Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Esther Sanchez de Leon"'
Autor:
Peter J. Cook, Rozario Thomas, Ram Kannan, Esther Sanchez de Leon, Alexander Drilon, Marc K. Rosenblum, Maurizio Scaltriti, Robert Benezra, Andrea Ventura
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
The use of mouse models has been an invaluable resource in cancer research but their generation is lengthy and costly. Here the authors describe an approach to generate engineered mouse models carrying specific gene fusions and, as a proof of princip
Externí odkaz:
https://doaj.org/article/ddd7582963914757848181c6d8b5e60f
Autor:
Peter J. Cook, Rozario Thomas, Ram Kannan, Esther Sanchez de Leon, Alexander Drilon, Marc K. Rosenblum, Maurizio Scaltriti, Robert Benezra, Andrea Ventura
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-1 (2018)
Nature Communications 8: Article number: 15987 (2017); Published: 11 July 2017; Updated: 13 March 2018 In the original version of this Article, financial support was not fully acknowledged. The PDF and HTML versions of the Article have now been corre
Externí odkaz:
https://doaj.org/article/e3bc39779c1940f3b63041d39757508e
Autor:
Andrea Ventura, Rozario Thomas, Marc K. Rosenblum, Ram Kannan, Esther Sanchez de Leon, Robert Benezra, Peter J. Cook, Maurizio Scaltriti, Alexander Drilon
Publikováno v:
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-1 (2018)
Nature Communications, Vol 9, Iss 1, Pp 1-1 (2018)
The widespread application of high-throughput sequencing methods is resulting in the identification of a rapidly growing number of novel gene fusions caused by tumour-specific chromosomal rearrangements, whose oncogenic potential remains unknown. Her
Autor:
Maurizio Scaltriti, Rozario Thomas, Andrea Ventura, Marc K. Rosenblum, Ram Kannan, Peter J. Cook, Robert Benezra, Esther Sanchez de Leon, Alexander Drilon
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Nature Communications
Nature Communications
The widespread application of high-throughput sequencing methods is resulting in the identification of a rapidly growing number of novel gene fusions caused by tumour-specific chromosomal rearrangements, whose oncogenic potential remains unknown. Her
Autor:
Wei Wu, Ying Liu, Roshan Singh Thakur, Ian D. Hickson, Liqun Ren, Philipp H. Richter, Esther Sanchez De Leon, Özgün Özer, Fiorella Ghisays, Rahul Bhowmick, Ivan Vogel, John H.J. Petrini
Publikováno v:
Nature structural and molecular biology
Oncogene activation during tumorigenesis generates DNA replication stress, a known driver of genome rearrangements. In response to replication stress, certain loci, such as common fragile sites and telomeres, remain under-replicated during interphase