Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Eszter, Lajkó"'
Publikováno v:
ACS Omega, Vol 9, Iss 6, Pp 6894-6900 (2024)
Externí odkaz:
https://doaj.org/article/5d9ff418dc294e90a5ae304cf9a25ecf
Publikováno v:
FEBS Open Bio, Vol 13, Iss 12, Pp 2356-2366 (2023)
Traditional drug screening methods use monolayer (2D) tumor cell cultures, which lack basic features of tumor complexity. As an alternative, 3D hydrogels have begun to emerge as simple, time‐, and cost‐saving systems. One of the most promising ca
Externí odkaz:
https://doaj.org/article/2baabdf118484cfe978a40135566e00e
Autor:
Zsófia Szász, Kata Nóra Enyedi, Angéla Takács, Nóra Fekete, Gábor Mező, László Kőhidai, Eszter Lajkó
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 173, Iss , Pp 116293- (2024)
Pancreatic adenocarcinoma is one of the tumours with the worst prognosis, with a 5-year survival rate of 5–10%. Our aim was to find and optimise peptide-based drug conjugates with daunorubicin (Dau) as the cytotoxic antitumour agent. When conjugate
Externí odkaz:
https://doaj.org/article/294ba7a633b14376b6d253cbb79a4b69
Autor:
Gábor Mező, Jacopo Gomena, Ivan Ranđelović, Endre Levente Dókus, Krisztina Kiss, Lilla Pethő, Sabine Schuster, Balázs Vári, Diána Vári-Mező, Eszter Lajkó, Lívia Polgár, László Kőhidai, József Tóvári, Ildikó Szabó
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 3, p 1864 (2024)
Chemotherapy is still one of the main therapeutic approaches in cancer therapy. Nevertheless, its poor selectivity causes severe toxic side effects that, together with the development of drug resistance in tumor cells, results in a limitation for its
Externí odkaz:
https://doaj.org/article/550e5cbf283d46178a76a5594ee0a9e7
Autor:
Emilia Díaz López, Arturo Ríos Díaz, Oriana Vanegas Calderón, Eszter Lajkó, Alicia Ponte-Sucre, László Kőhidai
Publikováno v:
MethodsX, Vol 8, Iss , Pp 101223- (2021)
Chemotactic responses play a significant role during Leishmania (V.) braziliensis differentiation through its life cycle and during infection. The aim of this description has been to portray the modified “two-chamber capillary chemotaxis assay” a
Externí odkaz:
https://doaj.org/article/d3d3277f6b594734b020a3d21849a6a5
Autor:
Márton Kalabay, Zsófia Szász, Orsolya Láng, Eszter Lajkó, Éva Pállinger, Cintia Duró, Tamás Jernei, Antal Csámpai, Angéla Takács, László Kőhidai
Publikováno v:
Pharmaceuticals, Vol 15, Iss 3, p 314 (2022)
Tamoxifen is a long-known anti-tumor drug, which is the gold standard therapy in estrogen receptor (ER) positive breast cancer patients. According to previous studies, the conjugation of the original tamoxifen molecule with different functional group
Externí odkaz:
https://doaj.org/article/d056e206006744b4a549989a7e47e9a0
Autor:
Eszter Lajkó, Sarah Spring, Rózsa Hegedüs, Beáta Biri-Kovács, Sven Ingebrandt, Gábor Mező, László Kőhidai
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 14, Iss 1, Pp 2495-2509 (2018)
Background: Peptide hormone-based targeted tumor therapy is an approved strategy to selectively block the tumor growth and spreading. The gonadotropin-releasing hormone receptors (GnRH-R) overexpressed on different tumors (e.g., melanoma) could be ut
Externí odkaz:
https://doaj.org/article/8fbdc195542345c69ea27f0ff4c714bb
Autor:
Livia Polgár, Eszter Lajkó, Pál Soós, Orsolya Láng, Marilena Manea, Béla Merkely, Gábor Mező, László Kőhidai
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 14, Iss 1, Pp 1583-1594 (2018)
Background: Cardiomyopathy induced by the chemotherapeutic agents doxorubicin and daunorubicin is a major limiting factor for their application in cancer therapy. Chemotactic drug targeting potentially increases the tumor selectivity of drugs and dec
Externí odkaz:
https://doaj.org/article/52e2ab83540244008ec908e8c7eb8be5
Autor:
Angéla Takács, Zsófia Szász, Márton Kalabay, Péter Bárány, Antal Csámpai, Hargita Hegyesi, Orsolya Láng, Eszter Lajkó, László Kőhidai
Publikováno v:
Pharmaceuticals, Vol 14, Iss 8, p 820 (2021)
Combination antitumor treatments are essential parts of modern tumor therapy as—compared to monotherapies—(i) they are more effective; (ii) the dose of the compounds can be reduced; and (iii) therefore the side effects are improved. Our research
Externí odkaz:
https://doaj.org/article/aaf840b408d6461f9008a8261e8e190d
Autor:
Zsófia Kőhidai, Angéla Takács, Eszter Lajkó, Zoltán Géczi, Éva Pállinger, Orsolya Láng, László Kőhidai
Publikováno v:
Clinical Oral Investigations. 26:4559-4574
Objectives The gingiva epithelium accounts for a significant proportion of the surface around the tooth. An inflammatory reaction occurs in the presence of bacterial biofilm, adhesion is reduced, and the depth of the sulcus gingivalis increases. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6911fea45512a3564c97550e5ed5edc2
https://doi.org/10.1007/s00784-022-04422-z
https://doi.org/10.1007/s00784-022-04422-z