Výsledky vyhledávání - "Esther Pirak"

Targeting multidrug resistant tumor cells with a recombinant single-chain FV fragment directed to P-glycoprotein

Autor: Esther Pirak, Yoram Reiter, Yehuda G. Assaraf, Revital Niv, Dina Segal

Publikováno v: International Journal of Cancer. 94:864-872

The MDR1 gene product P-glycoprotein (Pgp) plays a key role in multidrug resistance of cancer cells. Pgp is an ATP-driven efflux pump that extrudes a variety of dissimilar hydrophobic cytotoxic compounds. P-glycoprotein overexpression results in mult

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::666cc22176bd292c703efdd7264f57ac
https://doi.org/10.1002/ijc.1552

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