Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Eszter Emri"'
Autor:
Eszter Emri, Oisin Cappa, Caoimhe Kelly, Elod Kortvely, John Paul SanGiovanni, Brian S. McKay, Arthur A. Bergen, David A. Simpson, Imre Lengyel
Publikováno v:
Cells, Vol 12, Iss 5, p 773 (2023)
Zinc supplementation has been shown to be beneficial to slow the progression of age-related macular degeneration (AMD). However, the molecular mechanism underpinning this benefit is not well understood. This study used single-cell RNA sequencing to i
Externí odkaz:
https://doaj.org/article/3ed1ecb4cff647cbad6eee0dd785ff03
Autor:
Eszter Emri, Elod Kortvely, Sascha Dammeier, Franziska Klose, David Simpson, EYE-RISK Consortium, Anneke I. den Hollander, Marius Ueffing, Imre Lengyel
Publikováno v:
Nutrients, Vol 12, Iss 10, p 3051 (2020)
In age-related macular degeneration (AMD), both systemic and local zinc levels decline. Elevation of zinc in clinical studies delayed the progression to end-stage AMD. However, the molecular pathways underpinning this beneficial effect are not yet id
Externí odkaz:
https://doaj.org/article/a700fab388e14ef7800bc068ff5c1937
Autor:
Gábor Boros, Edit Miko, Hiromi Muramatsu, Drew Weissman, Eszter Emri, Gijsbertus T J van der Horst, Andrea Szegedi, Irén Horkay, Gabriella Emri, Katalin Karikó, Éva Remenyik
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0131141 (2015)
Major biological effects of UVB are attributed to cyclobutane pyrimidine dimers (CPDs), the most common photolesions formed on DNA. To investigate the contribution of CPDs to UVB-induced changes of gene expression, a model system was established by t
Externí odkaz:
https://doaj.org/article/c96b213c8ca1423eaabfe8cb62193300
Autor:
Anita de Breuk, Ilhan E. Acar, Eveline Kersten, Mascha M.V.A.P. Schijvenaars, Johanna M. Colijn, Lonneke Haer-Wigman, Bjorn Bakker, Sarah de Jong, Magda A. Meester-Smoor, Timo Verzijden, Tom O.A.R. Missotten, Jordi Monés, Marc Biarnés, Daniel Pauleikhoff, Hans W. Hense, Rufino Silva, Sandrina Nunes, Joana B. Melo, Sascha Fauser, Carel B. Hoyng, Marius Ueffing, Marieke J.H. Coenen, Caroline C.W. Klaver, Anneke I. den Hollander, Soufiane Ajana, Audrey Cougnard-Grégoire, Cécile Delcourt, Bénédicte M.J. Merle, Blanca Arango-Gonzalez, Sascha Dammeier, Sigrid Diether, Sabina Honisch, Ellen Kilger, Tanja Endermann, Markus Zumbansen, Franz Badura, Berta De la Cerda, Anna Borrell, Lucia L. Ferraro, Míriam Garcia, Eduardo Rodríguez, A. Ikram, Magda Meester-Smoor, Johannes Vingerling, Thomas J. Heesterbeek, Eiko K. de Jong, I. Erkin Acar, Eszter Emri, Imre Lengyel, Hanno Langen, Everson Nogoceke, Tunde Peto, Phil Luthert, Frances M. Pool
Publikováno v:
Ophthalmology. 128:1604-1617
Purpose To develop a genotype assay to assess associations with common and rare age-related macular degeneration (AMD) risk variants, to calculate an overall genetic risk score (GRS), and to identify potential misdiagnoses with inherited macular dyst
Publikováno v:
Acta Ophthalmologica. 100
Autor:
Reinier Bakker, Ellie L. Wagstaff, Charlotte C. Kruijt, Eszter Emri, Clara D.M. van Karnebeek, Michael B. Hoffmann, Brian P. Brooks, Camiel J.F. Boon, Lluis Montoliu, Maria M. van Genderen, Arthur A. Bergen
Publikováno v:
Bakker, R, Wagstaff, P E, Kruijt, C C, Emri, E, van Karnebeek, C D M, Hoffmann, M B, Brooks, B P, Boon, C J F, Montoliu, L, van Genderen, M M & Bergen, A A 2022, ' The retinal pigmentation pathway in human albinism : Not so black and white ', Progress in Retinal and Eye Research, vol. 91, 101091 . https://doi.org/10.1016/j.preteyeres.2022.101091
Progress in Retinal and Eye Research, 91. Elsevier B.V.
