Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Ethan C Settembre"'
Autor:
Michael Cheung, Cheng Chang, Raveen Rathnasinghe, Evan Rossignol, Yunfei Zhang, Annette Ferrari, Harsh Patel, Yanjun Huang, Michelle Sanchez Guillen, Tina Scalzo, Changkeun Lee, Gillis R. Otten, Ethan C. Settembre, Nedzad Music, Giuseppe Palladino, Yingxia Wen
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-12 (2023)
Abstract Currently licensed influenza vaccines focus immune responses on viral hemagglutinin (HA), while the other major surface glycoprotein neuraminidase (NA) is not tightly controlled in inactivated vaccine formulations despite evidence that anti-
Externí odkaz:
https://doaj.org/article/34eefbdcbdca47e4b9effcc04a79f050
Autor:
Cheng Chang, Nedzad Music, Michael Cheung, Evan Rossignol, Sukhmani Bedi, Harsh Patel, Mohammad Safari, Changkeun Lee, Gillis R. Otten, Ethan C. Settembre, Giuseppe Palladino, Yingxia Wen
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 27, Iss , Pp 195-205 (2022)
Vaccines are the primary intervention against influenza. Currently licensed inactivated vaccines focus immunity on viral hemagglutinin (HA). Self-amplifying mRNA (sa-mRNA) vaccines offer an opportunity to generate immunity to multiple viral proteins,
Externí odkaz:
https://doaj.org/article/912ad34f33834057b76e58f148316bfd
Autor:
Giuseppe Palladino, Cheng Chang, Changkeun Lee, Nedzad Music, Ivna De Souza, Jonathan Nolasco, Samuel Amoah, Pirada Suphaphiphat, Gillis R. Otten, Ethan C. Settembre, Yingxia Wen
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 25, Iss , Pp 225-235 (2022)
The spike (S) protein of SARS-CoV-2 plays a crucial role in cell entry, and the nucleocapsid (N) protein is highly conserved among human coronavirus homologs. For potentially broad effectiveness against both original virus and emerging variants, we d
Externí odkaz:
https://doaj.org/article/f78df334f83d4554ba745ba254900e27
Autor:
Cheng Chang, Nedzad Music, Michael Cheung, Evan Rossignol, Sukhmani Bedi, Harsh Patel, Mohammad Safari, Changkeun Lee, Gillis R. Otten, Ethan C. Settembre, Giuseppe Palladino, Yingxia Wen
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 28, Iss , Pp 11- (2023)
Externí odkaz:
https://doaj.org/article/f42ddb960d474101a8756cdd0d6e57e5
Autor:
Rhiannon R. Penkert, Sumana Chandramouli, Philip R. Dormitzer, Ethan C. Settembre, Robert E. Sealy, Susan Wong, Neal S. Young, Yilun Sun, Li Tang, Alyssa Cotton, Jola Dowdy, Randall T. Hayden, Jane S. Hankins, Julia L. Hurwitz
Publikováno v:
Vaccines, Vol 9, Iss 8, p 860 (2021)
Children with sickle cell disease (SCD) suffer life-threatening transient aplastic crisis (TAC) when infected with parvovirus B19. In utero, infection of healthy fetuses may result in anemia, hydrops, and death. Unfortunately, although promising vacc
Externí odkaz:
https://doaj.org/article/f7f113713a25483684b72228951921e3
Publikováno v:
Vaccine. 39:5351-5357
Vaccination is the most effective approach to reduce the substantial morbidity and mortality caused by influenza infection. Vaccine efficacy is highly sensitive to antigenic changes causing differences between circulating and vaccine viruses. Adjuvan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70dc18bfa642c229d744eb2529d2f7ee
https://doi.org/10.1016/j.vaccine.2021.08.021
https://doi.org/10.1016/j.vaccine.2021.08.021
Autor:
Giuseppe Palladino, Cheng Chang, Changkeun Lee, Nedzad Music, Ivna De Souza, Jonathan Nolasco, Samuel Amoah, Pirada Suphaphiphat, Gillis R. Otten, Ethan C. Settembre, Yingxia Wen
Publikováno v:
Molecular therapy. Methodsclinical development. 25
The spike (S) protein of SARS-CoV-2 plays a crucial role in cell entry, and the nucleocapsid (N) protein is highly conserved among human coronavirus homologs. For potentially broad effectiveness against both original virus and emerging variants, we d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::986ee7ddc3b8c1156e256cd951a11a1a
https://pubmed.ncbi.nlm.nih.gov/35345593
https://pubmed.ncbi.nlm.nih.gov/35345593
Autor:
Claudio Ciferri, Sumana Chandramouli, Alexander Leitner, Danilo Donnarumma, Michael A Cianfrocco, Rachel Gerrein, Kristian Friedrich, Yukti Aggarwal, Giuseppe Palladino, Ruedi Aebersold, Nathalie Norais, Ethan C Settembre, Andrea Carfi
Publikováno v:
PLoS Pathogens, Vol 11, Iss 10, p e1005230 (2015)
Human Cytomegalovirus (HCMV) is a major cause of morbidity and mortality in transplant patients and in fetuses following congenital infection. The glycoprotein complexes gH/gL/gO and gH/gL/UL128/UL130/UL131A (Pentamer) are required for HCMV entry in
Externí odkaz:
https://doaj.org/article/3a5daf217abf400db6ba314b6b613072
Autor:
Marua Prevato, Roberta Cozzi, Alfredo Pezzicoli, Anna Rita Taddei, Ilaria Ferlenghi, Avishek Nandi, Emanuele Montomoli, Ethan C Settembre, Sylvie Bertholet, Alessandra Bonci, Francois Legay
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0135383 (2015)
Antibodies (Ab) to neuraminidase (NA) play a role in limiting influenza infection and might help reduce the disease impact. The most widely used serological assay to measure functional anti-NA immune responses is the Enzyme-Linked Lectin Assay (ELLA)
Externí odkaz:
https://doaj.org/article/7c4fe440a9534576b8155731e1e2269f
Autor:
Marua Prevato, Ilaria Ferlenghi, Alessandra Bonci, Yasushi Uematsu, Giulia Anselmi, Fabiola Giusti, Sylvie Bertholet, Francois Legay, John Laird Telford, Ethan C Settembre, Domenico Maione, Roberta Cozzi
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0135474 (2015)
Developing a universal influenza vaccine that induces broad spectrum and longer-term immunity has become an important potentially achievable target in influenza vaccine research and development. Hemagglutinin (HA) and neuraminidase (NA) are the two m
Externí odkaz:
https://doaj.org/article/b36f2c6624fd43618d895857a88d9b2b