Global and cell type-specific immunological hallmarks of severe dengue progression identified via a systems immunology approach.

Autor: Ghita L; Division of Infectious Diseases and Geographic Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA., Yao Z; Division of Infectious Diseases and Geographic Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA., Xie Y; School of Clinical Medicine, UNSW Sydney, Sydney, New South Wales, Australia., Duran V; Division of Infectious Diseases and Geographic Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA.; Chan Zuckerberg Biohub-San Francisco, San Francisco, CA, USA., Cagirici HB; Division of Infectious Diseases and Geographic Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA., Samir J; School of Biomedical Sciences, UNSW Sydney, Sydney, New South Wales, Australia., Osman I; Division of Infectious Diseases and Geographic Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA., Rebellón-Sánchez DE; Clinical Research Center, Fundación Valle del Lili, Cali, Colombia., Agudelo-Rojas OL; Clinical Research Center, Fundación Valle del Lili, Cali, Colombia., Sanz AM; Clinical Research Center, Fundación Valle del Lili, Cali, Colombia., Sahoo MK; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA., Robinson ML; Division of Infectious Diseases and Geographic Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA., Gelvez-Ramirez RM; Centro de Atención y Diagnóstico de Enfermedades Infecciosas (CDI/Fundacion INFOVIDA), Bucaramanga, Colombia., Bueno N; Centro de Atención y Diagnóstico de Enfermedades Infecciosas (CDI/Fundacion INFOVIDA), Bucaramanga, Colombia., Luciani F; School of Biomedical Sciences, UNSW Sydney, Sydney, New South Wales, Australia., Pinsky BA; Division of Infectious Diseases and Geographic Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA.; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA., Montoya JG; Palo Alto Medical Foundation and Dr. Jack S. Remington Laboratory for Speciality Diagnostics, Palo Alto, CA, USA., Estupiñan-Cardenas MI; Centro de Atención y Diagnóstico de Enfermedades Infecciosas (CDI/Fundacion INFOVIDA), Bucaramanga, Colombia., Villar-Centeno LA; Centro de Atención y Diagnóstico de Enfermedades Infecciosas (CDI/Fundacion INFOVIDA), Bucaramanga, Colombia., Rojas-Garrido EM; Centro de Atención y Diagnóstico de Enfermedades Infecciosas (CDI/Fundacion INFOVIDA), Bucaramanga, Colombia., Rosso F; Clinical Research Center, Fundación Valle del Lili, Cali, Colombia.; Division of Infectious Diseases, Department of Internal Medicine, Fundación Valle del Lili, Cali, Colombia., Quake SR; Chan Zuckerberg Biohub-San Francisco, San Francisco, CA, USA.; Department of Bioengineering, Stanford University, Stanford, CA, USA.; Department of Applied Physics, Stanford University, Stanford, CA, USA., Zanini F; School of Clinical Medicine, UNSW Sydney, Sydney, New South Wales, Australia. fabio.zanini@unsw.edu.au.; Cellular Genomics Futures Institute, UNSW Sydney, Sydney, New South Wales, Australia. fabio.zanini@unsw.edu.au.; Evolution and Ecology Research Centre, UNSW Sydney, Sydney, New South Wales, Australia. fabio.zanini@unsw.edu.au., Einav S; Division of Infectious Diseases and Geographic Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA. seinav@stanford.edu.; Chan Zuckerberg Biohub-San Francisco, San Francisco, CA, USA. seinav@stanford.edu.; Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA, USA. seinav@stanford.edu.

Publikováno v: Nature immunology [Nat Immunol] 2023 Dec; Vol. 24 (12), pp. 2150-2163. Date of Electronic Publication: 2023 Oct 23.

An 8-gene machine learning model improves clinical prediction of severe dengue progression.

Autor: Liu YE; Institute for Immunity, Transplantation and Infection, School of Medicine, Stanford University, CA, Stanford, USA.; Cancer Biology Graduate Program, School of Medicine, Stanford University, CA, Stanford, USA.; Division of Infectious Diseases and Geographic Medicine, Department of Medicine, School of Medicine, Stanford University, CA, Stanford, USA., Saul S; Division of Infectious Diseases and Geographic Medicine, Department of Medicine, School of Medicine, Stanford University, CA, Stanford, USA., Rao AM; Institute for Immunity, Transplantation and Infection, School of Medicine, Stanford University, CA, Stanford, USA.; Immunology Graduate Program, School of Medicine, Stanford University, CA, Stanford, USA., Robinson ML; Division of Infectious Diseases and Geographic Medicine, Department of Medicine, School of Medicine, Stanford University, CA, Stanford, USA.; Department of Pathology, School of Medicine, Stanford University, CA, Stanford, USA., Agudelo Rojas OL; Clinical Research Center, Fundación Valle del Lili, Cali, Colombia., Sanz AM; Clinical Research Center, Fundación Valle del Lili, Cali, Colombia., Verghese M; Department of Pathology, School of Medicine, Stanford University, CA, Stanford, USA., Solis D; Department of Pathology, School of Medicine, Stanford University, CA, Stanford, USA., Sibai M; Department of Pathology, School of Medicine, Stanford University, CA, Stanford, USA., Huang CH; Department of Pathology, School of Medicine, Stanford University, CA, Stanford, USA., Sahoo MK; Department of Pathology, School of Medicine, Stanford University, CA, Stanford, USA., Gelvez RM; Centro de Atención y Diagnóstico de Enfermedades Infecciosas (CDI), Bucaramanga, Colombia., Bueno N; Centro de Atención y Diagnóstico de Enfermedades Infecciosas (CDI), Bucaramanga, Colombia., Estupiñan Cardenas MI; Centro de Atención y Diagnóstico de Enfermedades Infecciosas (CDI), Bucaramanga, Colombia., Villar Centeno LA; Centro de Atención y Diagnóstico de Enfermedades Infecciosas (CDI), Bucaramanga, Colombia., Rojas Garrido EM; Centro de Atención y Diagnóstico de Enfermedades Infecciosas (CDI), Bucaramanga, Colombia., Rosso F; Clinical Research Center, Fundación Valle del Lili, Cali, Colombia.; Division of Infectious Diseases, Department of Internal Medicine, Fundación Valle del Lili, Cali, Colombia., Donato M; Institute for Immunity, Transplantation and Infection, School of Medicine, Stanford University, CA, Stanford, USA.; Center for Biomedical Informatics Research, Department of Medicine, School of Medicine, Stanford University, CA, Stanford, USA., Pinsky BA; Division of Infectious Diseases and Geographic Medicine, Department of Medicine, School of Medicine, Stanford University, CA, Stanford, USA.; Department of Pathology, School of Medicine, Stanford University, CA, Stanford, USA., Einav S; Division of Infectious Diseases and Geographic Medicine, Department of Medicine, School of Medicine, Stanford University, CA, Stanford, USA.; Department of Microbiology and Immunology, School of Medicine, Stanford University, CA, Stanford, USA., Khatri P; Institute for Immunity, Transplantation and Infection, School of Medicine, Stanford University, CA, Stanford, USA. pkhatri@stanford.edu.; Center for Biomedical Informatics Research, Department of Medicine, School of Medicine, Stanford University, CA, Stanford, USA. pkhatri@stanford.edu.

Publikováno v: Genome medicine [Genome Med] 2022 Mar 29; Vol. 14 (1), pp. 33. Date of Electronic Publication: 2022 Mar 29.