The Early Endocytosis Gene PAL1 Contributes to Stress Tolerance and Hyphal Formation in Candida albicans .

Autor: Yu M; Thayer School of Engineering at Dartmouth, Dartmouth College, Hanover, NH 03755, USA.; Medicine Service, White River Junction VA Medical Center, Hartford, VT 05009, USA., Ma D; Medicine Service, White River Junction VA Medical Center, Hartford, VT 05009, USA.; Department of Biological Sciences, Dartmouth College, Hanover, NH 03755, USA., Eszterhas S; Medicine Service, White River Junction VA Medical Center, Hartford, VT 05009, USA.; Department of Medicine, Geisel School of Medicine, Dartmouth College, Hanover, NH 03755, USA., Rollenhagen C; Department of Medicine, Geisel School of Medicine, Dartmouth College, Hanover, NH 03755, USA., Lee SA; Department of Medicine, Geisel School of Medicine, Dartmouth College, Hanover, NH 03755, USA.

Publikováno v: Journal of fungi (Basel, Switzerland) [J Fungi (Basel)] 2023 Nov 10; Vol. 9 (11). Date of Electronic Publication: 2023 Nov 10.

Functional Deimmunization of Botulinum Neurotoxin Protease Domain via Computationally Driven Library Design and Ultrahigh-Throughput Screening.

Autor: Fang Y; Thayer School of Engineering, Dartmouth, Hanover, New Hampshire 03755, United States.; Department of Urology, Boston Children's Hospital, Boston, Massachusetts 02115, United States.; Department of Microbiology and Department of Surgery, Harvard Medical School, Boston, Massachusetts 02115, United States., Chang AY; Thayer School of Engineering, Dartmouth, Hanover, New Hampshire 03755, United States., Verma D; Department of Computer Science, Dartmouth, Hanover, New Hampshire 03755, United States., Miyashita SI; Department of Urology, Boston Children's Hospital, Boston, Massachusetts 02115, United States.; Department of Microbiology and Department of Surgery, Harvard Medical School, Boston, Massachusetts 02115, United States.; Department of Food, Aroma and Cosmetic Chemistry, Tokyo University of Agriculture, 196 Yasaka, Abashiri 099-2493, Japan., Eszterhas S; Thayer School of Engineering, Dartmouth, Hanover, New Hampshire 03755, United States., Lee PG; Department of Urology, Boston Children's Hospital, Boston, Massachusetts 02115, United States.; Department of Microbiology and Department of Surgery, Harvard Medical School, Boston, Massachusetts 02115, United States., Shen Y; Department of Urology, Boston Children's Hospital, Boston, Massachusetts 02115, United States.; Department of Microbiology and Department of Surgery, Harvard Medical School, Boston, Massachusetts 02115, United States., Davis LR; Thayer School of Engineering, Dartmouth, Hanover, New Hampshire 03755, United States., Dong M; Department of Urology, Boston Children's Hospital, Boston, Massachusetts 02115, United States.; Department of Microbiology and Department of Surgery, Harvard Medical School, Boston, Massachusetts 02115, United States., Bailey-Kellogg C; Department of Computer Science, Dartmouth, Hanover, New Hampshire 03755, United States., Griswold KE; Thayer School of Engineering, Dartmouth, Hanover, New Hampshire 03755, United States.

Publikováno v: ACS synthetic biology [ACS Synth Biol] 2023 Jan 20; Vol. 12 (1), pp. 153-163. Date of Electronic Publication: 2023 Jan 09.

Candida albicans ENT2 Contributes to Efficient Endocytosis, Cell Wall Integrity, Filamentation, and Virulence.

Autor: Rollenhagen C; Medicine Service, White River Junction VA Medical Center, White River Junction, Vermont, USA.; Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA., Agyeman H; Medicine Service, White River Junction VA Medical Center, White River Junction, Vermont, USA., Eszterhas S; Medicine Service, White River Junction VA Medical Center, White River Junction, Vermont, USA.; Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA., Lee SA; Medicine Service, White River Junction VA Medical Center, White River Junction, Vermont, USA.; Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA.

Publikováno v: MSphere [mSphere] 2021 Oct 27; Vol. 6 (5), pp. e0070721. Date of Electronic Publication: 2021 Sep 29.

Deimmunized Lysostaphin Synergizes with Small-Molecule Chemotherapies and Resensitizes Methicillin-Resistant Staphylococcus aureus to β-Lactam Antibiotics.

Autor: Fang Y; Thayer School of Engineering, Dartmouth College, Hanover, New Hampshire, USA., Kirsch JR; Thayer School of Engineering, Dartmouth College, Hanover, New Hampshire, USA., Li L; The Lundquist Institute at Harbor-UCLA Medical Center, Torrance, California, USA., Brooks SA; Thayer School of Engineering, Dartmouth College, Hanover, New Hampshire, USA., Heim S; Thayer School of Engineering, Dartmouth College, Hanover, New Hampshire, USA., Tan C; Thayer School of Engineering, Dartmouth College, Hanover, New Hampshire, USA., Eszterhas S; Thayer School of Engineering, Dartmouth College, Hanover, New Hampshire, USA., Cheng HD; Lyticon LLC, Lebanon, New Hampshire, USA., Zhao H; Thayer School of Engineering, Dartmouth College, Hanover, New Hampshire, USA., Xiong YQ; The Lundquist Institute at Harbor-UCLA Medical Center, Torrance, California, USA., Griswold KE; Thayer School of Engineering, Dartmouth College, Hanover, New Hampshire, USA karl.e.griswold@dartmouth.edu.; Lyticon LLC, Lebanon, New Hampshire, USA.; Stealth Biologics, LLC, Lebanon, New Hampshire, USA.

Publikováno v: Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2021 Feb 17; Vol. 65 (3). Date of Electronic Publication: 2021 Feb 17 (Print Publication: 2021).

The Role of Secretory Pathways in Candida albicans Pathogenesis.

Autor: Rollenhagen C; Medicine Service, White River Junction VA Medical Center, White River Junction, VT 05009, USA.; Department of Medicine, Geisel School of Medicine at Dartmouth, Hanover, NH 03755, USA., Mamtani S; Medicine Service, White River Junction VA Medical Center, White River Junction, VT 05009, USA., Ma D; Medicine Service, White River Junction VA Medical Center, White River Junction, VT 05009, USA.; Dartmouth College, Hanover, NH 03755, USA;., Dixit R; Medicine Service, White River Junction VA Medical Center, White River Junction, VT 05009, USA.; Dartmouth College, Hanover, NH 03755, USA;., Eszterhas S; Medicine Service, White River Junction VA Medical Center, White River Junction, VT 05009, USA.; Department of Medicine, Geisel School of Medicine at Dartmouth, Hanover, NH 03755, USA., Lee SA; Medicine Service, White River Junction VA Medical Center, White River Junction, VT 05009, USA.; Department of Medicine, Geisel School of Medicine at Dartmouth, Hanover, NH 03755, USA.

Publikováno v: Journal of fungi (Basel, Switzerland) [J Fungi (Basel)] 2020 Feb 24; Vol. 6 (1). Date of Electronic Publication: 2020 Feb 24.