An Audit and Comparison of pH, Measured Concentration, and Particulate Matter in Mannitol and Hypertonic Saline Solutions

Autor: Christopher J. Carr, Jonathan Scoville, James Ruble, Chad Condie, Gary Davis, Candace L. Floyd, Logan Kelly, Ken Monson, Ethan Reichert, Buse Sarigul, Gregory W. J. Hawryluk

Publikováno v: Frontiers in Neurology, Vol 12 (2021)

Background: The preferred hyperosmolar therapy remains controversial. Differences in physical properties such as pH and osmolality may be important considerations in hyperosmolar agent selection. We aimed to characterize important physical properties

Externí odkaz: https://doaj.org/article/41e3d09a6fc647f88d4bd0d304229f4e

ISCA2 inhibition decreases HIF and induces ferroptosis in clear cell renal carcinoma

Autor: Yangsook Song Green, Maria C. Ferreira dos Santos, Daniel Fuja, Ethan Reichert, Alexandre R. Campos, Sophie J. Cowman, Jessica Kohan, Sheryl R. Tripp, Elizabeth A. Leibold, Deepika Sirohi, Neeraj Agarwal, Xiaohui Liu, Mei Yee Koh

Clear cell renal cell carcinoma (ccRCC), the most common form of kidney cancer, is typically initiated by inactivation of the von Hippel Lindau (VHL) gene, which results in the constitutive activation of the hypoxia inducible factors, HIF-1α and HIF

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8768eab3002c71c357885b55e5ec48cd
https://doi.org/10.1101/2022.06.01.494206

An Audit and Comparison of pH, Measured Concentration, and Particulate Matter in Mannitol and Hypertonic Saline Solutions

Autor: Kenneth L. Monson, Jonathan P Scoville, Christopher Carr, Ethan Reichert, Gary Davis, James H. Ruble, Buse Sarigul, Chad Condie, Logan Kelly, Candace L. Floyd, Gregory W.J. Hawryluk

Publikováno v: Frontiers in Neurology, Vol 12 (2021)
Frontiers in Neurology

Background: The preferred hyperosmolar therapy remains controversial. Differences in physical properties such as pH and osmolality may be important considerations in hyperosmolar agent selection. We aimed to characterize important physical properties

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9cb6ece604d5e94e890c21267b07f96
https://www.frontiersin.org/articles/10.3389/fneur.2021.667842/full

CNS inflammation and neurodegeneration: sequelae of peripheral inoculation with spinal cord tissue in rat

Autor: Gregory W.J. Hawryluk, Ethan Reichert, Jenna Faulkner, Brielle Reichert, Joshua A. Sonnen, Lonnie Schneider

Publikováno v: Journal of neurosurgery. 132(3)

OBJECTIVERecent research demonstrates that victims of spinal cord injury (SCI) are at increased risk for dementia and that encephalitis can occur as a consequence of isolated SCI. We theorize that autoimmunity to the central nervous system (CNS) coul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35d64fbcd87f720ae4cdb469969a0c86
https://pubmed.ncbi.nlm.nih.gov/30717048

Mouse Plasminogen Has Oxidized Phosphatidylcholine Adducts That Are Not Metabolized by Lipoprotein-Associated Phospholipase A2 under Basal Conditions

Autor: Diana M. Stafforini, Ethan Reichert, Ditta Pfaffinger, Angelo M. Scanu, Celina Edelstein

Publikováno v: International Journal of Molecular Sciences, Vol 11, Iss 12, Pp 5339-5347 (2010)
International Journal of Molecular Sciences
Volume 11
Issue 12
Pages 5339-5347

We previously showed that plasminogen (Plg) isolated from the plasma of normal human subjects contains 1-2 moles of oxidized phosphatidylcholine (oxPtdPC) adducts/mole of protein. Moreover, we suggested that these species are generated at the hepatic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c6a028f002762282a25bfb97f7ca012
https://doi.org/10.3390/ijms11125339