MPX-004 and MPX-007: New Pharmacological Tools to Study the Physiology of NMDA Receptors Containing the GluN2A Subunit.

Autor: Robert A Volkmann, Christopher M Fanger, David R Anderson, Venkata Ramana Sirivolu, Kathy Paschetto, Earl Gordon, Caterina Virginio, Melanie Gleyzes, Bruno Buisson, Esther Steidl, Susanna B Mierau, Michela Fagiolini, Frank S Menniti

Publikováno v: PLoS ONE, Vol 11, Iss 2, p e0148129 (2016)

GluN2A is the most abundant of the GluN2 NMDA receptor subunits in the mammalian CNS. Physiological and genetic evidence implicate GluN2A-containing receptors in susceptibility to autism, schizophrenia, childhood epilepsy and neurodevelopmental disor

Externí odkaz: https://doaj.org/article/2735bce216d245b2951e2be95a93cd11

Neuroservice proconvulsive (NS-PC) set: A new platform of electrophysiology-based assays to determine the proconvulsive potential of lead compounds

Autor: Fabien Maddalena, Esther Steidl, Bruno Buisson, Dominique Debanne, Melanie Gleyzes

Publikováno v: Journal of Pharmacological and Toxicological Methods
Journal of Pharmacological and Toxicological Methods, Elsevier, 2019, ⟨10.1016/j.vascn.2019.106587⟩
Journal of Pharmacological and Toxicological Methods, 2019, ⟨10.1016/j.vascn.2019.106587⟩

Introduction Failures in drug development often result from the emergence of unexpected adverse drug reactions. It is clear that adverse drug reactions, including seizure liability, should be assessed earlier. The goal of the present work was to deve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f69002d82da232f0f5fb8391a92b181a
https://hal-amu.archives-ouvertes.fr/hal-02363593

MPX-004 and MPX-007: New Pharmacological Tools to Study the Physiology of NMDA Receptors Containing the GluN2A Subunit

Autor: Frank S. Menniti, Esther Steidl, Earl Gordon, Michela Fagiolini, Bruno Buisson, Caterina Virginio, Kathy Paschetto, Volkmann Robert A, Melanie Gleyzes, Christopher Fanger, David E. Anderson, Susanna B. Mierau, Venkata Ramana Sirivolu

Publikováno v: PLoS ONE, Vol 11, Iss 2, p e0148129 (2016)
PLoS ONE

GluN2A is the most abundant of the GluN2 NMDA receptor subunits in the mammalian CNS. Physiological and genetic evidence implicate GluN2A-containing receptors in susceptibility to autism, schizophrenia, childhood epilepsy and neurodevelopmental disor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::168819f797ff48a60c2061679f0984eb
http://europepmc.org/articles/PMC4734667?pdf=render

Myotonic dystrophy CTG expansion affects synaptic vesicle proteins, neurotransmission and mouse behaviour. : Synaptic dysfunction in myotonic dystrophy

Autor: Takashi Kimura, Bulmaro Cisneros, Esther Steidl, F. Trovero, Elodie Marciniak, Arnold Munnich, Yasuhiro Suzuki, Luc Buée, Geneviève Gourdon, Bruno Buisson, Oscar Hernández-Hernández, Hélène Obriot, Friedrich Metzger, Stefanie Saenger, Maurice S. Swanson, Tohru Matsuura, Konstantinos Charizanis, Jean-Charles Bizot, Mário Gomes-Pereira, Guillaume Bassez, Sabrina Luilier, Caroline Chevarin, Géraldine Sicot, Sandrine Humez, Michel Hamon, Kuang-Yung Lee, Nicolas Sergeant, Aline Huguet, Céline Guiraud-Dogan, Annie Nicole, Lucile Revillod

Publikováno v: Brain-A Journal of Neurology
Brain-A Journal of Neurology, 2013, 136 (Pt 3), pp.957-70. ⟨10.1093/brain/aws367⟩
Brain-A Journal of Neurology, Oxford University Press (OUP), 2013, 136 (Pt 3), pp.957-70. ⟨10.1093/brain/aws367⟩
Brain-A Journal of Neurology, Oxford University Press (OUP), 2013, 136 (Pt 3), pp.957-70. 〈10.1093/brain/aws367〉

International audience; Myotonic dystrophy type 1 is a complex multisystemic inherited disorder, which displays multiple debilitating neurological manifestations. Despite recent progress in the understanding of the molecular pathogenesis of myotonic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d4d31ff5c6ae571d4b36eeb50c2169b
https://www.hal.inserm.fr/inserm-00795195/document