Zobrazeno 1 - 10
of 134
pro vyhledávání: '"Ethan A, Lerner"'
Autor:
Aleksandra Dondalska, Elin Rönnberg, Haisha Ma, Sandra Axberg Pålsson, Elin Magnusdottir, Tianle Gao, Lucille Adam, Ethan A. Lerner, Gunnar Nilsson, Malin Lagerström, Anna-Lena Spetz
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Numerous inflammatory skin disorders display a high prevalence of itch. The Mas-related G protein coupled receptor X2 (MRGPRX2) has been shown to modulate itch by inducing non-IgE-mediated mast cell degranulation and the release of endogenous inducer
Externí odkaz:
https://doaj.org/article/e7744e88d4984ca48b72f1c9cb4a62bb
Autor:
Sara Moradi Tuchayi, Ying Wang, Alla Khodorova, Isaac J. Pence, Conor L. Evans, R. Rox Anderson, Ethan A. Lerner, Clifford J. Woolf, Lilit Garibyan
Publikováno v:
Journal of Investigative Dermatology. 143:134-141.e1
Cutaneous pain is a common symptom of skin disease, and available therapies are inadequate. We developed a neural selective and injectable method of cryoneurolysis with ice slurry, which leads to a long-lasting decrease in mechanical pain. The aim of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31fde1c41bf141b08025c94aff7a3802
https://doi.org/10.1016/j.jid.2022.07.018
https://doi.org/10.1016/j.jid.2022.07.018
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e99702 (2014)
Protease-activated receptor-2 is widely expressed in mammalian epithelial, immune and neural tissues. Cleavage of PAR2 by serine proteases leads to self-activation of the receptor by the tethered ligand SLIGRL. The contribution of other classes of pr
Externí odkaz:
https://doaj.org/article/b9e79f0b04374c5eb154a0fb951720ed
Publikováno v:
The British journal of dermatologyReferences. 183(5)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::649fca8d40d402a2cc0d5470cd97d65a
https://pubmed.ncbi.nlm.nih.gov/32407578
https://pubmed.ncbi.nlm.nih.gov/32407578
Autor:
Ethan A. Lerner, Melissa S. Lee
Publikováno v:
Journal of Investigative Dermatology. 139:282-284
Itch, inflammation, and atopic dermatitis are associated with activation of PAR2. Affecting PAR2 activity presents a number of challenges. Here, a cell-penetrating peptide, termed a pepducin, circumvents these challenges by preventing the receptor fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90e5e084435702d1117c00d4a4ecd864
https://doi.org/10.1016/j.jid.2018.09.008
https://doi.org/10.1016/j.jid.2018.09.008
Autor:
Ethan A. Lerner, Vemuri B. Reddy
Publikováno v:
Journal of Biological Chemistry. 292:17399-17406
Cysteine and serine proteases function via protease-activated and mas-related G-protein–coupled receptors (Mrgprs) to contribute to allergy and inflammation. Der p1 is a cysteine protease and major allergen from the house dust mite and is associate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6073e9d7ffafefe95b76b5bda706a16
https://doi.org/10.1074/jbc.m117.787887
https://doi.org/10.1074/jbc.m117.787887
Autor:
Ferda Cevikbas, Ethan A. Lerner
Publikováno v:
Rosacea ISBN: 9783030520960
The pathophysiology underlying rosacea is an active area of investigation. A variety of mediators and mechanisms that trigger disease onset and progression have been implicated in this phenotypically heterogenous and clinically diverse condition. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b9f9c8f4d9f7b34733e991fef52fc4b
https://doi.org/10.1007/978-3-030-52097-7_2
https://doi.org/10.1007/978-3-030-52097-7_2
Autor:
Ethan A. Lerner
Publikováno v:
Dermatologic Clinics. 36:175-177
Chronic itch is a clinically challenging yet scientifically remarkable and complex process. Increasing understanding of the pathophysiology of chronic itch is leading to targeted therapeutic approaches that are now dramatically improving quality of l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::360c23ae200b454183eeecc159520152
https://doi.org/10.1016/j.det.2018.02.001
https://doi.org/10.1016/j.det.2018.02.001
Autor:
Ferda Cevikbas, Ethan A. Lerner
Publikováno v:
Physiol Rev
Itch is a topic to which everyone can relate. The physiological roles of itch are increasingly understood and appreciated. The pathophysiological consequences of itch impact quality of life as much as pain. These dynamics have led to increasingly dee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43310b1cf3e56baa6dcec09c137ca0c5
https://europepmc.org/articles/PMC7474262/
https://europepmc.org/articles/PMC7474262/
Publikováno v:
Journal of Investigative Dermatology. 141:S118
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f8f08fee129af1f10ba55f692ded53c
https://doi.org/10.1016/j.jid.2021.02.712
https://doi.org/10.1016/j.jid.2021.02.712