Zobrazeno 1 - 10
of 118
pro vyhledávání: '"Estuardo Aguilar"'
Autor:
Marilin S. Koch, Mykola Zdioruk, Michal O. Nowicki, Alec M. Griffith, Estuardo Aguilar-Cordova, Laura K. Aguilar, Brian W. Guzik, Francesca Barone, Paul Peter Tak, Katharina Schregel, Michael S. Hoetker, James A. Lederer, E. Antonio Chiocca, Ghazaleh Tabatabai, Sean E. Lawler
Publikováno v:
Molecular Therapy: Oncolytics, Vol 26, Iss , Pp 275-288 (2022)
CAN-2409 is a replication-deficient adenovirus encoding herpes simplex virus (HSV) thymidine kinase (tk) currently in clinical trials for treatment of glioblastoma. The expression of tk in transduced cancer cells results in conversion of the pro-drug
Externí odkaz:
https://doaj.org/article/d1ff12c2b9db4d9895906f9830d6592e
Autor:
Francesca Barone, Paul P Tak, Sean Lawler, James A Lederer, Marilin S Koch, Mykola Zdioruk, Michal O Nowicki, Alec M Griffith, Estuardo Aguilar, Laura K Aguilar, Brian W Guzik, E Antonio Chiocca
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 1 (2022)
Externí odkaz:
https://doaj.org/article/06519b4a8e9e4394bfe536ab62aa59b5
Autor:
Francesca Barone, Hiroshi Nakashima, James Grant, David Reardon, Kai Wucherpfennig, Patrick Wen, Sean Lawler, Estuardo Aguilar-Cordova, Laura Aguilar, Brian Guzik, E Antonio Chiocca, Scott Rodig, Jessica Dwyer, Isaac Soloman, Daniel Triggs, Abigail Tianai Zhang, Yu Zeng, Jared Woods, Eudocia Quant Lee, Keith Ligon, William Pisano, Mario Suva, Sascha Marx, Simon Gritsch, Nathan Mathewson, David Krisky, Paul Tak
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/3d30837249f94c8eaaf1fa895558ac69
Autor:
Sean Lawler, Marilin Koch, Mikolay Zdioruk, Estuardo Aguilar-Cordova, Laura Aguilar, Brian Guzik, Ghazaleh Tabatabai, Michal Nowicki, E Antonio Chiocca
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/ac9330ce6bec4ab7901ec8fac3c708b7
Human aldehyde reductase promoter allows simultaneous expression of two genes in opposite directions
Autor:
Oleg A. Barski, Fernando Siller-Lopez, Kurt M. Bohren, Kenneth H. Gabbay, Estuardo Aguilar-Cordova
Publikováno v:
BioTechniques, Vol 36, Iss 3, Pp 382-388 (2004)
Externí odkaz:
https://doaj.org/article/67a23abbd9574cb884c8bc9250a9e955
Autor:
Lawrence A. Shirley, Laura K. Aguilar, Estuardo Aguilar-Cordova, Mark Bloomston, Jon P. Walker
Publikováno v:
Gastroenterology Research and Practice, Vol 2013 (2013)
Pancreatic adenocarcinoma is an aggressive disease that has poor outcomes despite maximal traditional therapies. Thus, treatment of this cancer demands innovative strategies to be used in addition to standing therapies in order to provide new avenues
Externí odkaz:
https://doaj.org/article/0123f03e49ba4e228f2f224ed1c19179
Publikováno v:
Viral Genome Methods ISBN: 9781003420163
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c83b83aac1766d7838f9cfebc099a86
https://doi.org/10.1201/9781003420163-6
https://doi.org/10.1201/9781003420163-6
Autor:
Mitchell G. Bryski, Jason Stadanlick, Brian W. Guzik, Patrick Woodruff, Lydia G. Frenzel-Sulyok, Edmund K. Moon, Laura K. Aguilar, Charuhas Deshpande, Estuardo Aguilar-Cordova, Steven M. Albelda, Evgeniy Eruslanov, Andrea G. Manzanera, Corey J. Langer, Jarrod D. Predina, Sunil Singhal, Marina Martinez, Andrew R. Haas, Christopher Corbett, Shaun O'Brien
Publikováno v:
Molecular Therapy
Gene-mediated cytotoxic immunotherapy (GMCI) is an immuno-oncology approach involving local delivery of a replication-deficient adenovirus expressing herpes simplex thymidine kinase (AdV-tk) followed by anti-herpetic prodrug activation that promotes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04a9e6c798bf28eac1e5e6c327b25bfd
http://europepmc.org/articles/PMC7854297
http://europepmc.org/articles/PMC7854297
Autor:
Marilin S Koch, Mykola Zdioruk, Michal O Nowicki, Alec M Griffith, Estuardo Aguilar, Laura K Aguilar, Brian W Guzik, Francesca Barone, Paul P Tak, Ghazaleh Tabatabai, James A Lederer, E Antonio Chiocca, Sean Lawler
Publikováno v:
Journal for Immunotherapy of Cancer
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 1 (2022)
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 1 (2022)
BackgroundIntratumoral viral oncolytic immunotherapy is a promising new approach for the treatment of a variety of solid cancers. CAN-2409 is a replication-deficient adenovirus that delivers herpes simplex virus thymidine kinase to cancer cells, resu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82b8be09b80beec58beda1af9d511f57
https://pubmed.ncbi.nlm.nih.gov/35017150
https://pubmed.ncbi.nlm.nih.gov/35017150
Autor:
E Antonio Chiocca, Hiroshi Nakashima, Xiaokui Mo, Isaac Solomon, Alexander Ling, Jared Woods, Joshua Bernstock, Genaro Villa, Raziye Piranlioglu, Ana Montalvo Landivar, Nafisa Masud, Daniel Triggs, James Grant, Patrick Y Wen, Eudocia Lee, Lakshmi Nayak, Ugonma Chukwueke, Tracy Batchelor, David Krisky, Estuardo Aguilar-Cordova, Laura K Aguilar, Soledad Fernandez, Christopher Matheny, Andrea Manzanera, Francesca Barone, Paul Peter Tak, Keith Ligon, David A Reardon
Publikováno v:
Neuro-Oncology. 24:vii61-vii61
BACKGROUND CAN-3110 (rQNestin34.5v2) is an HSV-1 oncolytic viral immunotherapy with one copy of the inflammatory ICP34.5 gene under transcriptional control of the Nestin glioma-specific promoter. We completed a phase 1 sequential dose-escalation tria
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19461b0ab541fea08c319be4c93a0c22
https://doi.org/10.1093/neuonc/noac209.241
https://doi.org/10.1093/neuonc/noac209.241