642fec93
Autor:
Cynthia L. Darnell, Jenny Zheng, Sean Wilson, Ryan M. Bertoli, Alexandre W. Bisson-Filho, Ethan C. Garner, Amy K. Schmid
Publikováno v:
mBio, Vol 11, Iss 4 (2020)
ABSTRACT Precise control of the cell cycle is central to the physiology of all cells. In prior work we demonstrated that archaeal cells maintain a constant size; however, the regulatory mechanisms underlying the cell cycle remain unexplored in this d
Externí odkaz:
https://doaj.org/article/efe91ec2cd5b4204ab3646133fe6130f
Autor:
Charles L. Dulberger, Carlos A. Guerrero-Bustamante, Siân V. Owen, Sean Wilson, Michael G. Wuo, Rebecca A. Garlena, Lexi A. Serpa, Daniel A. Russell, Junhao Zhu, Ben J. Braunecker, Georgia R. Squyres, Michael Baym, Laura L. Kiessling, Ethan C. Garner, Eric J. Rubin, Graham F. Hatfull
Publikováno v:
Nature Microbiology. 8:695-710
Mycobacteriophages are a diverse group of viruses infecting Mycobacterium with substantial therapeutic potential. However, as this potential becomes realized, the molecular details of phage infection and mechanisms of resistance remain ill-defined. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c97cdc014b38bd235dc5cc85acd13f57
https://doi.org/10.1038/s41564-023-01333-x
https://doi.org/10.1038/s41564-023-01333-x
Autor:
Qingyun Liu, Junhao Zhu, Charles L. Dulberger, Sydney Stanley, Sean Wilson, Eun Seon Chung, Xin Wang, Peter Culviner, Yue J. Liu, Nathan D. Hicks, Gregory H. Babunovic, Samantha R. Giffen, Bree B. Aldridge, Ethan C. Garner, Eric J. Rubin, Michael C. Chao, Sarah M. Fortune
Publikováno v:
Science
The widespread use of antibiotics has placed bacterial pathogens under intense pressure to evolve new survival mechanisms. Genomic analysis of 51,229 Mycobacterium tuberculosis ( Mtb ) clinical isolates has identified an essential transcriptional reg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d37880064609bcfc7844c5dacb52098
https://doi.org/10.1126/science.abq2787
https://doi.org/10.1126/science.abq2787
Publikováno v:
eLife, Vol 8 (2019)
MreB is an actin homolog that is essential for coordinating the cell wall synthesis required for the rod shape of many bacteria. Previously we have shown that filaments of MreB bind to the curved membranes of bacteria and translocate in directions de
Externí odkaz:
https://doaj.org/article/6254eab6aad74167ae27e439032e3bd6
Autor:
Saman Hussain, Carl N Wivagg, Piotr Szwedziak, Felix Wong, Kaitlin Schaefer, Thierry Izoré, Lars D Renner, Matthew J Holmes, Yingjie Sun, Alexandre W Bisson-Filho, Suzanne Walker, Ariel Amir, Jan Löwe, Ethan C Garner
Publikováno v:
eLife, Vol 7 (2018)
MreB is essential for rod shape in many bacteria. Membrane-associated MreB filaments move around the rod circumference, helping to insert cell wall in the radial direction to reinforce rod shape. To understand how oriented MreB motion arises, we alte
Externí odkaz:
https://doaj.org/article/416725f762834c18a4e88f2e574f2fa6
Autor:
Ethan C. Garner
Publikováno v:
Annual Review of Cell and Developmental Biology. 37:1-21
One of the most common bacterial shapes is a rod, yet we have a limited understanding of how this simple shape is constructed. While only six proteins are required for rod shape, we are just beginning to understand how they self-organize to build the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83eb071dcb8cf5be13c1d05176d305aa
https://doi.org/10.1146/annurev-cellbio-010521-010834
https://doi.org/10.1146/annurev-cellbio-010521-010834