Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Esther Siegfried"'
Autor:
Hiroshi Nakato, Melanie Humphrey, Lynn Stam, Sara K. Olson, Tracy A. Futch, Michael Archer, Scott B. Selleck, Manabu Tsuda, Keisuke Kamimura, Vesna Kaluza, William D. Staatz, Bethany Fox, Esther Siegfried
Publikováno v:
Nature. 400:276-280
Wingless (Wg) is a member of the Wnt family of growth factors, secreted proteins that control proliferation and differentiation during development. Studies in Drosophila have shown that responses to Wg require cell-surface heparan sulphate, a glycosa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::81c4ef91b3e0578ef4c5503596917098
https://doi.org/10.1038/22336
https://doi.org/10.1038/22336
Publikováno v:
Developmental Biology. 197(2):218-233
The extracellular signals encoded by the Wnt family of genes regulate growth and differentiation in several developmental processes in both vertebrates and invertebrates. Genetic studies of the signaling pathway of the Drosophila Wnt homologue, Wingl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b76916a02cf95b75722766f7af7797be
Publikováno v:
Cell. 71:1167-1179
Summary Intrasegmental patterning in the Drosophila embryo is regulated by cell-cell communication. One of the signaling pathways that operates to specify positional information throughout the segment is mediated by the wingless (wg) protein, which i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71172114f7709db5a452912f69689bb0
https://doi.org/10.1016/s0092-8674(05)80065-0
https://doi.org/10.1016/s0092-8674(05)80065-0
Publikováno v:
Nature. 345:825-829
THE metameric pattern of the Drosophila embryo is regulated by a combination of maternal and zygotic genes. The segment-polarity class of genes are required for the correct patterning within each segmental unit. Mutations in any one of these genes re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c34b8d3d3e7a2bd45ac9196eba89bfee
https://doi.org/10.1038/345825a0
https://doi.org/10.1038/345825a0
Publikováno v:
Journal of Molecular Biology. 211:751-761
We report here the analysis of the sequence requirements for the heat-induced expression of the Drosophila melanogaster hsp26 gene using germline transformation. Heat-induced expression is augmented fivefold by a homopurine/homopyrimidine region from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82048c8cec0c5f815640aded9147da00
https://doi.org/10.1016/0022-2836(90)90075-w
https://doi.org/10.1016/0022-2836(90)90075-w
Retroposition is increasingly recognized as an important mechanism for the acquisition of new genes. We show that a glycogen synthase kinase-3 gene, shaggy (sgg), retroposed at least 50 MYA in the Drosophila genus to generate a new gene, mojoless (mj
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b98225d492238935982c726016a03324
https://europepmc.org/articles/PMC2292417/
https://europepmc.org/articles/PMC2292417/
Autor:
Esther Siegfried
Publisher Summary This chapter highlights some of the functions of wingless protein (Wg) in cell fate determination. Wg has a role in patterning a variety of embryonic tissues; however, the best studied developmental role for Wg is in embryonic segme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de82de876a5fe3ae59660eb3cbc67ba9
https://doi.org/10.1016/b978-012505255-9/50018-3
https://doi.org/10.1016/b978-012505255-9/50018-3
Autor:
Norbert Perrimon, Esther Siegfried
Publikováno v:
BioEssays : news and reviews in molecular, cellular and developmental biology. 16(6)
The link between oncogenesis and normal development is well illustrated by the study of the Wnt family of proteins. The first Wnt gene (int-1) was identified over a decade ago as a proto-oncogene, activated in response to proviral insertion of a mous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f06f83bfb2f9c43ebb9de359a09705d
https://pubmed.ncbi.nlm.nih.gov/8080429
https://pubmed.ncbi.nlm.nih.gov/8080429
Publikováno v:
Nature. 367(6458)
THE determination of specific cell fates and polarity within each segmental unit of the Drosophila embryo involves the products of the segment polarity genes1. One of these, wingless (wg), encodes a secreted protein2,3 that is homologous to the mamma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bcdc94cb9fbff5fd6f73a5e972b62aa
https://pubmed.ncbi.nlm.nih.gov/8107779
https://pubmed.ncbi.nlm.nih.gov/8107779
Publikováno v:
Trends in genetics : TIG. 6(11)
The study of serine/threonine kinases in Drosophila is coming of age. Recently several kinases have been identified and their role in cell determination has been established. This review discusses these recent findings and describes the potential for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bed5a9fbada2076c558614926beed072
https://pubmed.ncbi.nlm.nih.gov/2150900
https://pubmed.ncbi.nlm.nih.gov/2150900