Zobrazeno 1 - 10 of 18 pro vyhledávání: '"Ethan Ahler"'
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Akademický článek
Integrating thousands of PTEN variant activity and abundance measurements reveals variant subgroups and new dominant negatives in cancers
Autor: Kenneth A. Matreyek, Jason J. Stephany, Ethan Ahler, Douglas M. Fowler
Publikováno v: Genome Medicine, Vol 13, Iss 1, Pp 1-17 (2021)
Abstract Background PTEN is a multi-functional tumor suppressor protein regulating cell growth, immune signaling, neuronal function, and genome stability. Experimental characterization can help guide the clinical interpretation of the thousands of ge
Externí odkaz: https://doaj.org/article/43d8971ee72b4df69a4e5f58b510d88f
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2
Akademický článek
Doxycycline alters metabolism and proliferation of human cell lines.
Autor: Ethan Ahler, William J Sullivan, Ashley Cass, Daniel Braas, Autumn G York, Steven J Bensinger, Thomas G Graeber, Heather R Christofk
Publikováno v: PLoS ONE, Vol 8, Iss 5, p e64561 (2013)
The tetracycline antibiotics are widely used in biomedical research as mediators of inducible gene expression systems. Despite many known effects of tetracyclines on mammalian cells-including inhibition of the mitochondrial ribosome-there have been f
Externí odkaz: https://doaj.org/article/f5d5669ea35a43eb950b0c11af990ab1
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4
Supplementary Figures 1 - 4 from Metabolomics Strategy Reveals Subpopulation of Liposarcomas Sensitive to Gemcitabine Treatment
Autor: Heather R. Christofk, Hong Wu, William D. Tap, Owen N. Witte, Fritz C. Eilber, Kathleen B. Smith, Matthias R. Benz, Mirielle Riedinger, David Nathanson, Brenna Tam, Ethan Ahler, Daniel Braas
PDF file - 163K, Supplemental Figure 1: Serially passaged liposarcoma xenograft tumors derived from primary tumors and xenograft tumors derived from liposarcoma cell lines both exhibit similar 18F-FDG uptake by PET. Supplemental Figure 2: High grade
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54c237ee7c3b296cba6ac3d9c1c88802
https://doi.org/10.1158/2159-8290.22529046
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5
Supplementary Figures 6-8 from Metabolomics Strategy Reveals Subpopulation of Liposarcomas Sensitive to Gemcitabine Treatment
Autor: Heather R. Christofk, Hong Wu, William D. Tap, Owen N. Witte, Fritz C. Eilber, Kathleen B. Smith, Matthias R. Benz, Mirielle Riedinger, David Nathanson, Brenna Tam, Ethan Ahler, Daniel Braas
PDF file - 85K, Gemcitabine has a cytotoxic effect on three liposarcoma cell lines. Supplemental Figure 7: Gemcitabine is cytotoxic to liposarcoma cell lines and xenograft tumors in mice. Supplemental Figure 8: Gemcitabine decreases tumor growth in s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ba1823d7a40006ffc57b388ba7cec81
https://doi.org/10.1158/2159-8290.22529037
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