Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Eszter Lazar-Molnar"'
Autor:
Kimberly C. Dibb, Cassandra Monds, Tracie Profaizer, Eszter Lazar-Molnar, John Andreasen, Holly Bethers, Julio C. Delgado
Publikováno v:
The Journal of Applied Laboratory Medicine. 6:1221-1227
Background Due to the strong association between ankylosing spondylitis and Human Leukocyte Antigen (HLA)-B27, accurate identification of HLA-B27 is important in the diagnosis of patients with suspected spondyloarthritides. For this study, we compare
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b92eceb45a80941e903205e23fc496d
https://doi.org/10.1093/jalm/jfab046
https://doi.org/10.1093/jalm/jfab046
Publikováno v:
Human Immunology. 81:354-360
HLA associations have been linked to many diseases and are important for risk assessment of drug hypersensitivity reactions. The increasing number of HLA alleles discovered generated a list of ambiguities that cannot be resolved with the current clin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30e7cf07fd74c27d68a94ccc64232e6e
https://doi.org/10.1016/j.humimm.2020.05.001
https://doi.org/10.1016/j.humimm.2020.05.001
Autor:
Rebecca L. Parker, Julio C. Delgado, Eszter Lazar-Molnar, Frederick G. Strathmann, Igor Y. Pavlov
Publikováno v:
Journal of Immunological Methods. 470:33-39
TNF antagonists such as infliximab are effective for the treatment of several inflammatory and autoimmune diseases. Recent clinical studies have advocated the importance of measuring trough infliximab levels to guide treatment decisions. We have deve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::639134992fc3de44a3b660bc5dffa9f5
https://doi.org/10.1016/j.jim.2019.04.008
https://doi.org/10.1016/j.jim.2019.04.008
Publikováno v:
Clinical chemistry. 66(10)
Background Immunoassays based on label-free technologies (label-free immunoassay [LFIA]) offer an innovative approach to clinical diagnostics and demonstrate great promise for therapeutic drug monitoring (TDM) of monoclonal antibody (mAb) drugs. An L
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33096a4d16234e9afaebb287b97acc40
https://pubmed.ncbi.nlm.nih.gov/32918468
https://pubmed.ncbi.nlm.nih.gov/32918468
Comparison of Clinical Laboratory Assays for Measuring Serum Infliximab and Antibodies to Infliximab
Publikováno v:
The Journal of Applied Laboratory Medicine. 2:893-903
Background Infliximab (IFX) is a chimeric monoclonal antibody targeting tumor necrosis factor-α, used for the management of autoimmune and inflammatory diseases. Immunogenicity to this protein drug may lead to therapeutic failure. Laboratory testing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52081321f981dcc21033363db13338f7
https://doi.org/10.1373/jalm.2017.024869
https://doi.org/10.1373/jalm.2017.024869
Autor:
Thomas J. Quinn, Eszter Lazar-Molnar, Chandan Guha, Indranil Basu, Steven C. Almo, Edith Palmieri, Eliezer Sylvestre, Stanley G. Nathenson, Udupi A. Ramagopal, Lisa Scandiuzzi
Publikováno v:
EBioMedicine, Vol 17, Iss C, Pp 30-44 (2017)
EBioMedicine
EBioMedicine
Programmed Cell Death-1 (PD-1) is an inhibitory immune receptor, which plays critical roles in T cell co-inhibition and exhaustion upon binding to its ligands PD-L1 and PD-L2. We report the crystal structure of the human PD-1 ectodomain and the mappi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73522bca8d582a148e97b65560d02861
http://www.sciencedirect.com/science/article/pii/S2352396417300622
http://www.sciencedirect.com/science/article/pii/S2352396417300622
Publikováno v:
HLA. 88:14-24
Implementation of human leukocyte antigen (HLA) genotyping by next-generation sequencing (NGS) in the clinical lab brings new challenges to the laboratories performing this testing. With the advent of commercially available HLA-NGS typing kits, labs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a40cacad09b98a704c26056acbba2c19
https://doi.org/10.1111/tan.12850
https://doi.org/10.1111/tan.12850
Autor:
Melissa R. Snyder, Eszter Lazar-Molnar
Publikováno v:
Clinics in laboratory medicine. 38(4)
Celiac disease is an autoimmune disease affecting the small intestine, triggered by gluten sensitization in genetically susceptible individuals worldwide. Celiac disease development is strongly linked to the presence of HLA-DQ2 and/or DQ8, which pres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a44a3c787faf2f921d3dba2d4b54f66b
https://pubmed.ncbi.nlm.nih.gov/30420059
https://pubmed.ncbi.nlm.nih.gov/30420059
Autor:
Carl T. Wittwer, Patricia R. Slev, Eszter Lazar-Molnar, Lisa K. Peterson, Anne E. Tebo, Adam P. Barker, Cheryl M Charlton, Nahla M. Heikal, Harry Hill, Eugene V. Ravkov, Karl V. Voelkerding, Julio C. Delgado, Attila Kumánovics
Publikováno v:
Cytometry. Part B, Clinical cytometry. 96(4)
Background Mass cytometry can differentiate more channels than conventional flow cytometry. However, for clinical use, standardization and agreement with well-established methods is paramount. We compared mass cytometry to standard clinical flow cyto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cebd40b28edc60cdfa5e4255c67851be
https://pubmed.ncbi.nlm.nih.gov/31173473
https://pubmed.ncbi.nlm.nih.gov/31173473
Autor:
Julio C. Delgado, Eszter Lazar-Molnar
Publikováno v:
Clinical chemistry. 65(3)
BACKGROUND Monoclonal antibody therapeutics (MATs) represent a rapidly expanding class of biological drugs used to treat a variety of diseases. The widespread use of MATs increasingly affects clinical laboratory medicine. CONTENT This review provides
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::439f73f2a568d8a7aae25d72bf47ef8a
https://pubmed.ncbi.nlm.nih.gov/30377156
https://pubmed.ncbi.nlm.nih.gov/30377156