Condensin positioning at telomeres by shelterin proteins drives sister-telomere disjunction in anaphase

Autor: Léonard Colin, Celine Reyes, Julien Berthezene, Laetitia Maestroni, Laurent Modolo, Esther Toselli, Nicolas Chanard, Stephane Schaak, Olivier Cuvier, Yannick Gachet, Stephane Coulon, Pascal Bernard, Sylvie Tournier

Publikováno v: eLife, Vol 12 (2023)

The localization of condensin along chromosomes is crucial for their accurate segregation in anaphase. Condensin is enriched at telomeres but how and for what purpose had remained elusive. Here, we show that fission yeast condensin accumulates at tel

Externí odkaz: https://doaj.org/article/ae1632c8ec9d4cbe92ca22befe09a455

Fatty acid desaturation links germ cell loss to longevity through NHR-80/HNF4 in C. elegans.

Autor: Jérôme Goudeau, Stéphanie Bellemin, Esther Toselli-Mollereau, Mehrnaz Shamalnasab, Yiqun Chen, Hugo Aguilaniu

Publikováno v: PLoS Biology, Vol 9, Iss 3, p e1000599 (2011)

Preventing germline stem cell proliferation extends lifespan in nematodes and flies. So far, studies on germline-longevity signaling have focused on daf-16/FOXO and daf-12/VDR. Here, we report on NHR-80/HNF4, a nuclear receptor that specifically medi

Externí odkaz: https://doaj.org/article/b0f2ada3d97843a88d1b012d8b112c2a

Condensin controls cellular RNA levels through the accurate segregation of chromosomes instead of directly regulating transcription

Autor: Esther Toselli, Claire Burny, Laurent Modolo, Xi-Ming Sun, Christian H. Haering, Samuel Marguerat, Pascal Bernard, Xavier Robellet, Lars M. Steinmetz, Clémence Hocquet, Sandra Clauder-Münster, Sara Cuylen-Haering

Publikováno v: eLife
eLife, eLife Sciences Publication, 2018, 7, ⟨10.7554/eLife.38517⟩
eLife, 2018, 7, ⟨10.7554/eLife.38517⟩
eLife, Vol 7 (2018)

Condensins are genome organisers that shape chromosomes and promote their accurate transmission. Several studies have also implicated condensins in gene expression, although the mechanisms have remained enigmatic. Here, we report on the role of conde

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4284f9a97af2e96359b7465b1fcb698
https://hal.archives-ouvertes.fr/hal-02347214

Nucleosome eviction in mitosis assists condensin loading and chromosome condensation

Autor: Xavier Robellet, Pascal Bernard, Esther Toselli-Mollereau, Christian H. Haering, Emilie Chautard, Lydia Fauque, Carlo Klein, Léo Mouillard, Lia N'Guyen, Sébastien Lemaire, Pénélope Legros, Clémence Hocquet, Christoph Schiklenk, Didier Auboeuf

Publikováno v: EMBO Journal
EMBO Journal, EMBO Press, 2016, 35 (14), pp.1565-1581. ⟨10.15252/embj.201592849⟩
EMBO Journal, 2016, 35 (14), pp.1565-1581. ⟨10.15252/embj.201592849⟩

Condensins associate with DNA and shape mitotic chromosomes. Condensins are enriched nearby highly expressed genes during mitosis, but how this binding is achieved and what features associated with transcription attract condensins remain unclear. Her

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::305c2071295750b6a7326f74ce943e95
https://europepmc.org/articles/PMC4946138/

Fatty Acid Desaturation Links Germ Cell Loss to Longevity Through NHR-80/HNF4 in C. elegans

Autor: Hugo Aguilaniu, Mehrnaz Shamalnasab, Jérôme Goudeau, Esther Toselli-Mollereau, Stéphanie Bellemin, Yiqun Chen

Publikováno v: PLoS Biology
PLoS Biology, 2011, 9 (3), pp.e1000599
PLoS Biology, Vol 9, Iss 3, p e1000599 (2011)

Background Preventing germline stem cell proliferation extends lifespan in nematodes and flies. So far, studies on germline-longevity signaling have focused on daf-16/FOXO and daf-12/VDR. Here, we report on NHR-80/HNF4, a nuclear receptor that specif

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f661101b3bdfd8397f08e1c88694dae5
https://hal-ens-lyon.archives-ouvertes.fr/ensl-00809202