Progress in Retinal and Eye Research, 91. PERGAMON-ELSEVIER SCIENCE LTD
Progress in Retinal and Eye Research, 91. Elsevier B.V.
Progress in Retinal and Eye Research, 91. PERGAMON-ELSEVIER SCIENCE LTD
Albinism is a pigment disorder affecting eye, skin and/or hair. Patients usually have decreased melanin in affected tissues and suffer from severe visual abnormalities, including foveal hypoplasia and chiasmal misrouting. Combining our data with thos
Autor:
Eszter Emri, Oisin Cappa, Caoimhe Kelly, Elod Kortvely, John Paul SanGiovanni, Brian S. McKay, Arthur A. Bergen, David A. Simpson, Imre Lengyel
Publikováno v:
Cells, 12(5):773. Multidisciplinary Digital Publishing Institute (MDPI)
Emri, E, Cappa, O, Kelly, C, Kortvely, E, SanGiovanni, J P, McKay, B S, Bergen, A A, Simpson, D A & Lengyel, I 2023, ' Zinc supplementation induced transcriptional changes in primary human retinal pigment epithelium: a single-cell RNA sequencing study to understand age-related macular degeneration ', Cells, vol. 12, no. 5, 773 . https://doi.org/10.3390/cells12050773
Cells
Volume 12
Issue 5
Pages: 773
Emri, E, Cappa, O, Kelly, C, Kortvely, E, SanGiovanni, J P, McKay, B S, Bergen, A A, Simpson, D A & Lengyel, I 2023, ' Zinc supplementation induced transcriptional changes in primary human retinal pigment epithelium: a single-cell RNA sequencing study to understand age-related macular degeneration ', Cells, vol. 12, no. 5, 773 . https://doi.org/10.3390/cells12050773
Cells
Volume 12
Issue 5
Pages: 773
Zinc supplementation had been shown to be beneficial to slow the progression of age-related macular degeneration (AMD). However, the molecular mechanism underpinning this benefit is not well understood. In this study, we used single-cell RNA sequenci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bed4012bab0e44ffd4deccb7b05a9cfc
https://doi.org/10.1101/2022.09.01.504514
https://doi.org/10.1101/2022.09.01.504514
Autor:
İlhan E. Acar, Laura Lores-Motta, Johanna M. Colijn, Magda A. Meester-Smoor, Timo Verzijden, Audrey Cougnard-Gregoire, Soufiane Ajana, Benedicte M.J. Merle, Anita de Breuk, Thomas J. Heesterbeek, Erik van den Akker, Mohamed R. Daha, Birte Claes, Daniel Pauleikhoff, Hans-Werner Hense, Cornelia M. van Duijn, Sascha Fauser, Carel B. Hoyng, Cécile Delcourt, Caroline C.W. Klaver, Tessel E. Galesloot, Anneke I. den Hollander, Blanca Arango-Gonzalez, Angela Armento, Franz Badura, Vaibhav Bhatia, Shomi S. Bhattacharya, Marc Biarnés, Anna Borrell, Sofia M. Calado, Sascha Dammeier, Berta De la Cerda, Francisco J. Diaz-Corrales, Sigrid Diether, Eszter Emri, Tanja Endermann, Lucia L. Ferraro, Míriam Garcia, Sabina Honisch, Ellen Kilger, Elod Kortvely, Claire Lastrucci, Hanno Langen, Imre Lengyel, Phil Luthert, Jordi Monés, Everson Nogoceke, Tunde Peto, Frances M. Pool, Eduardo Rodriguez-Bocanegra, Luis Serrano, Jose Sousa, Eric Thee, Marius Ueffing, Karl U. Ulrich Bartz-Schmidt, Markus Zumbansen
Publikováno v:
Ophthalmology. 127:1693-1709
Purpose: The current study aimed to identify metabolites associated with age-related macular degeneration (AMD) by performing the largest metabolome association analysis in AMD to date, as well as aiming to determine the effect of AMD-associated gene
Autor:
Ana Alvarez‐Barrios, Lydia Álvarez, Montserrat García, Eszter Emri, Imre Lengyel, Rosario Pereiro, Héctor González‐Iglesias
Publikováno v:
