In vitro cytotoxic potential of extracts from Aristolochia foetida Kunth against MCF-7 and bMECs cell lines

Autor: Alejandra Ochoa-Zarzosa, Lidia Beiza‐Granados, Joel E. López-Meza, Juan D. Hernández-Hernández, Martín A. Lerma-Herrera, Hugo A. García-Gutiérrez, Judit A. Aviña-Verduzco

Publikováno v: Saudi Journal of Biological Sciences
Saudi Journal of Biological Sciences, Vol 28, Iss 12, Pp 7082-7089 (2021)

The aim of this study was to evaluate the cytotoxic potential of Aristolochia foetida Kunth. Stems and leaves of A. foetida Kunth (Aristolochiaceae) have never been investigated pharmacologically. Recent studies of species of the Aristolochiaceae fam

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0affe22beee7991ad54fd6f79370f5ee
http://europepmc.org/articles/PMC8626259

Defining the role of CFTR channel blocker and ClC-2 activator in DNBS induced gastrointestinal inflammation

Autor: Vijay R. Chidrawar, Bader Alsuwayt

Publikováno v: Saudi Pharmaceutical Journal : SPJ

In the present study, we have investigated and/or compared the role of glibenclamide, G as cystic fibrosis transmembrane conductance regulator (CFTR) inhibitor, and lubiprostone, L as chloride channel-2 (ClC-2) activator in the 2,4-dinitrobenzene sul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae14bfe965e654468af30a05663d9b28
https://doi.org/10.1016/j.jsps.2021.02.005

Development of 2-(4-pyridyl)-benzimidazoles as PKN2 chemical tools to probe cancer

Autor: Katlin B. Massirer, Lewis E. Pennicott, Fiona Scott, Jonathan M. Elkins, Simon E. Ward, Tristan Reuillon, A.M. Fala

Publikováno v: Bioorganic & Medicinal Chemistry Letters

Graphical abstract
Kinases are signalling proteins which have proven to be successful targets for the treatment of a variety of diseases, predominantly in cancers. However, only a small proportion of kinases (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee1561d0a57fd94895c128a26cfe5805
https://doi.org/10.1016/j.bmcl.2020.127040

'CHOICES': An acronym to aid in delineating potential causes of non-metabolic, non-infectious acute toxic leukoencephalopathy

Autor: Can Özütemiz, Frederick Ott, Mark C. Oswood, Alexander M. McKinney, Yasemin Koksel, Zuzan Cayci, Jeffrey B. Rykken

Publikováno v: European Journal of Radiology Open
European Journal of Radiology Open, Vol 6, Iss, Pp 243-257 (2019)

Highlights • Recognition the etiologies of ATL is important due to its potentially reversible nature after treatment or removal of the toxin. • “CHOICES” is useful to memorize etiologies associated with PVWM injury in non-metabolic and non-in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d8fbed62f668eb67d49f0c57868d469
https://doi.org/10.1016/j.ejro.2019.06.005

Application of Quality by Design to the robust preparation of a liposomal GLA formulation by DELOS-susp method

Autor: Susanne Resch, Teresa Lizarraga, Miriam Royo, Ibane Abasolo, Simó Schwartz, Marta Alcaina-Hernando, Judit Tomsen-Melero, Dganit Danino, Christa Schimpel, Alba Córdoba, Jaume Veciana, Jannik Nedergaard Pedersen, Jan Skov Pedersen, Elisabet González-Mira, Andreas Falk, Albert Font, Nora Ventosa, Rosa Mendoza, José-Luis Corchero, Santi Sala, Elena García-Fruitós, Natalia García-Aranda, Edgar Cristóbal-Lecina, Josep Merlo-Mas, Daniel Pulido, Andreu Soldevila

Publikováno v: Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
The Journal of Supercritical Fluids
Merlo-Mas, J, Tomsen-Melero, J, Corchero, J L, González-Mira, E, Font, A, Pedersen, J N, García-Aranda, N, Cristóbal-Lecina, E, Alcaina-Hernando, M, Mendoza, R, Garcia-Fruitós, E, Lizarraga, T, Resch, S, Schimpel, C, Falk, A, Pulido, D, Royo, M, Schwartz, S, Abasolo, I, Pedersen, J S, Danino, D, Soldevila, A, Veciana, J, Sala, S, Ventosa, N & Córdoba, A 2021, ' Application of Quality by Design to the robust preparation of a liposomal GLA formulation by DELOS-susp method ', Journal of Supercritical Fluids, vol. 173, 105204 . https://doi.org/10.1016/j.supflu.2021.105204
IRTA Pubpro. Open Digital Archive
Institut de Recerca i Tecnologia Agroalimentàries (IRTA)
Digital.CSIC. Repositorio Institucional del CSIC
instname

Fabry disease is a lysosomal storage disease arising from a deficiency of the enzyme α-galactosidase A (GLA). The enzyme deficiency results in an accumulation of glycolipids, which over time, leads to cardiovascular, cerebrovascular, and renal disea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0d0009fd48d1b291e4b8ff9aea7bb39
https://ddd.uab.cat/record/247506