Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Esther Trueblood"'
Autor:
Elizabeth Gray, Shyra Gardai, Kelly Hensley, Sean Allred, Esther Trueblood, John Gosink, Katie Snead, Michelle Ulrich, Alyson Smith, Angela Epp, Disha Sahetya, Julie Hahn, Jane Haass, Sasha Lucas, Rogely Boyce, Piper Treuting, Chris Frantz, Jason Schrum, Natalya Nazarenko
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/69edefe076c94b3782fb3ef57afa2c8f
Autor:
Elizabeth Gray, Jeffrey Harris, Celine Jacquemont, Kelly Hensley, Sean Allred, Esther Trueblood, John Gosink, Robert Thurman, Kaleb Smith, Mark Bieda, Jason Gow, Lauren Brady, Ibrahima Soumaoro, Shweta Jain, Leonardo Nicacio
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/63930837eee04cd09b68aa1d96d40ddb
Autor:
Kent Miner, Katja Labitzke, Benxian Liu, Paul Wang, Kathryn Henckels, Kevin Gaida, Robin Elliott, Jian Jeffrey Chen, Longbin Liu, Anh Leith, Esther Trueblood, Kelly Hensley, Xing-Zhong Xia, Oliver Homann, Brian Bennett, Mike Fiorino, John Whoriskey, Gang Yu, Sabine Escobar, Min Wong, Teresa L. Born, Alison Budelsky, Mike Comeau, Dirk Smith, Jonathan Phillips, James A. Johnston, Joseph G. McGivern, Kerstin Weikl, David Powers, Karl Kunzelmann, Deanna Mohn, Andreas Hochheimer, John K. Sullivan
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
There is an unmet need in severe asthma where approximately 40% of patients exhibit poor β-agonist responsiveness, suffer daily symptoms and show frequent exacerbations. Antagonists of the Ca2+-activated Cl− channel, TMEM16A, offers a new mechanis
Externí odkaz:
https://doaj.org/article/41d8cbf66f0741758aee1902a2f9ab21
Autor:
Christopher Carosino, Devra Olson, Katie Snead, Anthony Lee, Lauren Farr, Amit Garg, Christine O'Day, Esther Trueblood, Jennifer Wright, Mark Bieda, Charles Caldwell, Kelly Hensley, Sean Allred, Bernard Liu, Masashi Shimazaki, Sharsti Sandall
Publikováno v:
Cancer Research. 82:1140-1140
Enfortumab vedotin (EV) is a monomethyl auristatin E (MMAE) containing antibody-drug conjugate directed to Nectin-4, which is highly expressed in bladder cancers. Preclinically, EV has demonstrated tumor cell-killing by direct cytotoxicity, bystander
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53e0c6bc1ec8b3a440f18b9a038adefc
https://doi.org/10.1158/1538-7445.am2022-1140
https://doi.org/10.1158/1538-7445.am2022-1140
Autor:
Sarah Anderson, Nanna Hansen, Robert Lawrence, Aroon T. Chande, David Ortiz, Christopher Carosino, Esther Trueblood, Nicole Stevens, Kerry Klussman, Angela Epp, Bill Arthur, Shyra Gardai, Hector Rincon
Publikováno v:
Cancer Research. 82:1766-1766
Antibody-drug conjugates (ADC) leverage the specificity of antibodies to direct the delivery of potent cytotoxic agents to cancer cells. To fully leverage this specificity, targets with significant differential tumor versus normal tissue expression a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ebfa19a3ff29c951057c347fb6d1691
https://doi.org/10.1158/1538-7445.am2022-1766
https://doi.org/10.1158/1538-7445.am2022-1766
Autor:
Kaleb Smith, Celine Jacquemont, Jeffrey R. Harris, Robert Thurman, Leonardo Viana Nicacio, John Gosink, Shyra Gardai, Esther Trueblood, Lauren Brady, I. Soumaoro, Jason Gow, Kelly Hensley, Mark Bieda, Shweta Jain, Sean Allred, Elizabeth Gray
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Background Tisotumab vedotin (TV) is an investigational antibody-drug conjugate composed of a tissue factor (TF)-directed human monoclonal antibody covalently linked to the microtubule-disrupting agent monomethyl auristatin E (MMAE) via a protease-cl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e2e3ba62cbbdbb65738e05828a9df3d
https://doi.org/10.1136/jitc-2020-sitc2020.0617
https://doi.org/10.1136/jitc-2020-sitc2020.0617
Autor:
Maureen Ryan, Lori Westendorf, Michael W. Schmitt, Mechthild Jonas, Esther Trueblood, Roma C. Yumul, Christopher E. Franz, Robert P. Lyon
Publikováno v:
Cancer Research. 80:2906-2906
The integrins are a large family of cell surface receptors with diverse roles in cellular adhesion, motility, and cytokinesis. Functional integrins exist as heterodimers consisting of single alpha and beta chains. Within this family, integrin beta-6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d30da5dbe39d0cf7e7a64f924973d33
https://doi.org/10.1158/1538-7445.am2020-2906
https://doi.org/10.1158/1538-7445.am2020-2906
Autor:
Sharsti L. Sandall, Marsha Mason, Devra Olson, Rebecca Mazahreh, Tom Pires, Disha Sahetya, Lori Westendorf, Chris Leiske, Brian Schimpf, Liem Nguyen, Madhu Katepalli, Esther Trueblood, Christopher Hale, Albina Nesterova, Jason Wall, Timothy S. Lewis
Publikováno v:
Cancer Research. 79:2688-2688
Melanotransferrin (CD228/MFI2/MELTF) is a cell-surfaced glycosylphosphatidylinoitol (GPI)-anchored glycoprotein that belongs to the transferrin family of iron-binding proteins. CD228 was first described as an oncofetal protein highly expressed on mal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f29cc634212cee568bf1d7aab827eae0
https://doi.org/10.1158/1538-7445.am2019-2688
https://doi.org/10.1158/1538-7445.am2019-2688
Autor:
Noah B. Pefaur, Esther Trueblood, Gregory N. Dietsch, Suzanne Kanaly, Russell J. Eyre, Karen M. Poole, William D. Welch, Chris R. Dipalma, William D. Kerns, Tuan Q. Pham
Publikováno v:
Toxicologic Pathology. 34:39-51
The primary toxicity associated with repeated oral administration of the PDE4 inhibitor IC542 to the rat is an inflammatory response leading to tissue damage primarily in the gastrointestinal tract and mesentery. Although necrotizing vasculitis is fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dba2da80877ea4334873b81a292fbe33
https://doi.org/10.1080/01926230500385549
https://doi.org/10.1080/01926230500385549
Autor:
Esther Trueblood, Tim Axtelle, intro by Rainer Storb, Brenda M. Sandmaier, Kelly Hensley, Anne Stucki, Marykay Ligocki, Linda Mackeen, Joel S. Hayflick
Publikováno v:
Experimental Hematology. 28:59-60
Intercellular Adhesion Molecule (ICAM)-3 is a hematopoietic specific counter receptor for a subset of beta 2 integrins. Previously, we observed that specific murine monoclonal antibody (mAb) engagement of ICAM-3 led to apoptosis of a bone marrow-deri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::37a41608c9a29b6e0690d3f9bf6a01ce
https://doi.org/10.1016/s0301-472x(00)00274-5
https://doi.org/10.1016/s0301-472x(00)00274-5