Acta Ophthalmologica. 100
Autor:
Johanna M. Colijn, Anneke I. den Hollander, Ayse Demirkan, Audrey Cougnard-Grégoire, Timo Verzijden, Eveline Kersten, Magda A. Meester-Smoor, Benedicte M.J. Merle, Grigorios Papageorgiou, Shahzad Ahmad, Monique T. Mulder, Miguel Angelo Costa, Pascale Benlian, Geir Bertelsen, Alain M. Bron, Birte Claes, Catherine Creuzot-Garcher, Maja Gran Erke, Sascha Fauser, Paul J. Foster, Christopher J. Hammond, Hans-Werner Hense, Carel B. Hoyng, Anthony P. Khawaja, Jean-Francois Korobelnik, Stefano Piermarocchi, Tatiana Segato, Rufino Silva, Eric H. Souied, Katie M. Williams, Cornelia M. van Duijn, Cécile Delcourt, Caroline C.W. Klaver, Niyazi Acar, Lebriz Altay, Eleftherios Anastosopoulos, Augusto Azuara-Blanco, Tos Berendschot, Arthur Bergen, Christine Binquet, Alan Bird, Martin Bobak, Morten Bøgelund Larsen, Camiel Boon, Rupert Bourne, Lionel Brétillon, Rebecca Broe, Alain Bron, Gabrielle Buitendijk, Maria Luz Cachulo, Vittorio Capuano, Isabelle Carrière, Usha Chakravarthy, Michelle Chan, Petrus Chang, Johanna Colijn, Angela Cree, Phillippa Cumberland, José Cunha-Vaz, Vincent Daien, Eiko De Jong, Gabor Deak, Marie-Noëlle Delyfer, Anneke den Hollander, Martha Dietzel, Pedro Faria, Claudia Farinha, Robert Finger, Astrid Fletcher, Paul Foster, Panayiota Founti, Theo Gorgels, Jakob Grauslund, Franz Grus, Christopher Hammond, Thomas Heesterbeek, Manuel Hermann, René Hoehn, Ruth Hogg, Frank Holz, Carel Hoyng, Nomdo Jansonius, Sarah Janssen, Eiko de Jong, Anthony Khawaja, Caroline Klaver, Jean-François Korobelnik, Julia Lamparter, Mélanie Le Goff, Terho Lehtimäki, Irene Leung, Andrew Lotery, Matthias Mauschitz, Magda Meester, Bénédicte Merle, Verena Meyer zu Westrup, Edoardo Midena, Stefania Miotto, Alireza Mirshahi, Sadek Mohan-Saïd, Michael Mueller, Alyson Muldrew, Joaquim Murta, Stefan Nickels, Sandrina Nunes, Christopher Owen, Tunde Peto, Norbert Pfeiffer, Elena Prokofyeva, Jugnoo Rahi, Olli Raitakari, Franziska Rauscher, Luisa Ribeiro, Marie-Bénédicte Rougier, Alicja Rudnicka, José Sahel, Aggeliki Salonikiou, Clarisa Sanchez, Tina Schick, Steffen Schmitz-Valckenberg, Alexander Schuster, Cédric Schweitzer, Jasmin Shehata, Giuliana Silvestri, Christian Simader, Eric Souied, Martynas Speckauskas, Henriet Springelkamp, Robyn Tapp, Fotis Topouzis, Elisa van Leeuwen, Virginie Verhoeven, Hans Vingerling, Therese Von Hanno, Katie Williams, Christian Wolfram, Jennifer Yip, Jennyfer Zerbib, Soufiane Ajana, Blanca Arango-Gonzalez, Verena Arndt, Vaibhav Bhatia, Shomi S. Bhattacharya, Marc Biarnés, Anna Borrell, Sebastian Bühren, Sofia M. Calado, Sascha Dammeier, Eiko K. de Jong, Berta De la Cerda, Francisco J. Diaz-Corrales, Sigrid Diether, Eszter Emri, Tanja Endermann, Lucia L. Ferraro, Míriam Garcia, Thomas J. Heesterbeek, Sabina Honisch, Ellen Kilger, Hanno Langen, Imre Lengyel, Phil Luthert, Cyrille Maugeais, Magda Meester-Smoor, Bénédicte M.J. Merle Inserm, Jordi Monés, Everson Nogoceke, Frances M. Pool, Eduardo Rodríguez, Marius Ueffing, Karl U. Ulrich Bartz-Schmidt, Elisabeth M. van Leeuwen, Markus Zumbansen
Publikováno v:
Ophthalmology. 126:393-406
PURPOSE: Genetic and epidemiologic studies have shown that lipid genes and High Density Lipoproteins (HDL) are implicated in age-related macular degeneration (AMD). We studied circulating lipid levels in relation to AMD in a large European dataset, a