Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Esther Revai Lechtich"'
Autor:
Deepak Bhere, Nahid Arghiani, Esther Revai Lechtich, Yizheng Yao, Sarah Alsaab, Fengfeng Bei, Maryam M. Matin, Khalid Shah
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/3c3b499671664b92921c0532e4f22cfe
Autor:
Deepak Bhere, Sung Hugh Choi, Pim van de Donk, David Hope, Kiki Gortzak, Amina Kunnummal, Jasneet Khalsa, Esther Revai Lechtich, Clemens Reinshagen, Victoria Leon, Nabil Nissar, Wenya Linda Bi, Cheng Feng, Hongbin Li, Yu Shrike Zhang, Steven H. Liang, Neil Vasdev, Walid Ibn Essayed, Pablo Valdes Quevedo, Alexandra Golby, Naima Banouni, Anna Palagina, Reza Abdi, Brian Fury, Stelios Smirnakis, Alarice Lowe, Brock Reeve, Arthur Hiller, E. Antonio Chiocca, Glenn Prestwich, Hiroaki Wakimoto, Gerhard Bauer, Khalid Shah
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Abstract Cellular therapies offer a promising therapeutic strategy for the highly malignant brain tumor, glioblastoma (GBM). However, their clinical translation is limited by the lack of effective target identification and stringent testing in pre-cl
Externí odkaz:
https://doaj.org/article/c3728edd112e43e6baeb95ff129c6000
Autor:
Hannah J. Vaughan, Camila G. Zamboni, Nicholas P. Radant, Pranshu Bhardwaj, Esther Revai Lechtich, Laboni F. Hassan, Khalid Shah, Jordan J. Green
Publikováno v:
Molecular Therapy: Oncolytics, Vol 21, Iss , Pp 377-388 (2021)
Despite initial promise, tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-based approaches to cancer treatment have yet to yield a clinically approved therapy, due to delivery challenges, a lack of potency, and drug resistance. To addr
Externí odkaz:
https://doaj.org/article/a6c099a709f14d6e9ad64f6140f6855c
Autor:
Deepak Bhere, Nahid Arghiani, Esther Revai Lechtich, Yizheng Yao, Sarah Alsaab, Fengfeng Bei, Maryam M. Matin, Khalid Shah
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Abstract Dysregulation of miRNA expression has been implicated in cancer. Numerous strategies have been explored to modulate miR but sub-optimal delivery and inability to concurrently target multiple pathways involved in tumor progression have limite
Externí odkaz:
https://doaj.org/article/b320c564c7ac41faa451f7f557aa22c3
Autor:
Camila Gadens Zamboni, Laboni F. Hassan, Nicholas P. Radant, Pranshu Bhardwaj, Esther Revai Lechtich, Khalid Shah, Hannah J. Vaughan, Jordan J. Green
Publikováno v:
Molecular Therapy: Oncolytics, Vol 21, Iss, Pp 377-388 (2021)
Molecular Therapy Oncolytics
Molecular Therapy Oncolytics
Despite initial promise, tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-based approaches to cancer treatment have yet to yield a clinically approved therapy, due to delivery challenges, a lack of potency, and drug resistance. To addr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51ae52c2df5b1c4a7ebdba7297155638
https://doi.org/10.1016/j.omto.2021.04.004
https://doi.org/10.1016/j.omto.2021.04.004
Autor:
Yizheng Yao, Deepak Bhere, Khalid Shah, Esther Revai Lechtich, Fengfeng Bei, Maryam Moghaddam Matin, Nahid Arghiani, Sarah Alsaab
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports
Scientific Reports
Dysregulation of miRNA expression has been implicated in cancer. Numerous strategies have been explored to modulate miR but sub-optimal delivery and inability to concurrently target multiple pathways involved in tumor progression have limited their e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9da9a9359fc3872e589cd0a62a1b8458
https://doaj.org/article/b320c564c7ac41faa451f7f557aa22c3
https://doaj.org/article/b320c564c7ac41faa451f7f557aa22c3
Autor:
Joana L. Mora, Jefferey L. Falcone, Hikaru Sasaki, Wanlu Du, Clemens Reinshagen, Nobuhiko Kanaya, Nada Attia, Priscilla Kaliopi Brastianos, Susana Moleirinho, Aldebaran M. Hofer, Esther Revai Lechtich, Khalid Shah, Agnieszka Bronisz, Arnaldo Franco, Yohei Kitamura
Publikováno v:
Science Advances
This study presents a mechanism-based receptor-targeted cellular therapy approach to treat breast to brain metastasis.
Basal-like breast cancer (BLBC) shows brain metastatic (BM) capability and overexpresses EGFR and death-receptors 4/5 (DR4/5);
Basal-like breast cancer (BLBC) shows brain metastatic (BM) capability and overexpresses EGFR and death-receptors 4/5 (DR4/5);
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbb05a794a70dba20ac77cebc1fa3b24
https://pubmed.ncbi.nlm.nih.gov/33658202
https://pubmed.ncbi.nlm.nih.gov/33658202
Publikováno v:
International journal of molecular medicine. 48(1)
Glioblastomas (GBMs) are refractory to current treatments and novel therapeutic approaches need to be explored. Pro-apoptotic tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is tumor-specific and has been shown to induce apoptosis and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf17b45854bd9d5c78102ec8fee7d0ed
https://pubmed.ncbi.nlm.nih.gov/34080646
https://pubmed.ncbi.nlm.nih.gov/34080646
Autor:
Amina Kunnummal, Alarice C. Lowe, Alexandra J. Golby, Khalid Shah, David Hope, Esther Revai Lechtich, Neil Vasdev, Clemens Reinshagen, Deepak Bhere, Sung Hugh Choi, Kiki Gortzak, Hiroaki Wakimoto, Wenya Bi, Walid Ibn Essayed, Jasneet Kaur Khalsa, Huan Ling, Pim van de Donk
Publikováno v:
Neuro Oncol
Engineered stem cell therapeutics present a promising therapeutic strategy for glioblastoma (GBM). However, their clinical translation in GBM patients is limited due to lack of mouse models that mimic clinical GBM scenario, dearth of stratification t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95b0341772d92e1dd24b111ff7973401
https://europepmc.org/articles/PMC6846239/
https://europepmc.org/articles/PMC6846239/
Autor:
Yong Hoi Lee, Suriyan Ponnusamy, Kuan Onn Tan, Ramesh Narayanan, Siew Wai Pang, Khalid Shah, Samson Eugin Simon, Esther Revai Lechtich, Chit Laa Poh
Publikováno v:
Journal of cancer research and clinical oncology. 146(7)
Although important for apoptosis, the signaling pathway involving MOAP-1(Modulator of Apoptosis 1), RASSF1A (RAS association domain family 1A), and Bax (Bcl-2 associated X protein) is likely to be dysfunctional in many types of human cancers due to m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b273986a51afb43f2f87236bbb906f4d
https://pubmed.ncbi.nlm.nih.gov/32377840
https://pubmed.ncbi.nlm.nih.gov/32377840