Genome-wide interaction analysis of menopausal hormone therapy use and breast cancer risk among 62,370 women

Autor: Kathryn J. Ruddy, Qin Wang, Joe Dennis, Stacey J. Winham, Janet E. Olson, Thomas U. Ahearn, Rachel A. Murphy, Wing-Yee Lo, David J. Hunter, Manjeet K. Bolla, Douglas F. Easton, Derrick G. Lee, Marike Gabrielson, Gareth D. Evans, Nick Orr, Reiner Hoppe, Minouk J. Schoemaker, Paul L. Auer, Michael Lush, Andrew F. Olshan, Kristan J. Aronson, Ross L. Prentice, Argyrios Ziogas, Martha S. Linet, Melissa C. Southey, Robert J. MacInnis, Michael Jones, Nicole L. Larson, Elke M van Veen, Anthony Howell, Alison M. Dunning, Christopher A. Haiman, Peter Kraft, William G. Newman, Loic Le Marchand, Lauren R. Teras, Jenny Chang-Claude, Mikael Eriksson, Irene L. Andrulis, Graham G. Giles, Heiko Becher, Montserrat Garcia-Closas, Thomas Brüning, A. Heather Eliassen, Pascal Guénel, Cari M. Kitahara, Pooja Middha Kapoor, Hoda Anton-Culver, Niclas Håkansson, Emilie Cordina-Duverger, Xiaoliang Wang, Stephen J. Chanock, Christopher J. Scott, Anthony J. Swerdlow, Ute Krüger, Sara Lindström, Roger L. Milne, Alpa V. Patel, Kristen Brantley, Annelie Augustinsson, Rulla M. Tamimi, Lynne R. Wilkens, Celine M. Vachon, Alicja Wolk, Håkan Olsson, Fergus J. Couch, Ute Hamann, Philippe Wagner, Kamila Czene, Audrey Y. Jung, Rudolf Kaaks, Claire Mulot, Laure Dossus, Angela Brooks-Wilson, Kyriaki Michailidou, Per Hall, Jonine D. Figueroa, Thérèse Truong, Charles M. Perou, Melissa A. Troester

Publikováno v: Wang, X, Kapoor, P M, Auer, P L, Dennis, J, Dunning, A M, Wang, Q, Lush, M, Michailidou, K, Bolla, M K, Aronson, K J, Murphy, R A, Brooks-wilson, A, Lee, D G, Cordina-duverger, E, Guénel, P, Truong, T, Mulot, C, Teras, L R, Patel, A V, Dossus, L, Kaaks, R, Hoppe, R, Lo, W, Brüning, T, Hamann, U, Czene, K, Gabrielson, M, Hall, P, Eriksson, M, Jung, A, Becher, H, Couch, F J, Larson, N L, Olson, J E, Ruddy, K J, Giles, G G, Macinnis, R J, Southey, M C, Le Marchand, L, Wilkens, L R, Haiman, C A, Olsson, H, Augustinsson, A, Krüger, U, Wagner, P, Scott, C, Winham, S J, Vachon, C M, Perou, C M, Olshan, A F, Troester, M A, Hunter, D J, Eliassen, H A, Tamimi, R M, Brantley, K, Andrulis, I L, Figueroa, J, Chanock, S J, Ahearn, T U, García-closas, M, Evans, G D, Newman, W G, Van Veen, E M, Howell, A, Wolk, A, Håkansson, N, Anton-culver, H, Ziogas, A, Jones, M E, Orr, N, Schoemaker, M J, Swerdlow, A J, Kitahara, C M, Linet, M, Prentice, R L, Easton, D F, Milne, R L, Kraft, P, Chang-claude, J & Lindström, S 2022, ' Genome-wide interaction analysis of menopausal hormone therapy use and breast cancer risk among 62,370 women ', Scientific Reports, vol. 12, no. 1, 6199 . https://doi.org/10.1038/s41598-022-10121-2
Wang, X, Kapoor, P M, Auer, P L, Dennis, J, Dunning, A M, Wang, Q, Lush, M, Michailidou, K, Bolla, M K, Aronson, K J, Murphy, R A, Brooks-Wilson, A, Lee, D G, Cordina-Duverger, E, Guénel, P, Truong, T, Mulot, C, Teras, L R, Patel, A V, Dossus, L, Kaaks, R, Hoppe, R, Lo, W-Y, Brüning, T, Hamann, U, Czene, K, Gabrielson, M, Hall, P, Eriksson, M, Jung, A, Becher, H, Couch, F J, Larson, N L, Olson, J E, Ruddy, K J, Giles, G G, MacInnis, R J, Southey, M C, Le Marchand, L, Wilkens, L R, Haiman, C A, Olsson, H, Augustinsson, A, Krüger, U, Wagner, P, Scott, C, Winham, S J, Vachon, C M, Perou, C M, Olshan, A F, Troester, M A, Hunter, D J, Eliassen, H A, Tamimi, R M, Brantley, K, Andrulis, I L, Figueroa, J, Chanock, S J, Ahearn, T U, García-Closas, M, Evans, G D, Newman, W G, van Veen, E M, Howell, A, Wolk, A, Håkansson, N, Anton-Culver, H, Ziogas, A, Jones, M E, Orr, N, Schoemaker, M J, Swerdlow, A J, Kitahara, C M, Linet, M, Prentice, R L, Easton, D F, Milne, R L, Kraft, P, Chang-Claude, J & Lindström, S 2022, ' Genome-wide interaction analysis of menopausal hormone therapy use and breast cancer risk among 62,370 women ', Scientific Reports, vol. 12, 6199 . https://doi.org/10.1038/s41598-022-10121-2

