Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Esti Singer"'
Publikováno v:
eLife, Vol 6 (2017)
Fumarase is distributed between two compartments of the eukaryotic cell. The enzyme catalyses the reversible conversion of fumaric to L-malic acid in mitochondria as part of the tricarboxylic acid (TCA) cycle, and in the cytosol/nucleus as part of th
Externí odkaz:
https://doaj.org/article/25c6c4a7b2d241c0a3bf24e62ede109c
Autor:
Ohad Yogev, Orli Yogev, Esti Singer, Eitan Shaulian, Michal Goldberg, Thomas D Fox, Ophry Pines
Publikováno v:
PLoS Biology, Vol 8, Iss 3, p e1000328 (2010)
In eukaryotes, fumarase (FH in human) is a well-known tricarboxylic-acid-cycle enzyme in the mitochondrial matrix. However, conserved from yeast to humans is a cytosolic isoenzyme of fumarase whose function in this compartment remains obscure. A few
Externí odkaz:
https://doaj.org/article/4d8f2d8666b24938b2448c19af354e30
Publikováno v:
Proc Natl Acad Sci U S A
Class-II fumarases (fumarate hydratase, FH) are dual-targeted enzymes occurring in the mitochondria and cytosol of all eukaryotes. They are essential components in the DNA damage response (DDR) and, more specifically, protect cells from DNA double-st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e5d74f9558ed8e6b26e2cae8fcacb4aa
https://pubmed.ncbi.nlm.nih.gov/34083440
https://pubmed.ncbi.nlm.nih.gov/34083440
Publikováno v:
Proceedings of the National Academy of Sciences. 118
Class-II fumarases (fumarate hydratase, FH) are dual-targeted enzymes occurring in the mitochondria and cytosol of all eukaryotes. They are essential components in the DNA damage response (DDR) and, more specifically, protect cells from DNA double-st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb281728706f3d197929f6794b752f6c
https://doi.org/10.1073/pnas.2026595118
https://doi.org/10.1073/pnas.2026595118
Class-II fumarases (Fumarate Hydratase, FH) are dual targeted enzymes, occurring in the mitochondria and cytosol of all eukaryotes. They are essential components in the DNA damage response (DDR) and more specifically, protecting cells from DNA double
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::acf2c00693f0599cdf22514796cbf088
https://doi.org/10.1101/2020.08.04.232652
https://doi.org/10.1101/2020.08.04.232652
Publikováno v:
eLife, Vol 6 (2017)
eLife
eLife
Fumarase is distributed between two compartments of the eukaryotic cell. The enzyme catalyses the reversible conversion of fumaric to L-malic acid in mitochondria as part of the tricarboxylic acid (TCA) cycle, and in the cytosol/nucleus as part of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::386705e69705f90d6d4953e5b04c5aa4
https://doi.org/10.7554/elife.30927
https://doi.org/10.7554/elife.30927