Background: Use of menopausal hormone therapy (MHT) is associated with increased risk for breast cancer. However, the relevant mechanisms and its interaction with genetic variants are not fully understood. Methods: We conducted a genome-wide interact

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::097ea0222331bfb442ea490c2ed9cd1e

Overcoming Women’s Lifelong Hormonal Rollercoaster: A Turning Point for Cardiovascular Prevention

Autor: M. Julia Machline-Carrion

Publikováno v: Arquivos Brasileiros de Cardiologia, Volume: 118, Issue: 5, Pages: 914-915, Published: 13 MAY 2022

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fa477b728e54c516ccaa27aed376fab
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2022000500914&lng=en&tlng=en

Endometriosis after menopause: physiopathology and management of an uncommon condition

Autor: Jean-Marie Wenger, Patrick Petignat, Gaitzsch H, Isabelle Streuli

Publikováno v: Climacteric, Vol. 20, No 2 (2017) pp. 138-143

Endometriosis is a hormone-dependent inflammatory disease that is usually characterized by infertility and pain symptoms. This disease mainly occurs during the reproductive years and is rarely diagnosed after menopause. We discuss the physiopathology

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd31da6e93ef1b510d70405a68fc0fa0
https://doi.org/10.1080/13697137.2017.1284781

Global burden of cancer attributable to high body-mass index in 2012: a population-based study

Autor: Gretchen A Stevens, Andrew G Renehan, Graham Byrnes, J. Jaime Miranda, Isabelle Soerjomataram, Majid Ezzati, Jacques Ferlay, Melina Arnold, David Forman, Nirmala Pandeya, Rajesh Dikshit, Isabelle Romieu

Publikováno v: Arnold, M, Pandeya, N, Byrnes, G, Renehan, A G, Stevens, G A, Ezzati, M, Ferlay, J, Miranda, J J, Romieu, I, Dikshit, R, Forman, D & Soerjomataram, I 2014, ' Global burden of cancer attributable to high body-mass index in 2012: a population-based study ', Lancet Oncol, vol. 16, no. 1, pp. 36-46 . https://doi.org/10.1016/s1470-2045(14)71123-4
Arnold, M, Pandeya, N, Byrnes, G, Renehan, A G, Stevens, G A, Ezzati, M, Ferlay, J, Miranda, J J, Romieu, I, Dikshit, R, Forman, D & Soerjomataram, I 2015, ' Global burden of cancer attributable to high body-mass index in 2012: a population-based study ', Lancet Oncol, vol. 16, no. 1, pp. 36-46 . https://doi.org/10.1016/s1470-2045(14)71123-4

Summary Background High body-mass index (BMI; defined as 25 kg/m 2 or greater) is associated with increased risk of cancer. To inform public health policy and future research, we estimated the global burden of cancer attributable to high BMI in 2012.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf86d6da7ec47e50e65f4fe90c63ebf7
https://doi.org/10.1016/s1470-2045(14)71123-4

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